Pharmacology Final Study Guide Flashcards

(67 cards)

1
Q

Questions for pharm final: unanswered

A

What to do with red and syndrome occurs
Metronazole adverse effects
Black box warning for quinolone
What do we use to treat UTIs
How to know an antibiotic is working
Practice infusion rates
What laxative is safe for long term use (bulk)
Adverse effects for PPIs
Contraindications for cyclobenzaprine
Know fastest way to get medication to a patient
Know how a PCA works
Antidote for opioids
A lot of delegation
What to do when a patient is having an allergic reaction
Cultural considerations for pain (how different cultures deal with pain)
Adverse effects of opioids.
Contraindications for acetaminophen
Medications for hypothyroidism
Betablocker nursing considerations.. what to do before you give a beta blocker
Contraindications for beta blockers
Steroid patient education (what are you gonna teach someone on corticosteroids
Adverse effects on cimetidine
Know action of albuterol
How to give a sub-q heparin shot, what to give, and how to monitor
What to give when the dose is too high. (If you gave the wrong med)
Know ethical principles
Herbal supplements that interact with warfarin
Know valerian
What to monitor for when someone is taking a thiazide
Know what poly pharmacy is
What to report for lisinopril
Dietary considerations for statin drug
Weight based calculation
Antidote for heparin
Antidote for warfarin (vitamin k)
Digoxin toxicity symptoms
What to monitor with furosemide

2 Weight math
1 Infusion rate but not drip
Other 5 questions are basic med math

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2
Q

How to take extended release tablets

A

Examples are SR (slow release or sustained release)
SA (sustained action)
CR (controlled release)
XL (extended length)
XT (extended time)
Oral dosages must not be crushed as this could cause accelerated release of drug from the dosage form and possible toxicity
Enteric coated tables also are not recommended for crushing as it would cause disruption of the tablet coating designed to protect the stomach lining from the local effects of the drug and/or protect the drug from being disrupted by stomach acid.

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3
Q

What are normal potassium levels

A

3.5 to 5.2 mEq/L

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4
Q

What are indications for antibiotics

A

Empiric therapy: we don’t know bacteria yet
Definitive therapy: we know the specific bacteria
Prophylactic therapy: give to someone getting abdominal surgery/trauma for infection

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5
Q

Sulfonamides indication

A

Urinary tract infection

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6
Q

Macrolides Indications

A

Treat infections typically treated with penicillin (PCN) in clients with PCN allergy

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7
Q

Quinolones indications

A

Upper respiratory, gastrointestinal, urinary tract, bone, and joint infections

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8
Q

Aminoglycoside examples

A

Gentamicin
Tobramycin
Neomycin
Amikacin

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9
Q

Losartan indication

A

Beneficial in patients with hypertension and heart failure and stroke prevention
These medications block the action of angiotensin 2 in the body resulting in vasodilation (arteriales and veins) and excretion of sodium and water.

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10
Q

Contraindications for phenobarbital

A

Drug under the class of barbiturates. Indication is to slow down the activity of the brain to result in sedation, anesthesia, and control seizure.

Contraindications
Respiratory, kidney, or liver disease
Caution in older adults (higher risk for falls & accumulate more in older adults)

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11
Q

Theophylline and dietary restrictions

A

Theophylline is under Xanthine derivatives
Indication: bronchoconstriction. Has bronchodilating properties NOT for the management of acute asthma attack
Treat asthma and COPD

Dietary Restrictions
Caffeine increases CNS and cardicac adverse effects & increase theophylline levels
Avoid any caffeinated beverages with medication
(Examples: coffee, chocolate, tea, coke)

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12
Q

Signs of hyperthyroidism

A

Nervousness, irritability, tremors, insomnia
Tachycardia, palpitations
Increased appetite, weight loss, diarrhea
Muscle weakness, fatigue
Heat intolerance, flushing

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13
Q

Adverse effects of aspirin

A

Prolonged bleeding time, thrombocytopenia (platelet count lower than 150,000 per/mm3)
Tinnitus, hearing loss (ASA)
N/V, dyspepsia (indigestion/ bloating)
GI bleed

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14
Q

Assessment for allergies

A

Ask everything that the patient is taking even herbs are apart of nursing assessment. Ask a broad question for the patient to answer

Most patients are allergic to morphine but itching is an anticipated reaction .. we worry if an airway closes up

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15
Q

Pharmacotherapeutics definition

A

Clinical use of drugs to prevent and treat diseases. Defines the principles of drug reactions.

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16
Q

Vancomycin indications

A

MRSA (methicillin resistant staphylococcus aureus infection) caused by a type of staph bacteria that’s become resistant to many of the antibiotics used to treat ordinary staph infections)
C. Diff infections

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17
Q

Action of Metoclopramide

A

One of the antiemetic medications that help prevent or relieve nausea and vomiting.
Helps to stimulate peristalsis to get food out quicker

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18
Q

Medications with a side effect of diarrhea

A

Magnesium (antacids)
Antibiotics (common adverse effects)
Montelukast & zafirlukast (leukotriene receptor antagonists for treatment and prevention of asthma)
Antiemetics

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19
Q

Nursing intervention taking calcium carbonate

A

Monitor bowel function
Administer stool softeners
Monitor for severe diarrhea
Monitor phosphorus (can contribute to kidney stones) and magnesium levels (magnesium reduces the risk of kidney stones)

Compliance can be due to the frequency of administration (most people dont want to take medication 7x a day). remind them that medication is for relief of pain and healing of ulcer

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20
Q

What is NPH peak

A

NPH is intermediate acting (cloudy insulin)
Peak time is 4-14 hours

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21
Q

What to do when interrupted while preparing a medication

A

(Not sure what the question is asking… assuming this means to toss any medication that isn’t labeled?? Also dont administer medicine another nurse has prepared)

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22
Q

What to do when someone asks for pain medication

A

Perform a thorough health history, nursing assessment an medication history.
Assess their pain level
- including intensity of pain, including onset, location and quality
- actual rating of the pain using a pain assessment scale
- assess pain before, during, and after the pain intervention

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23
Q

Teaching Diphenoxylate/ atropine

A

Treatment for diarrhea

If experiencing diarrhea, drink small amounts of clear liquids or a commercial oral electrolyte solution to maintain electrolyte balance for the first 24 hr.
Avoid drinking plain water to replace fluids because it does not contain necessary electrolytes that has been lost in stool
Avoid caffeine. Caffeine exacerbates diarrhea by increasing GI motility

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24
Q

Medication to remove mucus

A

Guaifenesin (an expectorant)
-helps to loosen or thin the sputum
-reduce the viscosity of secretions
-disintegrate and thin secretions

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25
What negligence looks like
The failure to act in a reasonable and prudent manner or failure of the nurse to give the care that a reasonable cautious nurse would render or use under similar circumstances
26
Normal glucose levels
Between 70 mg/dL and 100 mg/dL
27
Side effects of nasal decongestants
Examples of nasal decongestants: pseudoephedrine (oral), phenylephrine (topical), beclomethasone, fluticasone (intranasal steroids) **Side effects** Nervousness, tremors Palpitations, hypertension Headache, dizziness Local mucosa dryness and irritation Insomnia (Oral and nasal together can cause drug toxicity)
28
complications of long term use of laxatives
Fluid and electrolyte imbalance Hypokalemia: as potassium concentration is high in stool water. - Hypokalemia can cause muscle weakness.
29
Ondansetron adverse effects
Headache, dizziness Dysrhythmia Diarrhea
30
What to do with Redman syndrome
Infusion related to vancomycin Red man syndrome occurs if medication is infused too quickly (causing pruritus, hypotension and tachycardia) Vancomycin infusion should be discontinued immediately ( a dose of diphenhydramine [an antihistamine aka Benadryl] can abort reaction) .
31
Adverse effect of metronidazole
Miscellaneous antibiotic Adverse effects *Nausea, dry mouth, headache *Metallic taste
32
Quinolone Black box warning
Blackbox warning are required for all quinolones because of the increased risk for tendinitis and tendon rupture - As well as peripheral neuropathy central system effects (seizures), and exacerbation of myasthenia gravis. - Tendon rupture is more common in older adults, patients with renal failure, and those receiving glucocorticoid therapy
33
What do we use to treat UTIs
Sulfonamides indication is to treat urinary tract infection Fluoroquinolones are also indicated for UTIs
34
How to know if an antibiotic is working
**Reduction of manifestations (fever, pain, inflammation, and adventitious breath sounds) Resolution of infection** Antibiotics usually start working right away but take several days to notice an effect. It is important that patients complete their full course of antibiotics as prescribed, even when their symptoms have improved, to prevent relapse of infection and the development of antibiotic resistance
35
What laxative is safe for long term
Bulk forming : psyllium and methylcellulose
36
PPIs adverse effects
Pneumonia Osteoporosis C. Diff- associated diarrhea Wrist, spine, hip fracture Hypomagnesemia
37
Contrainidications for cyclobenzaprine
Cyclobenzaprine: muscle relaxant, can treat pain and stiffness caused by muscle spasms **Contraindications** Liver and renal function - obtain baseline liver function and perform periodic follow-up liver function tests *hyperthyroidism *myocardial infarction *heart failure/ heart block **adverse effects** Eurphoria Lightheadedness, dizziness, drowsiness Muscle weakness Fatigue
38
Fastest way to get medication to a patient
Intravenously (IV)
39
Abbreviations
*AC* - Before meals *PC* - After meals *Daily* - Everyday, daily *bid* - Twice a day *tid* - Three times a day *qid* - Four times a day *qh* - every hour *At bedtime* - At bedtime *qn* - Every night *stat* - immediately *Ever other day* - every other day *prn* - as needed *3 times weekly* - three times per week *biw* - twice per week
40
Know how a PCA works
PCA is a patient controlled analgesia - a needle attached to an IV (intravenous) line is placed into one of your veins. A computerized pump attached to the IV lets you release pain medicine by pressing a handheld button.
41
Antidote for opioids
Naloxone Other medications: - Naltrexone -Methylnaltrexone -Alvimopan These medications work on morphine, fentanyl, methadone, codeine, oxy….
42
Delegation
The registered nurse cannot delegate responsibilities related to making nursing judgments. An examples would be: Anew admission who is highly unstable should be assigned to a registered nurse; the care of a stable chronically ill patient who is relatively stable and more predictable than a serious ill and unstable acute client can be delegated to the licensed practical nurse.
43
What to do when a patient is having an allergic reaction
First assess make sure they can breath Stop administering the medication and notify the providers
44
Cultural considerations for pain
African American : believe in the power of healers who rely strongly on the religious faith of people, and often use prayer in the laying of hands for a relief of pain Hispanic Americans: believe in prayer, the wearing of amulets, and the use of herbs and spices to maintain health and wealth specific herbs are used in teas and therapies often including religious practices, massage and cleanings Chinese : include acupuncture, herbal remedies, Yin and yang balancing, and cold treatment Asian and Pacific Islander’s : often reluctant to express their pain because they believe that the pain isn’t Godswill or punishment for past sins Native Americans: treatments for pain include massage, the application of heat, sweat baths, herbal remedies, and being in harmony with nature Arab culture : are expected to express their pain openly and anticipate immediate relief, preferably through injections or intravenous drugs
45
Adverse effects of opioids
Respiratory depression Constipation Orthostatic hypotension Urinary retention Cough suppression Sedation biliary colic Nausea, vomiting Opioid toxicity triad ( coma, respiratory depression, and pinpoint pupils)
46
Contraindications for acetaminophen
Bone marrow suppression - monitor CBC, including platelets Gastrointestinal (GI) distress - monitor for bleeding (coffee-ground emesis; bloody stools) MI or stroke - Monitor for cardiac status especially in clients with history of cardiac disease
47
Medications for hypothyroidism
High TSH Low TH Medication: Levothyroxine
48
Beta blocker nursing considerations/ what to do before you give a beta blocker
Monitor pulse: if below 50/min hold medication and notify provider Metoprolol, propranolol: in clients who have diabetes mellitus monitor blood hypoglycemia which can mask tachycardia. Nursing administration: -Administer medications orally, usually once or twice a day -take with food to increase absorption
49
Contraindication for beta blockers
Clients who have AV block and sinus bradycardia Asthma, bronchospasm (non cardio selective drugs such as propranolol) Metoprolol and atenolol are better since they are cardioselective (alpha 1) In general, use beta-adrenergic blockers cautiously in clients who have myasthenia gravis, hypotension, peripheral vascular disease, diabetes mellitus, depression, and in older adults with history of allergies
50
Steroid patient education
**Glucocorticoids: dexamethasone** - Client education: * eat potassium rich foods ( because of fluid and electrolyte disturbances) *risk of osteoporosis can be reduced by giving calcium supplements and vitamin D. * clients should not receive immunizations while on glucocorticoid therapy because they decrease antibody response to vaccines. *PUD- educate client to take the medication with meals .. and report black tarry stools **Glucocorticoids: beclomethasone** -Client education * inhalation drug. Rinse mouth or gargle with water after use, monitor for redness, sores, or white patches Baseline vital signs : respiratory rate 12-24 breath/min **Glucocorticoids: prednisone** -client education * Perform weight bearing exercises * consume a diet with sufficient calcium and vitamin D intake * Report indications of muscle weakness * Avoid NSAIDs, report for black, tarry stools *( notify if early manifestation of infection, and avoid large crowds if possible
51
Adverse effect of cimetidine
Cimetidine: H2RBs: treatment of acid related disorders, adjunct therapy to control, management of urticaria Adverse effects Confusion, disorientation in the elderly Impotence Gynecomastia
52
Action of albuterol
Beta 2 adrenergic agonist Short acting : good for an acute attack. Something that’s sudden Action: Act by selectively activating the beta 2 receptors in the bronchial smooth muscle, resulting in bronchodilator. As a result: - Bronchospasm is relieved -Histamine release is inhibited -ciliary motility is increased
53
How to give Sub- Q heparin shot, what to give and how to monitor. H
Enoxaparin - subQ injectable only — Bridge therapy — do not expel air bubble Monitor bleeding time - Normal activated partial thrombophlebitis time (aPTT): 30-40 sec (60-80 sec during treatment) <— is the goal Remember contraindications: bleeding, thrombocytopenia (normal 150,000 -400, 000) , and pregnancy
54
What to give when the dose is too high (if you gave the wrong medication)
55
Know ethical principles
Autonomy: Beneficence: Nonmaleficence: Veracity: telling the truth Justice: equality Confidentiality:
56
Herbal supplements that interact with warfarin
Ginkgo Bilbao, ginger, spinach, St. John’s Wort, cranberry, green tea, chamomile tea
57
Know valerian
Valerian root, consisting of fresh underground plant parts Common uses: relief of anxiety, restlessness, sleep disorders Adverse effects: Central nervous system depression, hepatotoxicity, nausea, vomiting, anorexia, headache, restlessness, insomnia Contraindicated in patients with cardiac disease, liver disease, or those operating heavy machinery including treatment of insomnia, moderate sedation
58
What to monitor for when someone is taking a thiazide
Hyponatremia *Monitor electrolytes and weight Hypokalemia and hypochloremia *Monitor cardiac status and K+ levels especially if taking digoxin Hyperglycemia *Monitor for an increase in blood glucose levels Hyperuricemia *Monitor uric acid, magnesium, hdl and ldl and triglyceride levels
59
What is poly pharmacy
The use of many different drugs concurrently in treating a patient, who often has several health problems. * As the number of medications a person takes increases, so does the risk for drug interaction and ADRs. *Recognizing poly pharmacy is important to reduce the incidence of adverse outcomes
60
What to report for lisinopril
Lisinopril is an ACE inhibitor: the drug of choice for hypertensive clients with heart failure Important to report angioedema Adverse effects also include: -Orthostatic hypotension -cough -neutropenia -rash -dysgeusia (metallic taste in mouth) -hyperkalemia
61
Dietary considerations for statin drugs
Statin drugs: Antilipemic agents for high cholesterol (hypercholesteremia) Examples : Atorvastatin, simvastatin ** Drug food interaction** — increased levels of statin with grapefruit juice (can lead to rhabdomyolysis —> damage heart & kidneys)
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Weight based calculation
63
Antidote for heparin
Protamine sulfate
64
Antidote for Warfarin
Vitamin K
65
Digoxin toxicity symptoms
Digoxin : Cardiac Glycoside Action is: positive inotropic (increase force of contraction), negative chronotropic (reduce heart rate), and negative dromotropic effects (reduce conductivity of heart) **Toxicity symptoms** Colored vision, halo vision, flickering lights (Vincent van gough example) Anorexia, nausea, vomiting, diarrhea
66
What to monitor with furosemide
Furosemide (example of a loop diuretic) -Indication is first line anti hypertensive drug, pulmonary edema caused by heart failure **Monitor** Electrolytes (assess dry mouth, increased thirst, minimal urine output, and weight loss) Urine output (less than 30 mL/hr stop medication) Blood pressure since can cause hypotension Monitor cardiac status and potassium levels Monitor blood glucose, uric acid, calcium, magnesium and lipid levels
67
Nursing process
*Assessment* — Data collection, review, and analysis — subjective info is what the patient verbalizes — objective data is laboratory results *Human Needs Statement* — statement of client’s response to the illness *Planning* — goals — outcome criteria *Implementation* — Nursing actions — client education *Evaluation* — determining the status of the goals and outcomes of care