Pharmacology - Chapter 74 - Drugs for Asthma Flashcards Preview

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Flashcards in Pharmacology - Chapter 74 - Drugs for Asthma Deck (15)
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1
Q

What is Asthma?

A

Common chronic inflammatory disorder of the airway that occurs in children and adults.

2
Q

What are some signs of Asthma?

A

Breathlessness, tightness in the chest, wheezing, dyspnea (difficulty breathing), and cough.

3
Q

What causes Asthma?

A

50% of the patients have asthma due to allergens, and the rest due to airway inflammation from an unknown origin.

4
Q

What are the two classes of drugs for treating asthma?

A

Anti-inflammatory agents and Brochodilators.

5
Q

What are some anti-inflammatory agents used to treat Asthma?

A

Glucocorticoids (either inhaled or oral), Cromolyn (Intal) and Nedocromil (Tilade), and Leujotrine Modifiers (Singulair.)

6
Q

What are some Bronchodilators used to treat Asthma?

A

Beta-2 adrenergic agonists (inhaled) and (oral), Methylzanthines (Theophyline), and Anticholinergics (Ipratompium.)

7
Q

What are some advantages of inhalation drug therapy?

A

Therapeutic effects are enhanced, systemic effects are minimized, and relief of acute attack is rapid.

8
Q

What are the three types of inhalation drugs?

A

Metered-dose inhalers (MDI’s), Dry powder inhalers (DPI’s), and Nebulizers.

9
Q

Metered Dose Inhalers - they give a metered dose without releasing carbonfluorocarbon in the atmosphere - T/F?

A

False - they release CFC’s and cause the greenhouse effect!

10
Q

DPI’s - cause no risk to the environment. T/F?

A

True!

11
Q

Nebulizers - convert drug into a ___.

A

Mist.

12
Q

Nebulizers - less effective than an inhaler. T/F?

A

False! They are more effective!

13
Q

What are some adverse effects of inhaled glucocorticoids?

A

Oropharyngeal cadidiasis (infection), dysphonia (hoarseness), etc.

14
Q

It’s important to gargle after using inhaled glucocorticoids - T/F?

A

True!

15
Q

What are the two classes of Brochodilators (beta 2 adrenergic agonists)

A

Short Acting and Long Acting.

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