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Pharma1 Flashcards

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1
Q

Directly acting cholinergic drugs

A
  1. Metaholine
  2. Carbachol
  3. Betanechol
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2
Q

Reversible inhibitors Indirectly acting cholinergic drugs

A
  1. Edrophonium
  2. Physostigmine
  3. Neostigmine
  4. Pyridostigmine
  5. Rivastigmine
  6. Galatamine
  7. Donepezil
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3
Q

Mydriatics

A
  1. Cyclopentolate
  2. Tropicamide
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4
Q

Asthma antimuscarinic agent

A

Aclidin

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5
Q

Myesthenia gravis Ntimuscarinic agent

A

Glycopurronium

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6
Q

Motion sickness antimuscarinic agent

A

Scopolamine

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7
Q

Antipsrkinsonian antimuscarinic agents

A

Biperiden
Procycline

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8
Q

Antiheroentensive alpha blockers

A

Prazosine
Terazosine
Doxazosine
Urapidil

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9
Q

Mixed action a and B blockers

A

Labetalol-> pregnancy
Phenoxhbenzamine

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10
Q

Benign prostate hyperthrophy

A

Alfuzosine
Tamsulosine
Silodosin

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11
Q

Ergot alkaloids

A

Ergotamin-> partial a1 stimulant
Nicergoline -> post stroke

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12
Q

a1,a2 direct acting agonist

A

Oxymetazoline

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13
Q

B1,B2 direct acting agonist

A

Isoproterenol

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14
Q

a1 agonist

A

Phenylephrine

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15
Q

a2 agonist

A
  1. Clonidine
  2. Guanfacine
  3. a-methyl-DOPA
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16
Q

B1 agonist

A

Dobutamin

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17
Q

B2 agonist

A
  1. Terbutaline
  2. Albutetol
  3. Salmeterol
  4. Formoterol
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18
Q

B3 agonist

A

Mirabegron

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19
Q

Mixed acting symphatomimetic

A

Ephedrine

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20
Q

COMT inhibitor

A

Entacapone
Tolcapone

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21
Q

Cardio selective beta blockers

A
  1. Atenolol
  2. Esmolol
  3. Metoprolol
  4. Bisoprolol
  5. Nebivolol
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22
Q

Non selective beta blocking agents

A
  1. Propranolol
  2. Sotalol
  3. Timolol
  4. Carvedilol
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23
Q

Zero order elimination drugs

A

Phenytoin
Aspirin
Ethanol

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24
Q

Long elimination half life

A

Digitoxin
Digoxin
Amidarone
Morphine

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25
Non depolarizing muscle relaxants: long duration of action
1. D-tubocurarine 2. Pancuronium 3. Pipecuronium
26
Non depolarizing muscle relaxants -> intermediate duration
Atracurium Rocurium
27
Non depolazing muscle relaxant -> short duration of action
Mivacurium
28
Beta blocker with intrinsic symphatomimetic activity
Pindolol
29
COX2 inhibitors
Celecoxib Diclofenac Meloxicam Etoricoxib
30
Non inhalational glucocorticoids
Hydrocortisone Prednisolon Dextametasone
31
Inhalational glucocorticoids
Budesonide Fluticasone
32
Treatment of asthma with B2 symphatomimentics
Short -> salbutamol Long-> formoterol Ultralong -> indacaterol
33
Inhalational glucocorticoids for asthma
1. Budesonide 2. Ciclesonide 3. Fluticasone 4. Mometazone
34
Long acting bronchodilator b2 agonist
Formoterol Salmeterol
35
Mucosal protective agents
Carbenoxolone Sucralfate Bismuth
36
D2 receptor blockers
Metoclopramide Domperidone Cisaprid
37
Factor Xa inhibitors poisoning
AndeXanet alpha
38
Cholinesterase inhibitors poisoning treatment
Atropine Pralidoxime
39
Triptans
Suma Ele Nara Riza Almo
40
Migraine status
Prednisone Dexamethasone
41
Migraine therapy in combination with antiemetics
Metoclopramide Domperidone
42
Migraine prophylaxis
Beta blockers Valproate Topiramate Amitryptiline Flunarizine
43
Chronic migraines new medication
CGRP antagonist -> Gepant Serotinergic agonist-> lasmiditan
44
CGRP targeting monoclonal antibodies for migraine
Eptine zumab Fremane zumab Galcane zumab
45
HMV-COA reductase inhibitors
Lovastatin Simavastatin Atorvastatin
46
LPL activators
Bezafibrat Gemfibrozil
47
Nicotinic acid
Acipimox Blocks hormone sensitive lipase
48
PCSK9 inhibitors
Alirocumab Evolocumab
49
MTTP inhibitors
Lomitapid Decrease LDL,VLDL
50
Resins
Cholestyramin Cholesevelam Cholestipol
51
Phosphodiesterase 3 inhibitors
Amirinone Milrinone
52
Ca sensitizing agent
Levosimendan Vasodilatory
53
Anti-influenza
1. Proton channel inhibitor -> amantadine 2. Endonuclease inhibitor -> balovaxir 3. Neuraminidase inhibitor -> zanamivir
54
Entry inhibitor anti-HIV
Enfuvirtide Maraviroc
55
Nucleoside reverse transcriptase inhibitor
Zidovudine
56
Non nucleoside reverse transcriptase inhibitor
Nevirapine Efavirenz
57
Integrase inhibitor HIV
Raltegravir
58
Protease inhibitor
Ritonavir
59
HBV treatment
IFN-a 2a-> activation of ribonuclease Adefovir -> DNA polym Lamivudine -> inhibits DNA polymerase
60
Centerally acting muscle relaxants
Tizanidine Baclofen Diazepam Guaifenesin Cyclobenzaprine Chlorzoxazone
61
MAO-B inhibitors
Selegilin Rasagiline
62
Dopamine agonists
Ergot-> bromcriptine Non-ergot -> pramipexole
63
Alzheimer’s disease
NMDA inhibitor -> memantine Cholinestwrase inhibitor -> rivastigmine Selegiline Vinpocetine
64
Sulfonamides
Sulfamethoxazole Sulfadiazine Sulfazaline
65
Generations of quinolones
1-> nalidixic acid 2-> nordloxacin 3-> levofloxacin 4-> delafloxacin
66
Antiepileptic working on presynaptic
1. Gabapantin-> ca 2. Lamotrigin -> ca 3. Carbamazepine -> na 4. Phenytoin -> na 5. Retigabin -> k
67
Anti epileptic medication working on post synaptic neurons
Felbamate-> NMDA Topiramate -> AMPA Valporate -> ca
68
GABA enhancers
Phenobarbital Diazepam Clonazpam Tiagabine Vigabatrin
69
estrogen antagonits
receptor dowregulator-> clomiphene receptor mediator-> tamoxifen aromatase
70
Progesterone agonists
1. Progesterone 2. Medroxyprogesterone 3. Levonorgestrel
71
progesterone antagonis
mifepristone ulipristal
72
testosterone antagonists
1. flutamide 2. finasteride ->5a reductase in 3. abiraterone-> 17a reducatse in 4. ketoconazole
73
oral contraceptives
diethynyl estradiol + levonorgestrel ulipristal
74
SSRI
Sertraline Fluoxetine Paroxetine Citalopram Escitalopram
75
Tetracycline
Amitriptyline Imipramine
76
SNRIs
Duloxetine Venlafaxine
77
MAO inhibitor
Non selective -> phenelzine Reversible NE-> moclobemide Irreversible DA -> selegiline
78
Other anti depressants
Maprotilin-> tetracycline Bupropion-> inh reputake Mirtazapine-> a2 inhibitor
79
Inhalational anasthesia
Diethyl ether Halothane Isoflurane Sevoflurane Desflurane Dinitrogen oxide
80
Intravenous anesthesia
Barbiturates -> thiopental Benzodiazepines->midozolam Propofol Etomidate Ketamine
81
Pre medication for surgery
Diazepam Atropine Ranitidine Omeprazole
82
Post surgery medication
Neostigmine Naloxon
83
Insulin types
1. Rapid -> aspart 2. Short -> insulin 3. Intermediate -> NPH 4. Long -> detemir 5. Combined -> humulin
84
Emetics
Apomorphine Ipecac
85
Antiemetics
1. Serotonin AT 2. Corticosteroids 3. Neurokinin 1 AT 4. Phenothiazines 5. Butyrophenones 6. Benzamides 7. Anti histamin 8. Muscuranic AT 9. Benzodiazepines 10. Cannabinoids
86
Serotonin antagonist
Ondansetron Granisetron Dolasetron
87
Neurokinin 1 antagonists
Ap repitant Fosap repitant
88
Sulfonylureas
Glibenclamide Glimepiride
89
oral antidibetic drugs
1. sulfonylureas 2. meglitidines->repaglindines 3. thiazoidindiones 4. biguanides 5. a-glucosidase inhibitors 6. SGLT2 in-> dopagliflozin 7. DPP inhibitor-> sitagliptin
90
Methanol intoxication
Femopizol Thiamine Disulfiram
91
Novel oral anti coagulant
Factor 10 inhibitors -> apixaban Factor 2 inhibitor -> dabigatran
92
Usage of arsenic medication
Trisenox-> acute promyelocyric leukemia Melarsopol-> sleeping sickness
93
Treatment of arsenic poisoning
Dimercaprol
94
Iron toxicity therapy
Deferoxamine- magnesium hydroxide solution
95
Cyanide poisoning therapy
Sodium nitrate Sodium thiosulfate Hydrocobalalamin Methylene blue
96
Esters local anesthetic
Procaine Cocaine Tetrcaine Benzocaine Chloroprocaine
97
Amide local anesthetic
Lidocaine Articaine Bupivacaine Ropivacaine
98
Mushroom poisoning
Amantina phalloides Inocybe-> muscarine Amantina muscarina-> GABA, NMDA Magic mushroom Hourse mushroom
99
Calcium channel blockers
Verapamil Diltiazem
100
Angiotensin 2 receptor blockers
Lo sartan Val sartan
101
ACE inhibitors
Captopril Enlapril Rami pril
102
Renin inhibitors
Aliskiren
103
paracetamol intoxication therapy
N-Acetylcysteine
104
Ca channel blockers
Nifedipine Amlodipine Verapamil
105
Antidote of benzodiazepines
Flumazenil
106
Volume of distribution
Dose/ concentration at time 0
107
Half life
0.7* volume of distribution/ clearance
108
Maintenance dose
Clearance* steady state concentration* dosing interval/ bioavailability
109
Loading dose
Volume of distribution* CC in plasma/ bioavailability
110
Directly acting arterial vasodilators
1. Hydralazine 2. Sodium nitro prusside 3. Minoxidil
111
Imidazoline receptor agonists
Moxonidine Rilmenidine
112
K sparing drugs
1. Spironolactone 2. Eplerenone 3. Amiloride 4. Triamterene
113
Endothelin receptor antagonists
Bosentan Ambrisetran
114
SGLT-2inhibitors
Dapagliflozin Empagliflozin
115
Alpha glocosidase inhibitors
Acarbose Miglitol
116
Proton pump inhibitors
Omeprazole Pantoprazole
117
GERD drugs
D2 blockers -> metoclopramide 5HT4 agonist-> mosapride Muscatunic agonist-> betanechol Macrolide -> erythromycin
118
Gall bladder stone drug
Chenofalk Ursofalk
119
Pancreatic enzyme deficiency
Cotazym Creon
120
Class 1A antiarythmic
Quinidine Procainamide Disopyramide
121
Class IB antiarrthmic drugs
Lidocaine Mexiletine Phenytoin
122
Type I/C antiarythmic drugs
Flecainide Propafenone
123
Class 3 antiarythmic
Amiodarone Ibutilide Dronedarone Sotalol
124
First generation antihistamine
Diphenhydramine Dimenhydrinate Chloropyramine
125
Second generation antihistamine
Cetirizine Loratadine Rupatadine
126
3rd generation antihistamin
Levocitrizine Desloratadine Fexofenadine
127
Calcium sensing receptor sensitizer
Cinacalcet
128
Estrogen replacement therapy for osteoporosis
Tibolone Raloxifene
129
Anti RANKL antibody
Denosumab
130
Bisphosphonates
Alendronate Risendronate Clodronate AE: esophagitis
131
132
Antifinrinolytic drugs
Epsilon amino-caproic acid Tranexamic acid
133
Drugs for thrombocytopenia
Romiplostim
134
Hemochromatosis drug
Deferoxamine IV
135
Megaloblastic anemia drugs
Cyanocobalamin Hydroxocobalamin
136
Sickle cell anemia drug
Hydroxyurea
137
Chronic coronary syndrome 2nd line drugs
1. Ivabradine 2. Ranolazine-> na 3. Nicorandil -> k 4: trimetazidine
138
Cytochrome p459 inhibitors
Amidarone Flucunazole Metronidazole Sulphomethazalone Trimethoprim
139
P2y12 receptor inhibitor
Ticagrelor Prasugrel Clopidugrel
140
GP IIaIIIb inhibitor
Tirofiban Abciximab

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