Pharmaceutical toxicology Flashcards

1
Q

What is toxicology

A

Is the study of the harmful effects of chemical , biological and physical substances on biological systems

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2
Q

It can be divided into

A

Environmental
Forensic
Food
Occupational
Clinical

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3
Q

Environmental toxicology

A

Is the study of the harmful effects of manmade and natural chemicals on living organisms and environment

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4
Q

What is toxic substances control act

A

Is a federal law that regulates industrial chemicals that have the potential to be harmful to humans and the environment

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5
Q

The clean air act

A

Aims to reduce acid,ozone layer, improving the air quality and toxic pollutants

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6
Q

Occupational toxicology

A

Application of toxicology towards chemical and biological hazards in the workplace

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7
Q

Forensic toxicology

A

The determination of drug use , poisoning as part of a legal investigation

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8
Q

Food toxicology

A

Study of the nature , effects of toxic substances in food and their disease manifestation in humans

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9
Q

Clinical toxicology

A

deals with the identification of chemicals ,drugs or toxins that may affect patients

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10
Q

Preventive measures for poisons

A

Keep household chemicals locked and stored away
Meds should be taken as directed
Provisions of SOPs for handling and disposal of hazardous substances

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11
Q

Treatment of acute poisoning

A

If ingested then use emesis to remove poison but avoid if patient is drowsy,delirious etc

If absorbed then give activated charcoal

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12
Q

Common examples of poison

A

Drugs

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13
Q

Treatment of inhaled poison

A

Give artificial respiration

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14
Q

Treatment of acute poisoning in the hospital

A

Give supportive and symptomatic treatment
Administer antidote where possible
Lower conc of poison in the vital tissues

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15
Q

What is Adverse drug reaction

A

It is when an unintended response to a drug occurs at a dose normally given.

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15
Q

Symptomatic treatment includes

A

Management of CNS depression
Improvement of respiration
Treatment of convulsion with diazepam
Normalization of BP and body temp

16
Q

What is drug toxicity?

A

Accumulation of excess drug in the system

17
Q

Toxic side effects of paracetamol

A

It causes hepatotoxicity

18
Q

What is extra pirimidal side effects,CNS and anticholinergic side effects

A

Anticholinergic-
CNS-
Extra pirimidal side effects-anti Parkinson drugs,muscle spasms, stiffness, acute dystonia

19
Q

What is used to induce vomitting?

A

EPECACUANHA

20
Q
A
21
Q
A