Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

PHARMACOLOGY > PHARMACOLOGY- Toxicities and side effects > Flashcards

PHARMACOLOGY- Toxicities and side effects Flashcards

(79 cards)

Start Studying
1
Q

Which is the antidote for Acataminophen?

A

N- acetylcysteine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the effect of N- acetylcysteine in case of Acetaminophen intoxication?

A

Replenishes glutathione

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

This is the antidote in case of AChE inhibitors, organophospates

A

Atropine followed by pralidoxime

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Antidote for Amphetamine (basic) intoxication

A

NH4Cl (acidify urine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

For Antimuscarinic, anticholinergic agents this the antidote

A

Physostigmine salicylate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

In case of Antimuscarinic, anticholinergic agents what is the effect of physostigmine salicylate

A

Control hyperthermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Benzodiazepines intoxication can be treated with…

A

Flumazenil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Glucagon is the antidode for this intoxication….

A

β blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

For Carbon monoxide intoxication which is the treatment?

A

100% O2, hyperbaric O2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

For Cooper, arsenic, gold intoxication which is the antidote?

A

Penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

In case of Cianide intoxication, what is the treatment?

A

Nitrite+ thiosulfate, hydroxocobalamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Anti dig Fab fragments is the antidote for this intoxication

A

Digitalis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

For Heparin intoxication which is the antidote?

A

Protamine sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Name the alternatives of treatment for iron intoxication

A

Deferoxamine, deferasirox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In case of Lead intoxication this are the possible treatments

A

EDTA, dimercaprol, succimer, penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

For Mercury, arsenic and gold intoxication which is the antidote?

A

Dimercaprol (BAL), succimer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

In case of Methanol, ethylene glycol, what is the antidote?

A

Fomepizole> ethanol, dialysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Where do we find Ethylene glycol?

A

Antifreeze

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

In methemoglobin intoxication these are the alternatives of antidote

A

Methylene blue, vitamin C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which is the antidote for Opiods?

A

Naloxone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

NaHCO3 (alkalinize urine), dyalisis help in case of intoxication by…

A

Salicylates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Tricyclic antidepressant overdose can be treated with…

A

NaHCO3 (plasma alkalinization)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Aminocaproic acid is this antidote for these situations…

A

tPA, streptokinase, urokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

In case of Warfarin intoxication what is the antidote

A

Vitamin K, plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
When is recommended the ise of plasma in Warfarin intoxication?
If activate bleeding
26
These drugs cause coronary vasospasm
Cocaine Sumatriptan Ergot alkaloids
27
Which medications can cause cutaneous flushing?
Vancomycin Adenosine Niacin Ca2+ channel blockers
28
Which drugs can cause dilated cardiomyopathy?
Doxorrubicin | Daunorubicin
29
Medications that can cause Torsades de pointes
Class III (eg. Sotalol), and class IA (eg quinidine), antiarrhytmics, macrolide, antipsycotics, Tricyclic antidepressant
30
Causal agents of Adrenocortical insufficiency
Hypothalamic–pituitary–adrenal axis suppression secondary to glucocorticoid withdrawl
31
Drugs that can cause hot flashes
Tamoxifen, clomiphene
32
Which medications can cause hyperglicemia
Tacrolimus, protease inhibitors, Niacin, HCTZ, β blockers, Corticosteroids
33
Drugs as causal agents of Hypothyroidism
Lithium, amiodarone, sulfonamides
34
This antibiotic can cause Acute cholestatic hepatits, jaundice
Erythromycin
35
Drugs that commonly cause Diarrhea
Metformin, Erythromycin, Cholchicine, Orlistat, Acarbose
36
Which drugs might cause focal to massive heptatic necrosis?
Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acethaminophen
37
This medicine can cause Hepatitis
Isoniazid
38
Drugs as causal effect of Pancreatitis
Didanosine, Cortitosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (furosemide, HCTZ)
39
Medications related to Pseudomembranous colitis
Clindamycin, ampicillin, cephalosporins
40
Who predispose to superinfection by resistant C. Difficile
Antibiotics
41
Name drugs that might cause Agranulocytosis
Dapsone, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthiouracil
42
Drugs that possible cause Aplastic anemia
Carbamazepine, Methimzole, NSAIDs, Benzene, Chloramphenicol, Propythiouracil
43
Drugs related to Direct Coombs-positive hemolytic anemia
Methyldopa, penicillin
44
Causes gray baby syndrome
Chloramphenicol
45
Using these drugs can cause Hemolysis in G6PD deficiency
Isoniazide, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin
46
Which drugs can cause Megaloblastic anemia?
Phenytoin, Methotrexate, Sulfa drugs
47
Drugs related to Thrombocytopenia
Heparin, cimetidine
48
This drugs increase the risk for Thrombotic complication
OCPs (egs estrogens)
49
Drugs that cause fat redistribution
Protease inhibitors | Glucocorticoids
50
These medications cause Gingival hyperplasia
Phenytoin, Verapamil, cyclosporin, nifedipine
51
Drugs that might cause Hyperuricemia (gout)
Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine
52
Durgs related to Myopathy
Fibrates, niacin, colchicine, hydroxychloroquine, interferon α
53
These drugs are associated to Osteoporosis
Corticosteroids, heparin
54
Which medications might cause Photosensitiviy?
Sulfonamides, Amiodarone, Tetracyclines, 5 FU
55
These drugs are related to Rash (Stevens Johnoson syndrome)
Anti-epileptic drugs (ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital) Allopurinol Sulfa drugs Penicillin
56
Drugs as causal agents of SLE like syndrome
Sulfa drugs, Hydralazine, Isoniazide, Procainamide, Phenytoin, Etanercept
57
This antibiotic cam cause Teeth discoloration
Tetracyclines
58
Which musculoeskeletal and cartilage side effect can Fluoroquinolones can cause?
Tendonitis, Tendon rupture, and cartilage damage
59
Name drugs rekated to Cinchonism
Quinidine, quinine
60
These drugs might cause Parkinson like syndrome
Antipsychotics, Reserpine, Metoclopramide
61
Which drugs can cause seizures?
``` Isoniazid (vitamin B6 deficiency) Bupropion Imipenem/ cilastatin Tramadol Enflurance Metoclopramide ```
62
Drugs related to Tardive dyskinesia
Antipsycochotics, metoclopramide
63
These medications can cause Diabetes insipidus
Lithium, demeclocycline
64
Which is the risk of expired Tetracyclines?
Fanconi Syndrome
65
Name drugs that can cause Hemorrhagic cystitis
Cyclophosphamide, ifosfamide
66
How do you orevent Hemorrhagic cystitis caused by Cyclophosphamide and ifosfamide?
Prevent by coadministeringwith mesna
67
You need to be careful administering these drugs because they can cause Interstitial nephritis
Methicillin, NSAIDs, Furosemide
68
Which drugs are related to Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
Carbamazepine Cyclophosphamide SSRIs
69
This drug can cause dry cough
ACE inhibitors
70
Which drugs are related to Pulmonary fibrosis
Bleomycin Amiodarone Busulfan Methotrexate
71
Name drugs that can cause Antimuscarinic reaction
Atropine TCAs H1 blockers Antipsychotics
72
Drugs that cause Disulfiram like reaction
``` Metronidazole Certain cephalosporins Griseofulvin Porccarbazine First generation sulfonylureas ```
73
Which medications can cause Nephrotoxicity/ ototoxicity?
Aminoglycosudes Vancomycin Loop diuretics Cysplastin
74
These are Inducers of Cytochrome P450 interactions
``` Chronic Alcohol Modafinil St John's wort Phenytoin Phenobarbital Neviparine Rifampin Griseofulvin Carbamazepine ```
75
Name substrates of Cytochrome P450
``` Anti-epileptics Antidepressants Antipsychotics Anesthetics Theophylline Warfarin Statins OCPs ```
76
Cytochrome P450 inhibitors
``` Acute alcohol abuse Gemfibrozil Ciprofloxacin Isoniazid Grapefruit juice Quinidine Amiodarone Ketoconazole Macrolides Sulfonamides Cimetidine Ritonavir ```
77
Sulfa drugs
Probenecid, Furoseminde, Acetazolamide, Celecoxib, Thiazides, Sulfonamide antibiotics, Sulfasalazine, Sulfonylureas
78
Symptoms of Sulfa allergies
``` Fever Urinary tract infection Stevens Johnson syndrome Hemolytic anemia Thrombocytopenia Agranulocytosis Urticaria (hives) ```
79
Which are the repercussions of Sulfa allergies?
Symptoms range from mild to life threatening

PHARMACOLOGY (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions