Pharmac

Question 1

Grape juice and

Answer 1

Statins

Juice contains Cyp 450 inhibitors

Question 2

Mecamylamine

Answer 2

Ganglion ach blocker

Question 3

Vd

Answer 3

Dose / Co

Question 3

t1/2

Answer 3

0.7 x Vd / Cl

Question 4

Infusion rate (ko)

Answer 4

Cl x Css

Question 5

Loading dose

Answer 5

Vd x Cp / f

Question 6

Maintanence doss

Answer 6

f

Question 7

Fenoldopam

Answer 7

D1 agonist - used in severe hypertension

Question 8

Beta blocker with least sedation

Answer 8

Atenolol

Question 9

Beta blocker which also bronchodilates n least effect on lipids

Answer 9

Pindolol (partial agonist)

Question 10

DOC in pheochromocytoma

Answer 10

Phenoxybenzamine (non selective , non competitive alpha blocker)

Question 11

Sympathetic drug in shock

Answer 11

Dopamine
D1 -> b1 -> a1
Low dose -> high dose

Question 12

Class 1A antiarrythmic

Answer 12

Fast sodium channel - open state

Quinidine , procainamide

Question 13

Class 1B Antiarrythmic

Answer 13

Blocks fast sodium channel (inactive shape)

Lidocaine
Mexiletine n tocainaide (oral)

Post MI

Question 14

Class 1C antiarrythmic

Answer 14

Flecainamide (last stage drug)

Question 15

Class 2 antiarrythmic

Answer 15

Decreases AV nodal conduction

Propranolol, esmolol, acebutalol

Question 16

Class 3 antiarrythmic

Answer 16

Delayed rectifier Potassium channel blocker

Amiodarone (iodine)
sotalol

Question 17

Class 4 antiarrythmic

Answer 17

Decreases AV nodal conduction

CCB - verapamil, diltiazem

Question 18

Nalbuphine, pentazocine

Answer 18

Mixed partial OPIOD agonist

Question 19

Naloxone

Answer 19

IV opioid antagonist

Reversal of morphine toxicity and resp depression

Question 20

Naltrexone

Answer 20

Oral opioid antagonist

Decrease craving in alcoholics and opioid addicts

Question 21

Opioid withdrawal Mx

Answer 21

Methadone and clonidine ( decreasing the excessive SANS )

Question 22

Meperidine

Answer 22

Pethidine

Mu opioid agonist WITHOUT ANTIMUSCARINIC effect

Question 23

Varenicline, bupropion

Answer 23

Smoking cessation

Varen - partial agonist of nicotine receptor
Bupro - dopamine reuptake blocker

Question 24

drugs for ADHD

Answer 24

Amphetamine - methylphenidate | Selective NE reuptake inhib - Atomoxetine

Question 25

Dabigatran | Protamine sulfate

Answer 25

???

Question 26

Nifurtimox

Answer 26

Treat Chagas' disease (trypanosomiasis)

Question 27

Aprepitant

Answer 27

Neurokinin antagonist : anti emetic

Question 28

Ondransetron

Answer 28

5HT3 antagonist | Strong anti emetic

Question 29

Metoclopromide

Answer 29

D2 antagonist | Anti emetic n pro kinetic

Question 30

Alprostadil

Answer 30

PGE 2 agonist - maintains PDA

Question 31

Canagliflozin

Answer 31

SGLT 2 inhibitor : increase glucose excretion

Question 32

Pramlintide

Answer 32

Synthetic amylin

Question 33

Leuprolide

Answer 33

Testosterone blocker