Pharmacology - Antianginals Flashcards Preview

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Flashcards in Pharmacology - Antianginals Deck (6)
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1
Q

Nitrates are prodrugs of:

A

Nitric oxide

2
Q

MOA: Nitrates

A

vasodilators –> decrease preload;

decrease oxygen requirements

3
Q

Use: Nitrates

A

Can decrease infarct size and post-MI mortality;

For acute angina

4
Q

Class: Isosorbide

A

Nitrate

**for chronic use

5
Q

Class: Nitroglycerin

A

Nitrate

**for acute use

6
Q

Nitrates are 100% contraindicated with use of what drug?

A

Sildenafil (PDE-5 inhibitor) for ED;

cause a massive drop in BP