Pharm- Micro Flashcards
1
Q
NRTI
A
Inhibit nucleotide Binding to reverse transcriptase
they lack 3’ OH group
2
Q
Oseltamivir (Ivir)
A
Inhibit neuraminidase decreasing progeny virus
3
Q
Acyclovir (CLOVIR)
A
Guanosine analog
DNA POLIMERASE
4
Q
Antiviral used in herpes zoster
A
Famciclovir
5
Q
Foscarnet
A
DNA/ RNA POL doesn’t need to be activated
PyroFOSfate analog
6
Q
Protease inhibitor (NAVIR)
A
Virion depends on HIV protease
7
Q
Enfuvirtide
A
Inhibit gp41 (Fusion)
8
Q
Maraviroc
A
Binds CCR5 inhibiting interaction with gp120
9
Q
Amphotericin B
A
Ergosterol binding. Forms a pore
10
Q
Treatment for cryptococcus meningitis
A
Flucytosine
11
Q
Azoles
A
Inhibit ergosterol blocking P-450
12
Q
Terbinafine
A
Inhibit squalene epoxidase
13
Q
Griseofulvine
A
Microtibule formation
14
Q
Caspofungin
A
Synthesis of B- glucan
15
Q
Toxoplasmosis treatment
A
Pyrimethamine
