pharm Flashcards
(25 cards)
Clonidine MOA
alpha 2 agonist, acts centrally on GCPR –> Gi
clonidine indication
rebound HTN, last resort drug
clonidine application
transdermal
clonidine ADE
rebound HTN (must taper pt off), dry mouth, sedation (central acting)
Ritonavir, bocepravir, telapravir MOA
protease inhibitor
ritonavir indication
HIV
telapravir indication
Hepatitis C
protease inhibitor ADE
lipodystrophy, hyperglycemia, hyperlipidemia, hyperinsulinemia, GI intolerance
Mainstay of treatment for COPD
bronchodilators
albuterol MOA
short acting beta2 agonist
albuterol ADE
tremors, tachycardia, hypokalemia (increased Na/K ATPase activity)
1st line treatment of trichomoniasis
metornidazole
1st line treatment of bacterial vaginosis
metronidazole
loop diurectics MOA
inhibit the Na/K/Cl channel in the thick ascending limb of the loop of henle
loop diuretics
furosemide, Torasemide, Bumetanide
griseofulvin indication
taken orally for superficial fungal infections: used for tinea and ringworm
griseofulvin ADEs
CYP P450 induction, espcially with warfarin –> decreases the efficacy and half life of other drugs
teratogenic, carcinogenic
griseofulvin MOA
interferes with microtubules and disrupts mitosis
main ADE of steroid therapy
cushinoid syndrome: buffalo hump and moon facies, insulin resistance, red face, abdominal striae, osteoporosis (hip fractures)
Special incidences where you would use a Cox-2 specific inhibitor
to control inflammation in patients with high GI risk but low risk of CV incident
Amiodarone MOA
blocks K channels, prolonging depolarization
amiodarone important ADE
pulmonary fibrosis
what class of antiarrhythmic is amiodarone
class III
albenzadol indication
parasitic worm infections such as pinworms and hook worms
