Pharmacology of Gonadal Hormones 5 Flashcards Preview

Repro/GU > Pharmacology of Gonadal Hormones 5 > Flashcards

Flashcards in Pharmacology of Gonadal Hormones 5 Deck (3)
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1
Q

What are the common androgen receptor antagonists?

A
  • Flutamide
    • treat hirsutism in females
    • treat prostatic carcinoma and satyriasis in males
  • Spironolactone
    • aldosterone antagonist
    • can inhibit androgen receptors
2
Q

What are the common 5-alpha reductase (synthesis) inhibitors?

A
  • Finasteride (vs. type 2)
  • Dutasteride (vs. types 1 and 2)
  • Used to treat benign prostatic hypertrophy
3
Q

What is gossypol?

A
  • Cottonseed derivative
  • Damages seminiferous tubules and decreases sperm
  • Has been used as a male contraceptive for this “antigerminal” action

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