Pharmacotherapeutics

Question 0

Adalimumab (Humira)

Answer 0

Treats plaque psoriasis and psoriatic arthritis

SQ

Question 1

Etanercept (Enbrel)

Answer 1

Treats plaque psoriasis and psoriatic arthritis

SQ

Question 2

Infliximab (Remicade)

Answer 2

Treat plaque psoriasis and psoriatic arthritis

IV

Question 3

Golimumab (Simponi)

Answer 3

arthritis only, not plaque psoriasis

SQ

Question 4

Ustekinumab (stelara)

Answer 4

Interfere with IL-12 and IL-23

SQ

Question 5

Mycophenolate Mofetil (CellCept)

Answer 5

used in combination with other therapies for moderate to severe
oral
category D

Question 6

Hydroxyurea

Answer 6

antimetabolite for hematologic malignancies
psoriasis only
for pt with liver dx who would be at risk of ADRs with other antipsoriatic agents, less effective
Oral

Question 7

pediatrics

Answer 7

0-18 years

Question 8

premature

Answer 8

<37 weeks gestation age

normal is 40 weeks

Question 9

neonate

Answer 9

1 day to 1 month

Question 10

infant

Answer 10

1 month to 1 year

Question 11

children

Answer 11

1-12 years

Question 12

adolescent

Answer 12

12 - 18 years

Question 13

chloramphenicol

Answer 13

gray baby syndrome

could not metabolize drug & accumulated in body & turned grey

Question 14

thalidomide

accutane

Answer 14

phocomelia

flipper like limb syndrome

Question 15

sulfonamides

Answer 15

kernicterus

displace bilirubin and accumulates = jaundice = cross BBB & lodge brain = permanent brain damage.

Question 16

tablets and capsules for children <6

Answer 16

cannot swallow so use liquids, oral disintegrating tables, cheweable tablets

Question 17

subcutaneous in neonates

Answer 17

unpredictable, more viable than intramuscular injections, absorption increased in neonates, should inject in abdomen = less risk of injecting into muscle/bone.

Question 18

intramuscular

Answer 18

not ideal in neonatal due to absorption issues

Question 19

IV bags for neonates

Answer 19

used for maintenance fluids only

Question 20

syringe pump

Answer 20

most common technique in pediatrics
allows med to be administered over a set time at specific rate
concentrated solution is slowly dripped into the maintenance fluid for dilute administration

Question 21

volumetric set

Answer 21

Buretrol or Metriset
allows for administration of a set volume of medication into a specific volume of diluent to create a patient specific concentration
allows for tubing to the flushed to ensure entire dose is given

Question 22

intraosseous infusion

Answer 22

when IV access cannot be gained
should not be used if pt is over 6 years old
can infuse most meds & fluids w exception of lipid based products

Question 23

pediatric chief complaint

Answer 23

presented same as in adults but states who is giving the information

Question 24

past medical history

Answer 24

adult chart + prenatal & birth history. | NVSD = normal spontaneous vaginal delivery

Question 25

pediatric social history/family history

Answer 25

child's primary living environment, daycare, genetic illnesses in family

Question 26

diet history

Answer 26

important for infants | document types of food & amts.

Question 27

pediatric heart rate

Answer 27

starts high prior to birth, dips slightly at birth, slowly decreases until age 14 when adult normals are reached

Question 28

pediatric respiratory rate

Answer 28

highest at birth, declines until normal adult at 15 years

Question 29

pediatric blood pressure

Answer 29

starts low and increases with age.

Question 30

pediatric serum creatinine

Answer 30

for the first 10 days of life, the value obtained is indicative of the mother's renal health, not the child's renal health levels are dependent on muscle mass and don't reach adult normals until adolescence

Question 31

pediatric creatinine clearance

Answer 31

maturation occurs btw 6 mo-3 years

Question 32

pediatric bilirubin

Answer 32

total bilirubin peaks at 3-7 days of life and decreases as the liver's ability to conjugate matures. conjugated bilirubin should remain the same throughout a health childhood since body will excrete any excess.

Question 33

pediatric fluids, electrolytes, nutrition (FEN) for non-dehydrated pediatrics patients

Answer 33

100 ml/kg for the first 10kg 50 ml/kg for the 2nd 10 kg 20 ml/kg for each extra kg over 20 kg 3 years = D5/.45 NaCl + 20 mEq KCl/L divide by 24 to get ml/hr rate

Question 34

nelson's textbook of pediatrics

Answer 34

widely available, general reference, req some medical terminology knowledge, a "dipro's for pediatrics"

Question 35

pediatric dosage handbook by lexicomp

Answer 35

excellent drug reference, nothing on diagnosis or treatment plans, FDA information

Question 36

Current Concepts in Pediatric Diagnosis and Therapy

Answer 36

UTD std of care, assume you know background on dx staet

Question 37

Harriet Lane Handbook

Answer 37

good section on dx & testing, some difficulties w drug section, designed for physicians, questionable drug reference

Question 38

Nelson's Essentials of Pediatrics

Answer 38

handbook on common pediatric dx states

Question 39

Teddy Bear Book

Answer 39

peds specific compatibility info of IV for each conc used in children, found very rarely in other resources

Question 40

Neofax

Answer 40

limited to medications in neonatal pop