Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

ALS > pharm > Flashcards

pharm Flashcards

(69 cards)

Start Studying
1
Q

What is the classification of Acetaminiphen?

A

Analgesic
Antipyretic (ALS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Contraindication for acetaminophen? (4)

A

-hypersensitivity
-alcoholic hepatitis or liver dysfunction
-acute liver injury
-acetaminophen induced liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Adult dose acetaminophen

A

500- 1 g
repeat after 4 hours to a
max dose of 3g in 24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Acetaminophen Pediatric dose for under 30 kg

A

15mg/kg PO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Acetaminophen Pediatric dose for 30-50 kg:

A

500 mg PO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Acetaminophen Pediatric dose for over 50 kg

A

500-1g, to make 24 hour dose of 75 mg/kg (do not exceed 5 doses in 24 hrs in ped under 12 years)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Acetaminophen liquid formula?

A

80mg/ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mechanism of action of acetaminophen?

A

inhibits prostaglanding synthetase in the CNS reducing pain and pyrexia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pharmocokinetics of Acetaminophen PO?
Onset:
Peak:
Duration:

A

onset: 30 min
Peak: 1-3 hours
duration: 4 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pharmocokinetics of Acetaminophen IV?
Onset:
Peak:
Duration:

A

Onset: 15 minutes
peak: 1 hour
duration: 4-6 hours (analgesia) and over 6 hours of antipyresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is a toxic dose of acetaminophen

A

after a single dose of more than 7.5 g in adults of 150mg/kg pediatrics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Classification of ASA

A

Antiplatelet and antithrombotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

mechanism of action for ASA

A

it inhibits the formation of thromboxane A2, which is a potent platelet aggregator and vasoconstrictor. The platelet effects are irreversible and last for the life of the platelet (7-10 days)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Adenosine classification

A

antiarrhythmic and endogenous nucleoside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Indications for Adenosine

A

Conversion of SVT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Contraindicated (3 things)

A

1-Hypersensitivity
2- second/third degree heart block
3- sick sinus syndrome (print rhythm) in patients without artificial pacemaker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Adenosine dosage:

A

inital dose of 6 mg, followed by 12 mg rapid IV push

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Mechanism of action for adenosine

A

slows the conduction of the electrical impulses through the AV node

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Pharmocokinetics of adenosine

A

onset: rapid
peak: rapid
duration: 10 seconds or less

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

adverse effects of Adenosine

A

lightheadedness, flushing, SOB, chest pressure and nausea- usually self limiting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Warnings/precautions for Adenosine (2 things)

A
  • rare cases of VF associated with adenosine in patients taking digoxin, or digoxin and verapamil- consider clinicall to discuss
    -may worsem bronchoconstriction in pts with COPD/Asthma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Amiodarone classification

A

anti-arrhythmic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Amiodarone indications

A

1- VFIB
2- pulseless vtac
3- unstable vtac
4- recurrent VTAC following cardioversion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Amiodarone dosages for VFIB/VTAC
300 mg IV push, followed by 150 mg IV after 10 minutes if VF/pVT persists
26
Amiodarone dosage for unstable vtac and recurrant vtac following cardioversion?
150mg IV over 10 minutes
27
Amiodarone used in stable monomorphic WCT or symptomatic runs of WCT?
Yes, 150 mg over 10 minutes- BUT YOU MUST CALL CLINICALL
28
Amiodarone for pediatrics?
not established- call clinicall for tx plan
29
Describe the mechanism of action for Amiodarone in regards to its characteristics of all 4 Vaughn-Williams classes of anti-arrhythmics
1) Blocks NA channels in heart, 2)antagonizes beta adrenoreceptors to inhibit sympathetic activity, 3) produces negative chronotropic effects in nodal tissues 4) lengthens cardiac action potential, 5) also slows conduction and prolongs refractoriness by blocking potassium channels.
30
pharmacokinetics of amiodarone?
Onset: 2 minutes Peak: 20 minutes duration: 2 hours
31
Adverse Effects:
- hypotension (if this happens during an infusion, just slow the rate) -nausea and bradycardia -QT prolongation
32
Drug interactions with Amiodarone?
be careful as they may potentiate the effects of beta blockers, calcium channel blockers or digoxin and should be used with caution
33
Atropine classification
anticholinergic antimuscarinic
34
Atropine indications (5)
1- restoration of bradydysrhythmias 2-Sinus brady less than 50 with hemodynamic compromise 3- bradycardia secondary to AV node blocks 4- treatment for ogranophosphate poisoning 5- Control of secretions in palliative care
35
Contraindications to Atropine (6 things)
1- hypersensitivity 2-tachycardia 3-narrow-angle glaucoma 4- thyrotoxicosis 5- prostate hypertrophy 6- myasthenia gravis
36
Atropine dosage for bradycardia?
.6mg IV push to max dose of .04mg/kg or 3 mg in most patients
37
Atropine dosage for organophosphate toxicity
1-2 mg Im/IV repeat 5-60 minutes until symptoms resolve
38
Atropine dosage for secretions in palliative care
.6mg IM
39
If atropine is given too slow, or underdosed, what are the potential outcomes?
Paradoxical slowing of HR
40
Can pediatrics have atropine?
yes- follow weight based tx- .02mg/kg
41
Indications for calcium chloride (3)
1- Cardiac arrest due to suspected hyperkalemia (renal failure, DKA) 2- suspected hyperkalemia with cardiovascular toxicity (wide QRS, peaked T, hemodynamic instability) 3- Calcium channel blocker OD with sympathetic bradycarida or hemodynamic instability
42
Contraindication for Calcium Chloride
hypersensitivity primary or secondary hypercalcemia
43
Calcium chloride adult dosages
1-2g IV over 10 minutes can repeat once in 10 minutes if indications are still present
44
Calcium chloride for pediatric dosing
20mg/kg over 3 minutes, max single dose of 1 g -can repeat once in 10 minutes if indications are still present
45
What is the mechanism of action for Calcium Chloride?
nerve conduction, muscle contraction, renal function and coagulation- administration of calcium in prehospital is intended to improve mycardial contractility and ventricular automaticity
46
Pharmocokinetics of clacium chloride
IV- 5-15 minutes duration- dose dependent (can be up to 4 hours)
47
Adverse effects of calcium chloride
-tissue irritation (most common side of effect of calcium administration) -hypotension- cardiac arrhythmias, and cardiac arrest may occur if calcium is given too quickly -calcium chloride may precipitate or worsen acidosis, cor pulmonale, or renal and respiratory disease
48
Dexamethasone classifications
anti-inflammatory agen, systemic corticosteroid
49
Dexamethasone contraindications
- systemic fungal infections -hypersensitivity to dexamethasone or other cortiscosteroids
50
Dose for Dexamethasone
8mg Iv/IO/IM/PO (PO preferred)
51
Pediatric dose for dexamethasone
.6mg/kg to max of 16 mg
52
mechanism of action for dexamthasone
suppresses neurtrophil migration, decreasing production of inflammatory mediators and reversng capillary permeability
53
Dopamine classification and indications
sympathomimetic alpha and beta agonist dopaminergic agonist indicated for CCP for symptomatic hypotension in the absense of hypovolemia
54
Dopamine dosages (based on dopaminergic, beta and alpha effects)
2 mcg/kg/min for dopaminergic effects 5-10 mcg/kg/min IV beta effects 10-20 mcg/kg alpha effects -for hemodynamic unstable patients dose range is 5-20 mcg/kg/min
55
EPI dose for anaphylaxis
.5mg IM
56
EPI dose for anaphylaxis
50-100mcg IV
57
Cardiac Arrest Epi dose
1 mg q 2-4 minutes
58
peri-arrest hypotension epi dose
10mcg/ IV q 2-3 minutes
59
Brady cardia Epi dose?
2-10mcg/minute Iv/Io infusion
60
Pediatric Epi dose anaphylaxis
.01 mg/kg
61
Pediatric bronchospasm with impending arrest Epi dose
.01 mg/kg up to max .5mg
62
Pediatric croup Epi dose over 1 year
5mg nebulizer
63
under 1 year epi dose nebulized for croupe dosage?
.5mg/kg to max of 5mg
64
Pediatric Cardiac arrest Epi dosage
.01mg/kg IV
65
Pediatric pre-arrrest anaphylaxis Epi dosage
5mcg/kg/IV
66
Pediatric peri-intubation resusitation dose for Epi
1 mcg/kg
67
Pharmocokinetics of EPI
onset: 30-90 second IM, 30 secs IV peak: 4-10 min IM, 3-5 min IV Duration: 5-10 min (IM/IV)
68
Diphenhydramine contraindications?
-allergy to -neonates -premature infants
69

ALS (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions