Pharm: Hem/Onc II

Question 1

What is FFP made of?

Answer 1

complex mix of H2O, PROs, CHOs, Fats, & vitamins

Question 2

Which blood component is bascially not found in FFP?

Answer 2

platelets

Question 3

FFP and Pregnancy

Answer 3

not clear if safe

Question 4

Can FFP be used to reverse Warfarin?

Answer 4

Yes

Question 5

Fresh Frozen Plasma: Uses

Answer 5

• Pts w/ acquired deficiencies
  due to liver disease, undergoing cardiac surgery, liver transplant
  or on anticoags
• Plasma exchange in pts w/ TTP

Question 6

Fresh Frozen Plasma: MOA

Answer 6

Octaplas replaces human plasma proteins

Question 7

Fresh Frozen Plasma: Serious Rxns

Answer 7

anaphylactic shock
severe hypotension

Question 10

Platelets: Uses

Answer 10

• Depends on platelet count

In Adults (e.g.):
Leukemia
Aplastic anemia
Platelet dysfunction
Major surgery
Ocular surgery
Neurosurgery

Question 11

Platelets: MOA

Answer 11

Platelets contribute their hemostatic capacity via adhesion, activation and aggregation

Question 12

Platelets: Contraindications

Answer 12

• Thrombotic thrombocytopenic purpura (TTP)
• Hemolytic uremic syndrome (HUS)
• Heparin induced thrombocytopenia (HIT)

Question 13

Packed Red Blood Cells: Uses

Answer 13

• Insufficient Tissue Oxygen Delivery Due to Active Bleeding
• Symptomatic Anemia

Question 14

Packed Red Blood Cells: MOA

Answer 14

• Incr blood oxygen carrying capacity.
• Restores intravascular volume in acute active bleeding
• Improves platelet function in pts w/ uremic bleeding.

Question 15

Packed Red Blood Cells: Adverse Rxns

Answer 15

Hemolytic Transfusion Rxns
Septic Rxns
Transfusion Related Acute Lung Injury (TRALI)

Question 16

Packed Red Blood Cells: Safety Facts

Answer 16

• don’t use to tx anemia that can be corrected otherwise
• solely for providing blood volume, feeling unwell, or improving wound healing

Question 17

What should be done if there is a transfusion rxns?

Answer 17

stop transfusion, stabilize pt. notify blood bank

Question 18

: Uses

Question 19

: MOA

Question 20

: Serious Rxns

Question 21

: Safety

Question 22

: Uses

Question 23

: Serious Rxns

Question 24

: MOA

Question 25

: Common Rxns

Question 26

: Uses

Question 27

: Safety

Question 28

: MOA

Question 29

: Serious Rxns

Question 30

: Common Rxns

Question 31

: Serious Rxns

Question 32

: Safety

Question 33

: Uses

Question 34

: Saftey

Question 35

: Common Rxns

Question 36

: MOA

Question 37

: Uses

Question 38

: Safety

Question 39

: Safety

Question 40

: MOA

Question 41

: Common Rxns

Question 42

: Uses

Question 43

: MOA

Question 44

: Serious Rxns

Question 45

: Common Rxns

Question 46

: MOA

Question 47

: Common Rxns

Question 48

: Serious Rxns

Question 49

: Safety

Question 50

: Serious Rxns

Question 51

: Uses

Question 52

: Serious Rxns

Question 53

: Uses

Question 54

: Common Rxns

Question 55

: MOA

Question 56

: Safety