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ACP CPG Review > Pharmacology - Adult Dosing > Flashcards

Pharmacology - Adult Dosing Flashcards

(48 cards)

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1
Q

Acetaminophen

A

-500-1,000 mg PO (specifically, 15 mg/kg to a maximum of 1,000 mg)
-24-hour maximum: 3 g (3,000 mg)

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2
Q

Acetylsalicylic Acid

A

-162 mg PO chewed and swallowed

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3
Q

Adenosine

A

-Initial dose: 6 mg IV rapid push
-Follow-up dose: 12 mg IV rapid push

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4
Q

Amiodarone (Ventricular fibrillation or Pulseless ventricular tachycardia)

A

-300 mg IV push; may repeat 150 mg IV after 10 minutes if VF/pVT persist

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5
Q

Amiodarone (Unstable ventricular tachycardia or Recurrent ventricular tachycardia following cardioversion)

A

-150 mg IV over 10 minutes

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6
Q

Atropine (Restoration of heart rate in bradydysrhythmias, Sinus bradycardia (rate < 50/minute) with hemodynamic compromise, Bradycardia secondary to atrioventricular nodal blocks)

A

-0.6 mg IV push to maximum dose of 0.04 mg/kg (~3 mg in most patients)

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7
Q

Atropine (Treatment of organophosphate poisoning)

A

-1-2 mg IM/IV; repeat every 5-60 minutes until symptoms resolve

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8
Q

Atropine (Control of secretions in palliative care)

A

-0.6 mg IM

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9
Q

Calcium Chloride

A

-1-2 g IV over 10 minutes
-May repeat once in 10 minutes if indications are still present

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10
Q

Clopidogrel

A

-For patients less than 75 years of age: 300 mg PO
-For patients over 75 years of age: 75 mg PO

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11
Q

Dexamethasone

A

-All indications: 8 mg IV/IO/IM/PO. PO preferred

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12
Q

Dextrose/D10W

A

-10-25 g IV (equivalent to 100-250 mL of D10W solution)

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13
Q

DimenhyDRINATE

A

-25-50 mg IV/IM
-12.5 mg IV/IM in elderly or frail patients
-May repeat dose once after 4-6 hours if required
-Give IM dose as direct injection; IV dose should be diluted with saline; administer medication at rate of 25 mg/min

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14
Q

DiphenhydrAMINE

A

-50 mg IM/IV or 1 mg/kg to maximum of 50 mg

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15
Q

Enoxaparin

A

-Immediately prior to administration of tenecteplase: 30 mg IV bolus
-Do not administer IV enoxaparin to patients > 75 years of age
-Following administration of tenecteplase: 1 mg/kg SC
For patients > 75 years of age: 0.75 mg/kg SC

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16
Q

EPINEPHrine (Anaphylaxis IM)

A

-0.5 mg IM every 5 minutes; may repeat up to 3 times

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17
Q

EPINEPHrine (Severe bronchospasm)

A

-0.5 mg IM every 5-20 minutes

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18
Q

EPINEPHrine (Pre-arrest anaphylaxis or bronchospasm

A

-50-100 mcg IV/IO; may repeat as necessary

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19
Q

EPINEPHrine (Cardiac Arrest)

A

-1 mg IV/IO every 3-5 minutes

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20
Q

EPINEPHrine (Peri-arrest hypotension)

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A

-10 mcg IV/IO slow push every 2-3 minutes as required

21
Q

EPINEPHrine (Significant bradycardia)

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A

-2-10 mcg/minute IV/IO infusion

22
Q

FentaNYL

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A

-Loading dose: 0.5-1.0 mcg/kg IM/IV/IO; maximum single dose 100 mcg; may repeat every 5 minutes to a total dose of 300 mcg
-Loading dose: 1.5-2.0 mcg/kg IN; maximum single dose 100 mcg; may repeat every 5 minutes to a total dose of 300 mcg
-Maintenance dose for long conveyances: 50 mcg IM/IV/IO every 10 minutes; maximum total dose of 250 mcg/hour
-Maintenance dose in long conveyances: 50-100 mcg IN every 10 minutes as required; maximum total dose of 250 mcg/hour.
-Consider reducing doses by half in patients > 65 years of age
-If pain is insufficiently relieved after a total of 1-3 mcg/kg, consider use of ketamine

23
Q

Glucagon

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A

-1 mg IM
-5 mg slow IV push for BB/CCB OD

24
Q

Hydrocortisone

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A

-100 mg bolus. IV preferred; IM acceptable if IV access is unobtainable or otherwise delayed. For IM administration, a large muscle (e.g., vastus lateralis) is preferred. Administration in the deltoid may cause subcutaneous atrophy.

25
Ibuprofen
-300-400 mg PO; may repeat every 4-6 hours; maximum daily dose 1,200 mg/day
26
Ipratropium
-500 mcg via nebulizer -160 mcg via metered-dose inhaler (8 x 20 mcg sprays) MDI and spacer use is strongly recommended for patients with signs of influenza-like illness, or other infectious respiratory conditions
27
KetAMINE (Analgesia)
-Intravenous/Intraosseous 0.3 mg/kg slow push May repeat 0.15 mg/kg after 5 minutes Maximum cumulative dose 0.6 mg/kg in 45 minutes -Intramuscular 0.5 mg/kg May repeat 0.3 mg/kg after 45 minutes
28
KetAMINE (Procedural Sedation)
-Intravenous/Intraosseous 0.1-0.5 mg/kg slow push every 60 seconds to effect -Consider starting at 0.5 mg/kg; use subsequent doses of 0.25 mg/kg or less as needed -Titrate to effect
29
KetAMINE (Anesthesia Induction and maintenance)
-Intravenous/Intraosseous: 2 mg/kg if shock index < 1 -Intravenous/Intraosseous: 1 mg/kg if shock index ≥ 1 -Half of required induction dose every 10-15 minutes as required
30
KetAMINE (Excited Delirium)
-Intramuscular 4-5 mg/kg bolus -Maximum single/cumulative dose 500 mg CliniCall consultation required if appropriate sedation is not achieved -Maximum volume of administration -Deltoid: 2 mL -Lateral thigh: 4-5 mL -Gluteal: 5 mL
31
Lidocaine (Ventricular Rhythm Control)
-1.0-1.5 mg/kg IV bolus -May repeat at 0.5-1.0 mg/kg; total maximum dose 3 mg/kg
32
Lidocaine (Local anesthesia during intraosseous cannulation (in conscious patients))
-Administer lidocaine, 40 mg Instill the lidocaine slowly, over 120 seconds, making sure to flush the appropriate amount of lidocaine through the extension; allow it to dwell in the bone marrow cavity for 60 seconds -Slowly flush the IO catheter with 5-10 mL normal saline following the administration of lidocaine
33
Lidocaine (Local anesthesia for awake intubation)
-There is no consensus on a maximum permissible dose; avoid exceeding 5 mg/kg topically where possible
34
Magnesium Sulfate (Control of ventricular arrhythmias (including Torsades de Pointes))
-For perfusing rhythms: 2 g IV over 15 minutes -In cardiac arrest: 4 g IV push
35
Magnesium Sulfate (Bronchospasm refractory to bronchodilation)
-2 g IV over 20 minutes
36
Magnesium Sulfate (Management of seizures in pregnancy associated with hypertension)
-Cardiac monitoring is required with magnesium administration -Administer the initial dose of 4-6 g intravenously over 20 minutes as a loading dose followed by 1-2 g per hour; otherwise, 5 g can be given intramuscularly (use bilateral buttocks) followed by 5 g IM every four hours -If seizures persist following the loading dose of magnesium, up to 4 g IV can be given over five minutes
37
Methoxyflurane (Penthrox)
-Self-administered relief from moderate to severe pain in conscious, hemodynamically stable patients -3 mL self-administered via inhaler; may repeat after 20 minutes; maximum total volume 6 mL Patients must self-administer as needed under direct EMR or paramedic supervision
38
MIDAZOLam
-2-5 mg IV/IO in increments to effect -5-10 mg IM -May repeat as required in small increments -Maximum dose from all sources is 30 mg
39
MORPHine
-CliniCall (or palliative care team) consultation required prior to selecting a dosing strategy. -0.1 mg/kg SC OR 2.5-5 mg SC -May repeat every 10-30 minutes as required based on blood pressure (> 100 mmHg) or as per CliniCall/palliative care team plan
40
Naloxone
-First dose:0.4 mg IM/IV -Second dose: 0.4 mg IM/IV if required -Third dose: 0.8 mg IM/IV if required -Fourth dose: 2 mg IM/IV if required (IV preferred) -4 mg IV -CliniCall consultation required prior to administration of further doses -10 mg IV
41
Nitroglycerin
-0.4 mg SL every 3-5 minutes
42
Ondansetron
-4 mg PO as a single dose Do not repeat dose
43
PhenyLEPHRine
-100 mcg IV slow push every 2-5 minutes to maximum of 500 mcg -Administer dose over 20-30 seconds
44
Salbutamol (Bronchospasm)
-5 mg nebulized; repeat doses back to back as necessary -4 x 100 mcg via metered dose inhaler with spacer; repeat as required
45
Salbutamol (Adjunctive management of hyperkalemia)
-10-20 mg via nebulizer; may require multiple doses back-to-back to reach total dose -4 x 100 mcg via metered dose inhaler with spacer; repeat as required
46
Sodium Bicarbonate
-1 mEq/kg IV/IO slow push May repeat 0.5 mEq/kg IV/IO slow push every 10-15 minutes as required -Tricyclic overdoses may require doses as high as 2-3 mEq/kg IV/IO
47
Tenecteplase
-0.5mg/kg IV (follow table)
48
Tranexamic Acid
-2 g IV push over 1 minute

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