Pharmacology Flashcards Preview

Unit 5 > Pharmacology > Flashcards

Flashcards in Pharmacology Deck (26)
Loading flashcards...
1
Q

Agonists

A

Epi, NE, Clonadine

2
Q

Epi action

A

A1: constrict
B1: Iono, chrono, dromo
B2: dilate

3
Q

Epi Therapy

A

Broncospasm and vasoconstriction with local anesthetic

4
Q

Epi pharmacokinetics

A

rapid
quickly degraded
IM or IV (faster)

5
Q

Epi adverse effects

A

CNS: fear, anxiety, tension, tremor, arrhythmia

Antagonist to Insulin

6
Q

NE action

A

A1: constricts -> inc Bp -> vagal response -> reflex bradycardia (M2)

7
Q

NE Therapy

A

shock

8
Q

NE Adverse Effects

A

Anxiety, fear, tremor, skin problem

9
Q

Clonadine Action

A

A2: decreases sympathetic outflow from CNS

10
Q

Clonadine Therapy

A

withdrawal

HBP

11
Q

Antagonists (sympatholytics, blockers)

A

Prazosin

propranolol

12
Q

Prazosin Action

A

A1: equilibrium antagonist

Decrease TPR w/o affecting CO

13
Q

Prazosin Therapy

A

HBP

benign prostatic hyperplasia

14
Q

Prazosin Adverse Effects

A

1st dose: orthostat hypotension
sexual dysfunction
antihypertension side effects with sildenafil or nitrates

15
Q

Propranolol Action

A

B1: blocker (SA & AV)
decreases CO
bradycardia
Decreases TPR with prolong use

16
Q

Propranolol Therapy

A

HBP

17
Q

Propranolol Adverse Effects

A

Broncoconstriction

CNS depression, dizziness, fatigue, short term memory loss

18
Q

Anticoagulant

A

Rivaroxaban (xarelto)

19
Q

Rivaroxaban action

A

Factor Xa inhibitor

20
Q

Rivaroxaban Therapy

A

prevents DVT folllowing hip or knee surgery

21
Q

Rivaroxaban Adverse Effects

A

Bleeding

anesthesia or spinal puncture

22
Q

Rivaroxaban Anitdote

A

recombinant Factor Xa reverses life threatening bleeding

23
Q

Antiplatelet

A

Abciximab

24
Q

Abciximab (ReoPro) Action

A

Ab binds to glycoprotein to stop cross linking that form fibrin mesh and prevents platelet aggregation

25
Q

Abciximab Therapy

A

Acute coronary syndrome

26
Q

Abciximab Adverse Effects

A

Bleeding