PHARM list Final Drugs Flashcards by Connor Hancock

(Adenosine) Class:
Dynamics:

Administering notes:

= Nucleoside, Misc/ Antiarrhythmic
= binds to adenosine A1 receptors thus efflux of K & inhibits Ca influx (in AR cells), thus hyperpolarization/slows AV of ARcells (SA/AV node)
= rapid IVP followed by rapid flush(20ml) & can be accomplished best w/ utilizing 3-way stopcock

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(Adenosine) Indications:

Contra:

Side Effects:
1st dose:
2nd dose:
Dosage note:

= 1st line med w/ stable narrow complex SVT, Regular & monomorphic wide-complex tachycardia thought from reentry SVT (SVT w/ BBB)
= A-fib/ A-flutter, Torsades de pointes, Poison/drug-induced T-cardia, 2/3rd AVB, WPW, DOESNT CONVERT A-FIB/FLUTTER
= small period asystole & ventricular ectopy are common after admin
= 6mg rapid IV/O push followed w/ rapid flush of fluid
= 12mg rapid IV/O push followed w/ rapid flush of fluid
= half 1st dose in PTs receiving dipyridamole or carbamazepine, heart transplant, Or if by central access

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(Albuterol) Class:
Dynamics:
Indi:
Contra:

= B/Adrenergic agonist
= B agonist w/ preference for B2 receptors
= Bronchospasm, Allergies/anaphylaxis, Hyperkalemia
= hypersensitivity

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(Albuterol) Effects:
Adult Dose:
Pedi Dose:

= Palpitations, Anxiety, Jitters, H/A, Dizziness, Tachycardia
= 2.5mg/3ml SVN: Every 15-20 Mins as needed
= 1.25-2.5mg/1.5-3mL SVN: Every 15-20 Mins as needed

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(Amiodarone) Class:
Dynamics:
Indi:

B/c its toxicity indi:
W/ expert consultation may be used for:
Terminal elimination:

= Class III antiarrhythmic
= Slows K+ efflux delaying repolarization
= VF/Pulseless VT-no/response to shock CPR & Epi, Recurrent hemodynamically unstable VT w/ pulse
= PT w/ life-threatening arrhythmias w/ monitoring
= some atrial & ventricular rhythms w/ life-threatening hypoBP
= Extremely long (half-life lasts max 40 days)

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(Amiodarone) Contra:
Effects:
Caution b/c:

= Allergic, Bradycardias w/ AV blocks, Breastfeeding mothers
= Severe hypotension, Bradycardia, Prolong QT which can lead to TdP
= Toxicity, Causes severe BP drop, Prolong QT which can lead to TdP

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(Amiodarone) Max total dose per day:
Slow Infusion dose:
Maintenance Infusion dose:
VF/Pulseless & VT Cardiac Arrest Unresponsive 1st Dosage:
VF/Pulseless & VT Cardiac Arrest Unresponsive 2nd Dosage:
Life-Threatening Arrhythmia 1st Dosage:
Life-Threatening Arrhythmia 2nd Dosage:

= 2.2 grams
= 360 mg IV 6Hrs (1mg/min)
= 540 mg IV 18Hrs (0.5 mg/min)
= 1st Dose: 300 mg IV/O push
= 2nd Dose: 150 mg IV/O push if needed
= 1st Dose: Rapid Infusion 150 mg/10 mins (15 mg/min)
= 2nd Dose: 150mg/10 mins (15 mg/min) if needed

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(Atropine) Class:
Dynamics:

= Parasympatholytic
= Selectively blocks M-receptors inhibiting PSNS thus SNS takes over

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(Atropine) Ind:

Contra:

Caution w/ b/c med:

= 1st line med for sinus Bcardia, Maybe beneficial w/ AV nodal block, Organophosphate poisoning
=Allergic, caution w/ H. ischemia, hypothermBcardia (<84) <0.5mg dose make Parasympathomimetic effects
= Myocardial ischemia & hypoxia b/c med +myocardial O2 demands

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(Atropine) Effects:
Max dose:
Bradycardia (w/ or w/o ACS) dose:
Severe clinical conditions dose:
Organophosphate Poisoning Dose:

= Blurred vision, Dry mouth, Mydriasis, Confusion
= 0.04 mg/kg or 3 mg
= 1 mg IVP 3-5 mins as needed w/ max dose 3mg or 0.04 mg/kg
= 1 mg IVP every 3 mins w/ max dose 3mg or 0.04 mg/kg
= 2-4 mg (or higher) IVP

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(Ipratropium/Atrovent) Class:
Dynamics:
Indi:
Contra:

= Selective-Parasympatholytic
= Anticholinergic Selectively block M-receptors: Synergism w/ Albuterol
= Bronchospasm w/ obstructive lung-disease (asthma,COPD)
= hypersensitivity, No/Lil effect given by itself

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(Ipratropium/Atrovent) Effects:
Adult Dose:
Pedi Dose:

= Blurry-vision, Dry mouth, Dilated pupils, Dry Cough, Confusion
= 500 mcg/2.5 mL via neb
= 250-500 mcg/1.25-2.5 mL via neb

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(Dextrose) Class:
Dynamics:
Indi:
Contra:
Effects:

= Carbohydrate
= Water-soluble monosaccharide
= Correction of hypoglycemia
= Known hyperglycemia
= Tissue necrosis w/ extravasation, May worsen hyperglycemia

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(Dextrose) Adult Dose:
Pedi Dose:

= 25G IV/IO or D10 in 50 mL(5G) IV/IO boluses (max 250 mL)
= 5-10 mL’s/kg of D10

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(Diltiazem) Class:
Dynamics:
Indi:

Contra:

= Class IV Antiarrhythmic (Ca Channel Blocker)
= Slows AP of autorhythmic cells by blocking Ca-channels
= 1st line med for A-Fib/Flutter with RVR (>150BPM), 2nd line med for SVT after adenosine admin/
= SBP<90, CHF/Cardio Shock, Wide-Complex T/cardia, WPW, Hypersensitivity

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(Diltiazem) Effects:
1st dose:
2nd dose:

= HypoBP, Severe CHF used w/ Beta-Blockers, N/V/D, Dizziness, H/A
= 0.25 mg/kg (max dose 20 mg)
= 0.35 mg/kg (max dose 25 mg)

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(Dopamine) class:
Action:

= Sympathetic agonist
= A/B-adrenergic agonist, Rate dependent, vasopressor. +/otropics

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(Dopamine) Indi:
Contra:
DONT:

= CHF, HypoBP/shock signs, 2nd-line Bcardia (after Atropine w/Adult)
= hypovolemic PTs til Vol replacement, Pheochromocytoma his
= MIX W/ Sodium-Bicarb!!! & open WIDE OPEN!

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(Dopamine) Effects:

Dosing:
Adult & Pedi Cardiac dose:
Adult & Pedi Vasopressor dose:

= Hypertension, Palpitations, H/A, Dizziness, Can worsen cardiac ischemia, Tissue necrosis W/ Extravasation
= 2–20 mcg/kg/min Titrate to patients response
= 5-10mcg/kg/min
= 10-20 mcg/kg/min

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(Epi 1:10,) Class:
Dynamics:
Indications:
Contraindications:

= Sympathomimetic
= Powerful Alpha & Beta agonist
= Cardiac arrest, Bcardia, Normovolemic hypoBP, Anaphylaxis, Asthma
= rewards over risks so really none

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(Epi 1:10,) Effects:

Admin via:
(Adult) Cardiac Arrest dose:
(Adult) Bradycardia dose:
(PEDI) Bradycardia/Cardiac Arrest dose:
(PEDI) Hypoperfusion & Severe anaphylaxis dose:

= Palpitations, Anxiety, Jitters, H/A, Dizziness, HyperBP, Tcardia, Can worsen cardiac ischemia
= IV infusion drip
= 1mg IVP/IOP every 3-5 mins
= 2-10 mcg/min IV/IO infusion
= 0.01 mg/kg or 0.1 mL/kg
= 0.1-1 mcg/kg/min infusion by Mixing 1mg of Epi 1:10 into 1L IV bag

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(Epi 1:1,) Class:
Dynamics:
Indi:
Contra:

= Sympathomimetic, SNS
= Potent A/B-agonist
= Severe bronchospasm, Allergies/anaphylaxis
= Few in emergent setting, Benefits>Risks, NEVER WITH-HOLD

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(Epi 1:1,) Effects:
Admin/ via:
Adult Dose:
Pedi Dose:

Study These Flashcards

= Can worsen H-ischemia, Palp/s, Anxiety, Jitters, H/A, Dizzy, Tcardia
= IM
= 0.3 mg(Asthma/COPD) & Up to 0.5 mg for anaphylaxis
= 0.01 mg/kg IM w/ max dose of 0.3 mg

(Glucagon) Class:
Action:

Study These Flashcards

= Hormone
= +BGL w/ lysis of glycogen to glucose (IM route) Binds to Glucagon receptors & stim/s adenyl cyclase raising cAMP (IV route). Increase cAMP makes up-regulation of Ca-channels in SA & AV nodal cells

(Glucagon) Indi: Contra: Effects:

= Hypoglycemia w/ IV/IO not obtainable, Bradycardia suspected from Beta-Blocker or Ca-Channel Blocker OD = Hypersensitivity & Bradycardia from other etiology = Anxiety, Palp/s, H/A, N/V, Increased BGL(can led to hyperglycemia)

(Glucagon) Hypoglycemia Adult Dose: Hypoglycemia Pedi Doses:

= 1 mg IM/IN = <20Kg 0.5 mg IM/IN & >20Kg 1mg IM/IN

(Lidocaine) Class: Dynamics:

= Class Ib Antiarrhythmic = Blocks Na channels in cardiac cells thus depolarization slows & decreases automaticity

(Lidocaine) Ind: Contra: Effects:

= Stable monomorphic VT w/ preserved LVF & Alternative to Amiodarone in cardiac arrest by VF/pVT = Shouldn’t use if PT already received IV Ca channel blockers, Not given prophylactically in AMI setting = Drowsiness, Slurred Speech, Confusion, Seizures, Hypotension

(Lidocaine) Max dose: Cardiac Arrest from VF/pVT dose: Refractory VF dose: Perfusing Arrhythmia dose: Maintenance Infusion dose:

= 3 mg/kg = 1-1.5 mg/kg IV/IO = may give additional 0.5-0.75 mg/kg IV/IO in 5-10 mins = 1-1.5 mg/kg IV/IO = 1-4mg/min (30-50 mcg/kg/min)

(Mag-Sulfate) Class: Dynamics:

= Misc. Airway med, Mineral, powerful noradrenergic bronchodilator = Organic Salt act as a physiologic Ca-channel blocker Bronchodilator

(Mag-Sulfate) Indi: Contra: Effects:

= PT not responding well to B2 adrenergic meds, Bronchial asthma, Torsades des pointes, Eclampsia = High-degree HB, Shock, Dialysis, Hypocalcemia, V-Fib/P-less, V-Tach = Flushing, Sweating, B-cardia, Resp/ depres/, Hypothermia

(Mag-Sulfate) Effects: Bronchodilation Adult Dose: Bronchodilation Pedi Dose:

= Flushing, Sweating, B-cardia, Resp/ depres/, Hypothermia = 1-2G IV/IO over 10-20 mins (Infusion) = 25-50 mg/kg IV/IO (max 2G) over 15-30 mins (Infusion)

(Narcan) Class: Dynamics: Indi: Contra: Effects: Dose:

= Competitive opiate antagonist = Finds & fights for opiate receptor spot = Dilated pupils & resp/ depres/ suspected from opiate OD = SBP<100 or DBP30<, SBP# drops 10/>, B-cardia (<50BPM), T-cardia (>100BPM), ingested ED meds in last 48 hours = H/A, Hypotension, = 0.4mg IN/IM w/ max 2ml

(NORepi) Class: dynamics:

= Synthetic hormone Vaso-pressor “Sepsis med” = A/B-adrenergic agonist (A effects > B effects)

(NORepi) Indi: Contra: Effects:

= Normovolemic hypotension, Septic shock, Cardiogenic shock = hypovolemia PTs til’ Vol/replacement occurred = Hypertension, Organ ischemia, Cardiac arrhythmia, Tissue necrosis w/ extravasation, Palpitations, Anxiety, N/V

(NORepi) Adult Dose: Pediatric Dose:

= 0.1–0.5 mcg/kg/min IV/IO infusion = 0.1–2 mcg/kg/min IV/IO infusion

(Solu-Medrol) Class: Dynamic: Indi: Contra:

= Synthetic pulmonary glucocorticoid Anti-inflammatory = Suppresses immune response = Bronchial asthma, COPD, Anaphylaxis = Hypersensitivity

(Solu-Medrol) Effects: Adult Dose: Pedi Dose:

= Increase BGL, delayed effects (rarely seen Pre-hospital) = 125-250 mg IV/IO = 2 mg/kg IV/IO to Max 60 mg

(Terbutaline) Class: Dynamics:

= Smooth muscle relaxer, Selective Sympathetic agonist = B agonist w/ relaxation of bronchospasm & Chronotropic effect< Epi

(Terbutaline) Indi: Contra: Effects: Dose:

= Asthma, Reversible airway obstruction from w/ bronchitis or emphysema, Preterm labor = hypersensitivity, PTs <12 years = Palpitations, Anxiety, Jitters, H/A, Dizziness, Tachycardia = 0.25mg IM

6 mg & 12mg rapid IV/O push followed w/ rapid flush of fluid)MED:

= Adenosine

2.5 mg/3 mL SVN every 15-20 minutes as needed)MED & 1.25-2.5 mg/1.5-3 mL SVN every 15-20mins as needed)MED

= Albuterol (adult) (PEDI)

2.2 grams Max & Med: 360 mg IV 6Hrs (1mg/min) for: 540 mg IV 18Hrs (0.5 mg/min) for: 1st Dose: 300 mg IVP & 2nd Dose:150 mg if needed for: 1st Dose: Rapid Infusion 150 mg/10 mins (15 mg/min) & 2nd Dose 150mg/10 mins (15 mg/min) if needed for:

= (Amiodarone) & max infusion dose =Slow Infusion dose =Maintenance Infusion dose = VF/Pulseless & VT Cardiac Arrest Unresponsive 1st & 2nd Dosage = Life-Threatening Arrhythmia 1st Dosage & Life-Threatening Arrhythmia 2nd Dosage

1 mg IVP every 3-5 minutes as needed, max 3 mg: 1 mg IVP every 3 minutes: dose: 2-4 mg IVP or more

= (Atropine) Normal bradycardia = Severe Clinical Conditions dose = organophosphate poisoning

500 mcg/2.5 mL via nebulizer FOR MED 250-500 mcg/1.25-2.5 mL via nebulizer FOR

(Ipratropium (Atrovent) Adult PEDI

25G IV/IO or D10 in 50 mL IV boluses (max 250mL) FOR MED 5-10 mL/kg of D10 FOR

(Dextrose) Adult Pedi

0.25 mg/kg (max dose 20 mg) FOR MED 0.35 mg/kg (max dose 25 mg) FOR=

(Diltiazem) 1st 2nd

2-20 mcg/kg/min IV infusion, titrate to effect 5-10 mcg/kg/min 10-20 mcg/kg/min

(Dopamine) dose range Cardiac dose Vaso-pressor dose

1 mg IVP/IO every 3-5 minutes FOR 2-10 mcg/min IV/IO infusion FOR 0.01 mg/kg IV/IO FOR 0.1-1 mcg/kg/min IV/IO infusion FOR

(EPI 1:10, ) Cardiac arrest = Adult Bradycardia dose = Pedi Bradycardia/Cardiac Arrest dose: = Pedi Hypoperfusion & Anaphylaxis dose

0.3 mg & up to 0.5 mg IM> FOR 0.01 mg/kg IM, (max 0.3 mg) FOR

(EPI 1:1, ) (asthma/COPD) & (anaphylaxis) PEDI

1 mg IM/IN> FOR >20 kg 1mg IM/IN & <20 kg 0.5 mg IM/IN> FOR

(Glucagon) hypoglycemia PEDIs

1-1.5 mg/kg IV/IO (Max 3mg) 0.5-0.75 mg/kg IV/IO in 5-10 minutes 1-1.5 mg/kg IV/IO 1-4 mg/min (30-50 mcg/kg/min)

(Lidocaine) Cardiac Arrest from VF/pVT dose Refractory VF additional dose Perfusing Arrhythmia dose: Maintenance Infusion dose:

1-2G IV/IO 10-20 mins 25-50 mg/kg IV/IO 15-30 mins(max 2G)15-30 mins

(Mag-Sulfate) Adult Bronchodilation dose: Pedi Bronchodilation dose:

0.1–0.5 mcg/kg/min IV/IO infusion 0.1–2 mcg/kg/min IV/IO infusion

(NORepi) Adult Pedi

125-250 mg IV/IO (Max 60 mg) 2 mg/kg IV/IO

(Solu-Medrol) Adult PEDI

0.25mg IM

(Terbutaline)

PHARM list Final Drugs Flashcards

(56 cards)