pharm 1

Question 1

Specialized area of contact between the neurons where the transmission of information takes place

Answer 1

synapse

Question 2

types of synapse signaling

Answer 2

electrical: rare in mammals
Chemical: vast majority

Question 3

passage of an electrical impulse along an axon

Answer 3

conduction

Question 4

passage of an impulse across a synaptic or neuroeffector junction

Answer 4

transmission

Question 5

action potential reaches presynaptic termination. activation of voltage dependent _____

Answer 5

Ca+2 channels

Question 6

two types of neurotransmitter receptors

Answer 6

ionic channels operated by ligand: ionotropic receptors

receptors coupled to G proteins: metabotropic receptors

Question 7

two types of postsynaptic potentials

Answer 7

excitatory postsynaptic potential

inhibitory postsynaptic potential

Question 8

a single excitatory postsynaptic potential will_________

Answer 8

not produce depolarization

Question 9

biomolecule that is poured from existing vesicles in the presynaptic neuron into the synaptic space and produces a change in the membrane potential of the postsynaptic neuron

Answer 9

neurotransmitter

Question 10

where are neurotransmitters synthesized and stored?

Answer 10

synthesized in the region of the axonal terminals and stored in the synaptic vesicles

Question 11

how are neurotransmitters stored?

Answer 11

by an electrochemical gradient generated by the vesicular proton pump (vesicular ATPase)

Question 12

neuropeptides (proteins), act at lower concentrations, receptors in post or presynaptic membranes, do not produce EPSP/ IPSP, slower and longer lasting effects

Answer 12

neuromodulators such as CCK (satiety/ no pain), caffeine