Pharm Flashcards

1
Q

symptoms of aspirin overdose

A
  • sweating (aspirate)
  • tachypnoea (respirate)
  • tinnitus (aspiringing)
  • vomiting
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2
Q

aspirin overdose treatment

A
  • supportive
  • charcoal within 1 hour
  • haemodialysis in severe overdose
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3
Q

signs of severe aspirin overdose

A
  • pulmonary oedema
  • seizures
  • persistent acidosis
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4
Q

what enzyme metabolises paracetamol

A

CYP450

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5
Q

symptoms of paracetamol overdose

A
  • asymptomatic for the first 24 hrs
  • RUQ pain and vomiting in the next 2 days
  • liver failure eventually
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6
Q

treatment for paracetamol overdose

A

IV acetyl cysteine

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7
Q

triad of opiate overdose

A
  • respiratory depression
  • reduced consciousness
  • constricted pupils
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8
Q

treatment for opiate overdose

A

naloxone

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9
Q

symptoms of cocaine overdose

A
  • dilated pupils
  • sweating
  • tachycardia
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10
Q

symptoms of tricyclic overdose

A
  • dry mouth
  • dilated pupils
  • tachycardia
  • arrhythmias
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11
Q

2 ECG changes in tricyclic overdose

A
  • sinus tachycardia
  • wide QRS
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12
Q

treatment for tricyclic overdose

A

IV bicarbonate

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