PHARM STUDY GUIDE Chapters 1, 2,3,5 Flashcards

(60 cards)

1
Q
Generic Name (Acetylsalicylic-)      
What is Trade Name?

Classification for Acetylsalicylic

A

Bayer-Aspirin •Bufferin

Platelet aggregator inhibitor, Nonsteroidal anti-inflammatory

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2
Q
Generic name (Adenosine)      
What is Trade name?

Classification for Adenosine

A

Adenocard

Antidysrhythmic

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3
Q
Generic Name (ALBUTEROL)     
What is Trade Name?

Classification for ALBUTEROL

A

Proventil -Ventolin

Sympathomimetic-Bronchodilator-Beta2 agonist

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4
Q
Generic Name (AMIODARONE)     
What is Trade Name?

Classification for AMIODARONE

A

Cordarone

Anti-dysrhythmic

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5
Q
GENERIC NAME (ATROPINE)     
What is Trade Name?

Classification for (ATROPINE)

A

NONE

Anticholinergic •Parasympathetic blocker• Antidote

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6
Q
Generic Name (CALCIUM CHLORIDE)     
What is Trade Name?

Classification for (CALCIUM CHLORIDE)

A

NONE

Electrolyte

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7
Q
Generic Name (ACTIVATED-CHARCOAL)    
 What is Trade Name?

Classification for (ACTIVATED-CHARCOAL)

A

Actidose •EZ-Char •Liqui-Char®

Adsorbent

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8
Q
Generic Name (DEXTROSE)      
What is Trade Name?

Classification for (DEXTROSE)

A

D50

•Carbohydrate• Antihypoglycemic

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9
Q
Generic Name (DIAZEPAM)       
What is Trade Name?

Classification for (DIAZEPAM)

A

Valium

•Benzodiazepine• Anticonvulsant• Sedative• Hypnotic

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10
Q
Generic Name (DILTIAZEM)      
What is Trade Name?

Classification for (DILTIAZEM)

A

Cardizem

•Calcium channel blocker•
Anti-dysrhythmic

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11
Q
Generic Name(DIPHENHYDRAMINE)    
 What is Trade Name?

Classification for (DIPHENHYDRAMINE)

A

Benadryl

•Antihistamine• Anticholinergic

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12
Q
Generic Name (DOPAMINE)       
What is Trade Name?

Classification for (DOPAMINE)

A

Intropin

•Sympathomimetic• Vasopressor Adrenergic agonist

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13
Q
Generic Name (EPINEPHRINE)     
What is Trade Name?

Classification for (EPINEPHRINE)

A

Adrenalin

Sympathomimetic

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14
Q
Generic Name (ETOMIDATE)      
What is Trade Name?

Classification for (ETOMIDATE

A

Amidate

Anesthesia induction agent• Hypnotic•Sedative

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15
Q
Generic Name (FENTANYL)      
What is Trade Name?

Classification for (FENTANYL)

A

Duragesic®•Sublimaze®

Narcotic analgesic• Narcotic agonist

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16
Q

What is Definition of PHARMACOKINETICS

A

refers to how the body acts on a medication,
including how the drug is absorbed into the bloodstream,
how the drug is distributed,
how the body metabolizes, and how the body eliminates the drug.

(WHAT THE BODY DOES TO THE DRUG)

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17
Q

What is Definition of PHARMACODYNAMICS

A

How a drug works and interacts with various receptors, other drugs and enzyme systems within the body.

(WHAT THE DRUG DOES TO THE BODY)

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18
Q

What is Definition of PHARMACOLOGY

A

Study of biochemical and physiologic properties of medications

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19
Q

What is Definition of THERAPEUTIC INDEX (TI)

A

is the measurement of the relative safety of a drug.
TWO factors used to determine safety of a drug.

EFFECTIVE DOSE AND LETHAL DOSE.

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20
Q

What is Definition of BIOAVAILABILITY

A

is the percentage of an administered drug that is available in the blood stream to act at the target tissue

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21
Q

6 PATIENTS RIGHTS

A
Right Patient, 
Right Drug/Right Indication
Right Dose
Right Route
Right Time
Right Documentation
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22
Q

What is a Side Effect?

A

Benign annoyances

Headaches
Nausea
Drowsiness

Often treated by reducing dosage or eliminating offending medication

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23
Q

Enteral administration

A

Absorbed through GI tract
Given orally or rectally
Must first pass through liver before being
distributed THROUGHOUT the body.

THINK ABOUT YOUR GROSS AND NET PAYCHECK

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24
Q

Parenteral Route

A

Medications are drugs that bypass the GI tract.
Rapidly available and circulate throughout body in minutes

IV is preferred route for cardiac medications in ALS situations

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25
Half life
Time required for concentration of medication in bloodstream to decrease to half its original level.
26
Duration of action
Amount of time a single dose produces desired effect
27
buccal administration
absorption across mucous membranes or the skin Example glucose gel
28
What are some common causes of (ALOC)?
``` Cardiac arrhythmia Diabetic emergency SeizureToxic ingestion or overdose StrokeTraumatic brain injury ```
29
generic
Registered with Food and Drug Administration (FDA) Pharmacopeia-National (Written in lower case)
30
Trade Name
Created by pharmaceutical companies Always (begin with a capital letter)
31
First pass metabolism
Drug is partially metabolized Reduces amount of medication THINK ABOUT YOUR GROSS AND NET PAYCHECK
32
Passive diffusion
Occurs when medications penetrate cells by diffusing through cells membranes Think of breathing!
33
Passive transport
Occurs when drug molecule moves down concentration gradient Drug moves from area of high concentration to area of low concentration
34
Receptors
Are sites on various tissue to which some drugs bind to exert their desired physiologic effects. Think about a key and lock. The DRUG is the key. The RECEPTOR is the lock.
35
Absorption
is the movement of a medication from the point of administration. Example ( GI tract skin muscle) into the bloodstream for movement throughout the body.
36
Drug excretion
Removal of drug or metabolite from body Kidney is typically the organ responsible for removal
37
Onset of action
Time interval from administration to desired effect
38
Reversible binding
Occurs when drug is able to separate from cell’’s receptors When drug is removed from receptor, effect of drug stops
39
Irreversible binding
Some medications are unable to separate from receptor after they bind to receptor they bind to receptor. ASA PLAVIX MAOI’’s
40
Agonist
Drug that produces desired physiologic effect upon binding with receptor Turn things on
41
Antagonist
Drug that diminishes or eradicates physiologic effect of agonist Turn things off
42
Adverse effects
Considered serious Renal failure Bleeding Bone marrow suppression Progression of heart disease
43
Cholinergic agonists
Drugs that act on the parasympathetic nervous system.
44
adrenergic agonists
Medications that exert effects on the sympathetic nervous system.
45
Beta 1 receptors
Cardiovascular in nature they are found on the heart. increase heart rate and contractility. Increases cardiac output
46
Beta 2 receptors
located on the bronchial smooth muscle. increases the diameter of the bronchial tree. Stimulation relaxes bronchial smooth muscle (Respiratory emergencies)
47
Alpha1
Primarily located on peripheral blood vessels Stimulation results in vasoconstriction and elevation systemic BPs
48
Alpha2
Located on nerve endings Provide negative feedback to nerves in sympathetic nervous system Signals process when goal or target is reached
49
Sympathomimetic
physiological effects characteristic of the sympathetic nervous system by promoting the stimulation of sympathetic nerves.
50
Chronotropic
EFFECTS THE HEART RATE POSTIVE INCREASES NEGATIVE DECREASES
51
INOTROPIC
EFFECTS THE SQUEEZE OF THE HEART MUSCLE POSTIVE MAKE SQUEEZE HARDER NEGATIVE DECREASE THE INTENSITY OF CARDIAC SQUEEZE
52
ISOTONIC
Fluids that have equal osmotic pressure with the body under normal conditions.
53
HYPOTONIC
Fluids that have less osmotic pressure.
54
HYPERTOMIC
Fluids have greater than normal osmotic pressure,
55
MICRO DRIP
Administer 60 gtt/mL Used with adrenergic agents and cardiac anti-arrhythmics Used with children sensitive to large amounts of IV fluids
56
MACRO DRIP
Variety of sizesDrip factors of 10, 12, 15, and 20 gtt/mL
57
For any amount of blood loss,
You need at least 3x amount of crystalloid | is required to increase intravascular volume to compensate.
58
Intracellular fluid (ICF)
Found inside cells
59
Extracellular fluid (ECF)
Found between cells and inside blood vessels
60
Active transport
Requires macromolecule to assist in transport | Capable of reaching point of saturation.