pharmacology

Question 1

what is penicillin

Answer 1

penicillin is a beta lactam antibiotic

Question 2

what is the clinical use for pencillins

Answer 2

Streptococcal infections
Pneumococcal infections
Gonococcal infection
Meningococcal infection
Treponema (syphilis)
Clostridium (tetanus, gas gangrene)
Diptheria, anthrax, leptospirosis

Question 3

adverse effects of broad spectrum penicillins

Answer 3

hypersensitivity reations such as anaphylaxis, rashes, hepatitis and cholestatic jaundice

Question 4

what is a broad spectrum penicillin (aminopenicillin)

Answer 4

Streptococcal infections
Pneumococcal infections
Gonococcal infection
Meningococcal infection
Treponema (syphilis)
Clostridium (tetanus, gas gangrene)
Diptheria, anthrax, leptospirosis

Question 5

clinical uses for broad spectrum penicillin (aminopenicillin)

Answer 5

Exacerbations of chronic bronchitis and middle ear infections

Prophylaxis for endocarditis
or in combination with gentamicin for E. faecalis endocarditis

Question 6

what can be some side effects of penicillins

Answer 6

Nausea, Diarrhoea, Thrush, Headache
Allergic reactions – itching, rash, swollen lips and tongue, anaphylaxis – 15% of population are documented to have a penicillin allergy
Hairy black tongue (rare)