Pharmacology Principles

Question 1

Phase 1: Pharmaceutical

Answer 1

-All oral drugs must go through dissolution in order to be absorbed
-Dissolves in stomach

Question 2

Three Phases of Drug Action

Answer 2

1. Pharmaceutic Phase
2. Pharmacokinetic Phase
3. Pharmacodynamic Phase`

Question 3

Phase 2: Pharmacokinetic Phase

Answer 3

-Drug moving through the body and what the body does to the drug
-Absorption, Distribution, Metabolism, Excretion

Question 4

Phase 2: Absorption (Pharmacokinetic Phase)

Answer 4

Occurs in small intestines to be absorbed into blood

Question 5

Phase 2: Distribution (Pharmacokinetic Phase)

Answer 5

Drug leaving blood through cell membrane to the site of action (where its intended to exert effects)

Question 6

Phase 2: Metabolism/ Biotransformation (Pharmacokinetic Phase)

Answer 6

-Once drug has exerted its effects it is broken down by the liver
-Drug goes from lipid soluble metabolite to water soluble metabolite

Question 7

Phase 2: Excretion (Pharmacokinetic Phase)

Answer 7

Kidneys excrete the water soluble metabolite

Question 8

Which phase does IV drug skip?

Answer 8

Absorption

Question 9

Drugs must be _________ to pass through phospholipid membrane

Answer 9

lipid soluble

Question 10

__________ drugs require passage through channels or pores

Answer 10

Water soluble