Pharmacology Flashcards
(25 cards)
Name some Dihydropyridines
Nifedipine
Amlodipine
What do dihydropyridines do
Affect vascular smooth muscle
Name some phenylalklyamines
Verapimil
What do phenylalkylamines do?
Negatively chronotrophic and ionotrophic
What are 3 types of CCBs
Dihydropyridines
Phenylalklyamines
Benzothiazepines
Name some benzothiazepines
Diltiazem
What does diltiazem do?
Heart and peripheral vascular effects
What are side effects of vascular acting CCBs
Flushing Headache Oedema Palpitations Nifedipine causes reflex tachy and headaches
What are side effects of central acting CCBs?
Brady (reduced CO) AV block Can worsen heart failure Not used with BBs Constipation
Name some B1 selective BBs
Bisoprolol
Misoprolol
What do B1 BBs do?
Cardioselective
Name some non selective BBs
Propanolol
Atenolol
What are side effects of BBs?
Fatigue
Headache
Brady
Raynauds and claudication worsened
Name a thiazide diuretic
Bendroflumethiazide
Name 2 loop diuretics
Furosemide
Bumetanide
Name 2 K sparing diuretics
Spironolactone
Amiloride
What are side effects of loop diuretics?
Hypovolaemia
Hypotension
What are side effects of Thiazide diuretics
Gout
Erectile dysfunction
What are side effects of all diuretics?
Hyponatremia
Hypokalaemia
HYpomagnesia
Hypocalcaemia
Name a nitrate
Isosorbide mononitrate
How do Nitrates work?
Vasodilate arteries and veins reducing preload and afterload lowering BP`
When are thiazides contraindicated?
Gout
Hypercalcaemia
When are BBs contraindicated?
Asthma
Unstable heart failure
Heart block
Verapimil
When are ACEi contraindicated?
Renal artery stenosis
NSAIDs
K sparing diuretics
Pregnancy
