pharmacy

Question 1

what is the EPMA ?

Answer 1

electronic prescribing and medicines administration

Question 2

what are some benefits of EPMA ?

Answer 2

solves most prescribing issues
efficiency - time saving,
effectiveness
patient safety - reduction in errors

Question 3

what are some targets of drugs in the body ?

Answer 3

cellular
proteins
receptors
ion channels
enzymes
transport proteins

Question 4

what are the factors of pharmacokinetics ?

Answer 4

absorption
distribution
metabolism
excretion

Question 6

what is absorption in pharmacokinetics ?

Answer 6

the movement of drug into the body

Question 7

which route does not require absorption ?

Answer 7

IV

Question 8

what is distribution in pharmacokinetics ?

Answer 8

the movement of drugs around the body

Question 9

what is elimination of pharmacokinetics ?

Answer 9

the irreversible removal of drug from the body

Question 10

what are the 2 parts of elimination in pharmacokinetics ?

Answer 10

metabolism
excretion

Question 11

what is metabolism of pharmacokinetics ?

Answer 11

destruction of the drug by chemical alteration

Question 12

what is excretion of pharmacokinetics ?

Answer 12

removal of the drug from the body in the kidneys or bile

Question 13

how can drug interactions affect the absorption of drugs ?

Answer 13

chelation/ complexes - insoluble complexes not absorbed
change of GI pH
effects on gastric motility
food effects

Question 14

how is metabolism affected in drug interactions /

Answer 14

P450 inhibitors and inducers

Question 15

what are some examples of enzyme inducers ?

Answer 15

rifampicin
phenytoin
carbamazepine
COCP
theophylline

Question 16

what are some examples of enzyme inhibitors ?

Answer 16

allopurinol
azathioprine
fluconazole
warfarin
grapefruit juice
ciclosporin

Question 17

what class is haloperidol ?

Answer 17

first generation antipsychotic

Question 18

what are some indications for haloperidol ?

Answer 18

schizophrenia
acute delirium
severe manic or agitated episodes
nausea and vomiting

Question 19

what are some side effects of haloperidol ?

Answer 19

depression
headache
nausea
vision disorders
neuromuscular dysfunction

Question 20

what are some contra-indications of haloperidol ?

Answer 20

CNS depression
congenital long QT syndrome
lewy body dementia
parkinsons disease

Question 21

what is the indication for macrogol ?

Answer 21

chronic constipation

Question 22

what are the contra-indications for macrogol ?

Answer 22

ileus
intestinal obstruction / perforation
severe IBD
toxic megacolon

Question 23

what are some common side effects of macrogol ?

Answer 23

flatulence
GI discomfort
nausea and vomiting

Question 24

what drug class is macrogol ?

Answer 24

osmotic laxative

Question 25

what class of drug is alendronate ?

Answer 25

bisphosphonate

Question 26

what are the indication for alendronate ?

Answer 26

osteoporosis

Question 27

what are some side effects of alendronate ?

Answer 27

GI disorders joint swelling vertigo

Question 28

what are the indications of colecalciferol ?

Answer 28

vitamin D deficiency

Question 29

what are some side effects of colecalciferol ?

Answer 29

abdominal pain headache hypercalcaemia nausea

Question 30

what are the indications for zopiclone ?

Answer 30

insomnia

Question 31

what are some side effects of zopiclone ?

Answer 31

dry mouth bitter taste anxiety headache confusion

Question 32

what class of drug is zopiclone ?

Answer 32

non-benzodiazepine hypnotic and sedative

Question 33

what is the indication for co-careldopa ?

Answer 33

parkinsons disease

Question 34

what class of drug is co-careldopa ?

Answer 34

dopamine precursor

Question 35

what are the indications for ropinerole ?

Answer 35

adjunct in parkinsons disease restless leg syndrome

Question 36

what class of drug is ropinerole ?

Answer 36

dopamine receptor agonist

Question 37

what drug class is senna ?

Answer 37

stimulant laxative

Question 38

what are the indications of senna ?

Answer 38

constipation

Question 39

what are some indications of lorazepam ?

Answer 39

anxiety - short term acute panic attack conscious sedation for procedures

Question 40

what are some side effects of lorazepam ?

Answer 40

apnoea asthenia coma dishinhibtion extra-pyramidal symptoms memory loss slurred speech

Question 41

what drug class is lorazepam ?

Answer 41

benzo