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GI II > Pharmacology > Flashcards

Pharmacology Flashcards

(95 cards)

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1
Q

Dexlansoprazole

A

Proton Pump Inhibitor

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2
Q

Esmeprazole (Nexium)

A

PPI

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3
Q

Lansoprazole (Prevacid)

A

PPI

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4
Q

Omeprazole (Prilosec)

A

PPI - may inhibt warfarin metabolism

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5
Q

Pantoprazole (Protonix)

A

PPI

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6
Q

Rabeprazole

A

PPI

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7
Q

Cimetidine (Tagamet)

A

H2 Receptor Antagonist

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8
Q

Famotidine (Pepcid)

A

H2RA

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9
Q

Nizatidine

A

H2RA

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10
Q

Ranitidine (Zantac)

A

H2RA

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11
Q

Sodium bicarbonate (baking soda, Alka Seltzer)

A

Antacids

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12
Q

Calcium carbonate (Tums)

A

Antacids

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13
Q

Magnesium hydroxide/Aluminum hydroxide (Mylanta, Maalox)

A

Antacids

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14
Q

Bismuth subcitrate

A

Mucosal Protection

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15
Q

Bismuth subsalicylate

A

Mucosal Protection (Pepto-Bismol)

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16
Q

Misoprostol

A

Mucosal Protection - prostaglandin analog

not well tolerated, not in pregnancy

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17
Q

Sucralfate (Carafate)

A

Mucosal Protection

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18
Q

Amoxicillian

A

Antibiotic for H. pylori

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19
Q

Clarithromycin

A

Antibiotic for H. pylori

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20
Q

Metronidazole

A

Antibiotic for H. pylori

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21
Q

Tetracycline

A

Antibiotic for H. pylori

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22
Q

5-aminosalicylic acid

A

IBD - first line for mild/moderate UC

ADR: nephrotox, lupus like, pancreatitis, hepatotox

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23
Q

Apriso, Asacol, Lialda, Pentasa

A

Delayed/extended release 5-aminosalicylic acid (IBD)

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24
Q

Sulfasalazine, balsalazide, slsalazine

A

Prodrug - 5-aminosalicylic acid (IBD)

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25
Rowasa, Canasa
Rectal formulations - 5-aminosalicylic acid (IBD)
26
Prednisone
Corticosteroid (IBD) inhibits inflammatory cytokines | moderate to severe IBD
27
Budesonide
Corticosteroid (IBD)
28
Hydrocortisone
Corticosteroid (IBD)
29
Azathioprine
Immunosuppressants (IBD) purine analog
30
Mercaptopurine (6-MP)
Immunosuppressants (IBD) purine analog
31
Methotrexate(MTX)
Immunosuppressants (IBD) - inhibits DHF reductase/ macrophages maintain remission of CD ADR: bone marrow, megaloblastic anemia, alopecia
32
Cyclosporine
Immunosuppressants (IBD)
33
Infliximab
Anti-TNF alpha antibody (IBD) inhibits calcineurin TNF key pro inflammatory cytokine severe CD severe infections, antibodies to antibody, serum sickness
34
Adalimumab
Anti-TNF alpha antibody (IBD)
35
Certolizumab pegol
Anti-TNF alpha antibody (IBD)
36
Natalizumab
alpha4-integrin Monoclonal Antibody (IBD)
37
Metronidazole
Antibiotics (IBD)
38
Ciprofloxacin
Antibiotics (IBD)
39
Lubiprostone
Laxatives (IBS)
40
psyllium, bran
Bulk forming laxatives (IBS)
41
Loperamide (Imodium)
Anti-Diarrheal Agents (IBS)
42
Diphenoxylate (Lomotil)
Anti-Diarrheal Agents (IBS)
43
Tegaserod - withdrawn
Prokinetic Agent (IBS)
44
Alosetron
5HT3 Antagonist (IBS)
45
Dicyclomine
Antispasmodic Agents (IBS) anticholinergics
46
Hyoscyamine sulfate
Antispasmodic Agents (IBS) anticholinergics
47
Amytriptyline
Antidepressants (IBS)
48
Peginterferon alfa
HBV/HBC drug - inhibits viral penetration/replication ADR flu like illness, neurotoxic (chronic use) CI hepatic decomposition and psychiatric disease
49
Adefovir
HBV drug - Nucleoside Analog inhibits DNA polymerase, PO ADR: HA diarrhea, ab pain, renal probs not first line
50
Entecavir
HBV drug - NA inhibit DNA polymerase first line
51
Lamivudine
HBV drug - Nuleoside analog inhibit DNA polymerase HIV, not first line
52
Telbivudine
HBV drug - NA inhibits DNA polymerase no use with interferon alfa not first line
53
Tenofovir
HBV drug - NA inhibits DNA polymerase ADR: decrease bone density first line
54
Ribavirin
HCV drug inhibits RNA initiation/elongation ADR: hemolytic anemia, teratogenic, oncogenic, gonadotoxic
55
Simeprevir
HCV drug | inhibits protease
56
Sofosbuvir
HCV drug | inhibits RNA polymerase
57
Boceprevir
HCV drug - Protease Inhibitors
58
Ondansetron (Zofran)
5-HT3 antiemetic
59
Granisetron
5-HT3 antiemetic
60
Dolasetron
5-HT3 antiemetic
61
Palonosetron
5-HT3 antiemetic
62
Metoclopramide
Substituted Benzamide - D2 receptor antagonist - antiemetic
63
Chlorpromazine
Phenothiazines - D2 Receptor Antagonists - antiemetic
64
Prochlorperazine
Phenothiazines - D2 Receptor Antagonists - antiemetic
65
Thiethylperazine
Phenothiazines - D2 Receptor Antagonists - antiemetic
66
Triflupromazine
Phenothiazines - D2 Receptor Antagonists - antiemetic
67
Cyclizine
Antihistamine - antiemetics
68
Dimenhydrinate (Dramamine)
Antihistamine - antiemetics
69
Diphenhydramine (Benadryl)
Antihistamine - antiemetics
70
Hydroxyzine
Antihistamine - antiemetics
71
Meclizine
Antihistamine - antiemetics
72
Promethazine
Antihistamine - antiemetics
73
Scopalamine
Antimuscarinics - antiemetics
74
Dronabinol
Cannabinoids - antiemetics
75
Aprepitant
Neurokinin Receptor Antagonist - antiemetic
76
Fosaprepitant
Neurokinin Receptor Antagonist - antiemetic
77
Dexamethasone
Corticosteroids - antiemetics
78
Methylprednisolone
Corticosteroids - antiemetics
79
Lorazepam
Benzodiazepines - antiemetics
80
Alprazolam
Benzodiazepines - antiemetics
81
Diazepam
Benzodiazepines - antiemetics
82
Loperamide (Imodium)
Opioids - Antidiarrheal agents
83
Diphenoxylate (Lomotil)
Opioids - Antidiarrheal agents
84
Difenoxin
Opiods - Antidiarrheal agents
85
Paregoric (camphorated opium tincture, morphine)
Opiods - Antidiarrheal agents
86
Octreotide acetate
Somatostatin analog - Antidiarrheal agents
87
Bismuth subsalicylate (Pepto-Bismol)
Mucosal Protective Agents - Antidiarrheal agents
88
Saline Laxatives
Osmotic Laxitive
89
Nondigestible sugars and alcohols
Osmotic laxitive
90
Polyethylene Glycol-Electrolytes
Osmotic laxitive
91
Stimulant Laxitives
Laxitives
92
Stool Softeners
Laxitives
93
Metoclopramide
Prokinetic Laxitive
94
Domperidone
Prokinetic Laxitive
95
Erythromycin
Prokinetic Laxitive

GI II (1 decks)

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