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Obsessive Compulsive Disorder > Pharmacology > Flashcards

Flashcards in Pharmacology Deck (13)
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1

Typical fluoxetine dose

20-80 mg daily

2

Typical fluvoxamine dose for OCD

150-300 mg daily

3

Typical sertraline dose for OCD

100-300 mg daily, even up to 400 mg

4

Typical paroxetine dose for OCD

20-80 mg daily

5

Typical citalopram dose for OCD

20-80 mg daily (exceeds Health Canada Guidelines)

6

EKG monitoring guidelines for citalopram / escitalopram for OCD

Monitor EKG, If QT-interval >440msec (in men) or >470msec (in women), but <500msec – reduce dose or switch to a lower risk drug (citalopram & escitalopram contra-indicated)
• If QT-interval >500msec – STOP citalopram/escitalopram and consider cardiology referral

7

Typical escitalopram dose for OCD

10-50 mg daily (exceeds Health Canada Guidelines)

8

Typical venlafaxine dose for OCD

225-375 mg daily; even up to 450 mg can be used

9

First line medication for OCD

SSRIs

10

Second line medications for OCD

Venlafaxine, clomipramine

11

Adjunct treatment for OCD

Risperidone, olanzapine, aripiprazole, quetiapine, haloperidol (only for poor insight, tics, schizotypal personality)

12

2nd line adjuncts for OCD

topiramate, memantine, riluzole

13

What if there is incomplete improvement after a medication trial?

Consider CBT.