Pharmacology Flashcards

(55 cards)

1
Q

What are the mechanisms through which drugs are processed by the body?

A

Liberation, Absorption, Distribution, Metabolization, Excretion

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2
Q

What is the first mechanism when a drug is processed by the body?

A

Liberation

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3
Q

What is the second mechanism when a drug is processed by the body?

A

Absorption

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4
Q

What is the third mechanism when a drug is processed by the body?

A

Distribution

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5
Q

What is the fourth mechanism when a drug is processed by the body?

A

Metabolization

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6
Q

What is the final mechanism when a drug is processed by the body?

A

Excretion

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7
Q

What is the mechanism for when the drug separates from the inactive ingredients?

A

Liberation

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8
Q

What is liberation?

A

The mechanism through which a drug separates from inactive ingredients

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9
Q

Complete the list:

_______ > Absorption > Distribution > Metabolism > Excretion

A

Liberation

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10
Q

What is the mechanism for when the drug begins entering the blood?

A

Absorption

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11
Q

What is absorption?

A

When the drug enters the blood

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12
Q

What is bioavailability?

A

The percentage of a drug that actually enters the blood

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13
Q

What is the term for the percentage of a drug that actually enters the blood?

A

Bioavailability

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14
Q

What reduces a drug’s bioavailability?

A

When a drug has to pass through the mucous membranes and GI tract

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15
Q

What can be changed about a drug to change its onset and duration of action?

A

Liberation

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16
Q

What type of drugs are subject to the first-pass effect?

A

Drugs taken orally

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17
Q

What is the first-pass effect?

A

The breakdown of drugs before they reach circulation

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18
Q

What is the term for the breakdown of drugs before they reach circulation?

A

First-pass effect

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19
Q

What is the mechanism where a drug becomes dispersed around the body?

A

Distribution

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20
Q

What is distribution?

A

When a drug becomes dispersed around the body

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21
Q

Complete the list:

Liberation > _______ > Distribution > Metabolism > Excretion

A

Absorption

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22
Q

What is Metabolism?

A

The breakdown of a drug

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23
Q

What is the mechanism for when the body breaks down the drug?

24
Q

Complete the list:

Liberation > Absorption > Distribution > ______ > Excretion

25
What is excretion?
Elimination of a drug from the body
26
What is the mechanism for when a drug is eliminated from the body?
Excretion
27
Complete the list: Liberation > Absorption > Distribution > Metabolism > __________
Excretion
28
What is elimination half-life?
The time required for the drug to reach half of its peak concentration
29
What are the two ways a drug acts on bodily systems?
Mimicking or inhibiting normal processes in the body and inhibiting the growth of certain organisms
30
What is an agonist?
Binds to receptors and stimulates activity
31
What is an antagonist?
Binds to a receptor to block activity
32
What is a patrial agonist?
Agonists that partially activate receptors
33
What is an inverse agonist?
Agonists that slow activity
34
What is the mechanism of action for when a drug binds to receptors and stimulates activity?
Agonist
35
What is the mechanism of action for when a drug binds to a receptor and blocks activity?
Antagonist
36
What is the mechanism of action for when a drug partially activates receptors?
Partial Agonist
37
What is the mechanism of action for when a drug binds to a receptor to slow activity?
Inverse agonist
38
What is the duration of action?
How long a drug is effective
39
What is the term for how long a drug is effective?
Duration of action
40
What does DAW 0 mean?
No product selection is indicated and substitution is acceptable
41
What does DAW 1 mean?
Substitutions are not allowed by the prescriber
42
What does DAW 2 mean?
Patient is requesting brand name
43
In a DAW 1, who is requesting the brand name of the drug?
The prescriber
44
In a DAW 2, who is requesting the brand name of the drug?
The patient
45
What is a DAW 3?
Pharmacist has selected brand name, substitutions allowed
46
What is a DAW 4?
The generic brand is not in stock
47
Who is requesting the brand name in DAW 3?
The pharmacist
48
What is DAW 5?
Brand-name has been dispensed at the generic price, substitution allowed
49
What is DAW 6?
Override code
50
What is DAW 7?
Brand-name is mandated by law
51
What is a DAW 8?
Generic isn't available
52
What is the difference between DAW 4 and DAW 8?
DAW 4 is when the generic isn't in stock, DAW 8 is when it is not available
53
What do barbiturates do?
Depress the central nervous system
54
What do corticosteroids do?
Reduce inflammation
55
What is the expiration date for a drug?
Usually a month and a year