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NMSP Exam 1 > [PHARM] CNS Stimulants [Iszard] > Flashcards

[PHARM] CNS Stimulants [Iszard] Flashcards

1
Q

What are the two major categories of ADHD medications?

A

Stimulants

Non-Stimulants

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2
Q

What is the MOA of stimulants used for ADHD?

A

Stimulants enhance neurotransmitter transmission by serving as direct and indirect non-catecholamine sympathomimetics

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3
Q

What are some of the major side effects of stimulants?

A

Dyspepsia/GI distress

Headache

Decreased appetite

Insomnia

Irritability

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4
Q

What are some of the RARE side effects of stimulants?

A

Priapism

Seizures

Sudden cardiac death

Stroke & MI

Chemical leukoderma

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5
Q

Formulation abbreviations

What do the following mean?

IR

ER/XR

LA

CD

ODT

A

IR = Immediate release

ER/XR = extended release

LA = long acting

CD = controlled delivery

ODT = oral disintegrating tablet

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6
Q

What are some considerations you should have with stimulants?

A

Can induce anxiety and agitation

Can cause symptomatic CV disease

Moderate to severe HTN

Glaucoma

Tic formation

Seizures

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7
Q

What are the prescribing restrictions for stimulants?

A

Stimulants are controlled substances

(1 month supply only, no refills, no samples)

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8
Q

Which of the following amphetamine based stimulants are produced in the LIQUID form?

  • Dextroamphetamine/AMP/Adderall
  • Dextroamphetamine sulfate/ProCentral
  • Amphetamine sulfate/Eveko
  • Dextroamphetamine/Zendidi
A

-Dextroamphetamine/AMP/Adderall

-Dextroamphetamine sulfate/ProCentral

  • Amphetamine sulfate/Eveko
  • Dextroamphetamine/Zendidi
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9
Q

Which of the following amphetamine-based stimulants is produced in the CAPsule form?

  • Dextroamphetamine/AMP/Adderall
  • Dextroamphetamine sulfate/ProCentral
  • Amphetamine sulfate/Eveko
  • Dextroamphetamine/Zendidi
A
  • Dextroamphetamine/AMP/Adderall
  • Dextroamphetamine sulfate/ProCentral

-Amphetamine sulfate/Eveko

-Dextroamphetamine/Zendidi

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10
Q

Which of the following amphetamine-based stimulants is produced in the TABlet form?

  • Dextroamphetamine/AMP/Adderall
  • Dextroamphetamine sulfate/ProCentral
  • Amphetamine sulfate/Eveko
  • Dextroamphetamine/Zendidi
A

-Dextroamphetamine/AMP/Adderall

  • Dextroamphetamine sulfate/ProCentral
  • Amphetamine sulfate/Eveko

-Dextroamphetamine/Zendidi

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11
Q

What is the ONLY amphetamine based stimulant with EXTENDED RELEASE that is in the liquid form?

A

Amphentamine/ DyanavelXR

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12
Q

What are the (3) methylphenidate based stimulants with immediate release?

A

Dexmethylphenidate/Focalin

Methylphenidate/Methylin

Methylphenidate/Ritalin

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13
Q

Which of the following is in the TAB form vs LIQUID form?

Dexmethylphenidate/Focalin

Methylphenidate/Methylin

Methylphenidate/Ritalin

A

Dexmethylphenidate/Focalin (TAB)

Methylphenidate/Methylin (LIQ)

Methylphenidate/Ritalin (TAB)

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14
Q

What are the (2) methylphenidate-based stimulants with SUSTAINED release?

A

Methylphenidate/ritalin

Methamphetamine/desoxyn

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15
Q

What is the one methylphenidate-based stimulant with EXTENDED release that if formulated as a transdermal patch?

A

Methylphenidate Transdermal/ Daytrans

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16
Q

What is the one methylphenidate-based stimulant with EXTENDED release that if formulated as a chewable tablet?

A

Methylphenidate HCL/ QuilitChew

17
Q

What is the one methylphenidate-based stimulant with EXTENDED release that if formulated as a liquid?

A

Methylphenidate/Quillivant XR

18
Q

What are the general MOA of non-stimulants for ADHD?

A

Enhance neurotransmitter transmission

(Inhibition of NE pre-synaptic reuptake)

(Agonists of CNS alpha-2A adrenergic receptors)

19
Q

What type of patient with ADHD is a good candidate for non-stimulants?

A

Useful for patients intolerant of stimulant effects of stimulant class

20
Q

What is the scheduling class of non-stimulants?

A

Non-scheduled

Refills and samples are permitted up to 1 year time frame

21
Q

What is a drug class (used as non-stimulant for ADHD) that is classified for it’s primary use in a condition other than treatment of ADHD?

A

Antihypertensives

Clonidine

Guanfacine

22
Q

What is a ingestion consideration to make with the non-stimulatns (alpha2 agonists)?

A

DO NOT crush/chew or break tablets

(Guanfacine, Clonidine)

23
Q

*Remember to focus on the FORMULATION of the drugs

There will be several questions regarding formulation

*Remember that ONLY for this lecture, you should know the generic names of the CNS stimulant drugs

A

NMSP Exam 1 (22 decks)

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