Pharmacology for delirium/dementia Flashcards
(25 cards)
olanzapine (Zyprexa) action
Delirium
olanzapine (Zyprexa) onset, peak, duration for PO
O: unknown
P: 6h
D: unknown
olanzapine (Zyprexa) onset, peak, and duration for IM
O: rapid
P: 15-45 m
D: 2-4 h
haloperidol (Haldol) action
Delirium
haloperidol (Haldol) onset, peak, and duration for PO
O: 2 h
P: 2-6 h
D: 8-12 h
haloperidol (Haldol) onset, peak, and duration for IM
O: 20-30m
P: 30-45 m
D: 4-8 h
haloperidol (Haldol) onset, peak, and duration for IV/dose
All: unlabeled use
Give 0.5 mg - 5 mg every 30 m for acute psychosis/delirium.
Typical dosing for olanzapine
5-10 mg/day - 20 mg/day
Side effects for olanzapine
orthostatic hypotension, dry mouth, sedation, weakness, insomnia, tardive dyskinesia
Side effects for Haldol
dry mouth, orthostatic hypotension, constipation, dizziness. Long time use may result in tardive dyskinesia
donepezil (Aricept) action
Dementia
donepezil (Aricept) onset, peak, and duration for PO
O: Unknown
P: several weeks
D: 6 weeks
donepezil (Aricept) dosing
5 mg-10 mg a day (after 4-6 weeks)
Side effects of donepezil (Aricept)
insomnia, headache, fatigue, dreaming, dizziness, GI upset
memantine (Namenda) action
dementia
memantine onset, peak, and duration for PO
O: unknown
P: 3-7 hours
D: 12 hours
memantine (Namenda) dosing
5 mg once daily - 10 mg daily
side effects of Namenda
dizziness, headache, constipation
lorezapam (Ativan) action
anxiety related to dementia
lorezapam (Ativan) onset, peak and duration for PO
O: 15-60m
P: 1-6 h
D: 8-12 h
lorezapam (Ativan) onset, peak and duration for IM
O: 30-60m
P: 1-2 h
D: 8-12 h
lorezapam (Ativan) onset, peak and duration for IV
O: 15-30 m
P: 15-20 m
D: 8-12 m
lorezapam (Ativan) can be given sublingual (T/F)
T. Has a rapid absorption
dosing for lorezapam (Ativan)
Always start with the lowest dose of 0.5 mg
