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pharm Flashcards

(52 cards)

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1
Q

Bethanechol

A

Cholimimetic -> Bethany call me if you want to activate your bowel and bladder

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2
Q

Carbachol

A

ACh like, vs glaucoma

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3
Q

Pilocarpine

A

Cholinomimetic, stimulates sweat/tears/saliva, vs glaucoma

Cry drool and sweat on your PILOw

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4
Q

Methacholine

A

Cholinomimetic, used to test vs asthma, stimulates muscarinic receptors in airway

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5
Q

Neostigmine

A

ACh esterase inhibitor -> vs myasthenia gravis

Does NOT enter CNS

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6
Q

Pyridostigmine

A

ACh esterase inhibitor, does not penetrate CNS, long acting vs Myasthenia Gravis

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7
Q

Edrophonium

A

Short acting ACh esterase inhibitor to test for Myasthenia Gravis

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8
Q

Physostigmine

A

ACh esterase inhibitor that CROSSES the blood brain barrier

vs atropine overdose

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9
Q

Donezepil

A

ACh esterase inhibitor vs Alzheimer’s disease

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10
Q

What is the therapy vs Cholinesterase inhibitor poisoning?

A

Atropine + pralidoxime

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11
Q

Atropine, Tropicamide

A

Muscarinic antagonist, produces mydriasis

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12
Q

Benztropine

A

Muscarinic antagonist vs Parkinsons

PARK your mercedes BENZ

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13
Q

Scopolamine

A

Muscarinic antagonist vs Motion sickness

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14
Q

Ipratropium

A

Muscarinic antagonist vs COPD/asthma -> I PRAy I can breathe again

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15
Q

Oxybutynin

A

Muscarinic antagonist, vs Bladder spasm, reduces urgency

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16
Q

Glycopyrrolate

A

Muscarinic antagonist, decreases airway secretion

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17
Q

Atropine toxicity

A

Inc. Body temp
Dry and flushed skin
Disorientation
Cycloplegia

similar symptoms found in JIMSON WEED

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18
Q

Epinephrine

A

Agonist of Alpha and Beta receptors

Used vs anaphylaxis, glaucoma, asthma, hypotension

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19
Q

Norepinephrine

A

Alpha agonist

B1 agonist!!! not b2!!!!

Used vs hypotension

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20
Q

Isoproterenol

A

B agonist only!!

Vs torsades de pointes

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21
Q

Dopamine

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A

High dose - alpha agonist
Medium dose - beta agonist
Low dose - D1 agonist

Use: Vs shock and heart failure

22
Q

Dobutamine

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A

B1 agonist primarily

Vs heart failure or used in cardiac stress testing

23
Q

Phenylephrine

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A

Alpha agonist only

Vs hypotension, ocular procedures

24
Q

Albuterol/salmeterol/terbutaline

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A

B2&raquo_space;> B1 agonist

Bronchodilation in ashtma

25
Ritodrine
B2 agonist vs premature uterine contractions
26
Amphetamine
Increases release of NE, decreases reuptake Used vs narcolepsy
27
Ephedrine
Sympathomimetic, vs nasal congestion
28
Cocaine
Decreased reuptake of NE Causes vasoconstriction and anesthesia DO NOT MIX WITH B BLOCKER -> causes extreme alpha agonist activity and hypertension
29
What is the effect on heart rate of Norepinephrine?
Decreased heart rate as MAP increases
30
Clonidine/Methyldopa
Sympathoplegic -> Alpha 2 agonist -> decreases sympathetic outflow Used in hypertension
31
Phenoxybenzamine
Alpha blocker -> irreversible Used vs pheochromocytoma Leads to orthostatic hypotension and reflex tachycardia
32
Phentolamine
Reversible alpha blocker Give to patients on MAO inhibitor who eat foods with tyramine
33
Prazosin/terazosin
-osin ending -> alpha 1 blocker!! Vs Hypertension or urinary retention 1st dose: gives orthostatic hypotension!!
34
Mirtazipine
Alpha 2 blocker Vs depression -> leads to sedation and increased appetite
35
What are contraindications to Beta blockers?
Asthma Diabetes
36
What B blockers are B1 selective? Which are B1 and B2 (generalized)?
B1 selective -> A-M (Metoprolol) B1/B2 nonselective -> N-Z
37
What B blockers are Alpha and Beta blockers?
Carvedilol, Labetalol
38
What B blockers are partial B agonist?
Pindolol, Acebutalol
39
Acetaminophen toxicity antidote
N acetylcysteine (inc. glutathione)
40
Salicylates toxicity antitodte
NaHCO3
41
Amphetamines tox antidote
NH4Cl
42
B blocker antidote
Glucagon
43
Digitalis toxicity antidote
K+, Mg2+
44
Lead toxicity antidote
Penicillamine, Dimercaprol
45
Cyanide toxicity antidote
Nitrite + thiosulfate
46
Ethylene glycol toxicity antidote
Fomepizole
47
Opioid toxicity antidote
Naloxone
48
Benzodiazepine toxicity antidote
Flumazenil
49
TCA toxicity antidote
NaHCO3
50
Heparin toxicity antidote
Protamiine
51
Warfarin toxicity antidote
Vitamin K
52
Theophylline toxicity antidote
B blocker

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