Pharmo Exam 4 Flashcards by Amel Gaz

Q

Penicillin mechanism

A

ruptures cell wall

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Q

Aminoglycosides mechanism

A

alter cell membrane

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Q

Tetracycline mechanism

A

interferes with nucleic acid metabolism

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Q

cephalosporin mechanism

A

ruptures cell wall

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Q

fluoroquinolones mechanism

A

interfere with nucleic acid metabolism

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Q

macrolides mechanism

A

alter cell membrane

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Q

polypeptides mechanism

A

ruptures cell wall

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Q

chloromphenicol mechanism

A

interfere with nucleic acid metabolism

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Q

sulfonimides mechanism

A

interfere with nucleic acid metabolism

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Q

metonidazole mechanism

A

ruptures cell wall

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Q

penicillin action

A

cidal

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Q

aminoglycosides action

A

cidal

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Q

tetracyclines action

A

static

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Q

cephalosporins action

A

cidal

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Q

fluoroquinolones action

A

cidal

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Q

macrolides action

A

cidal or static

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Q

polypeptides action

A

cidal

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Q

chloromphenicol action

A

static

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Q

sulfonimides action

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A

static

Q

metronidazole action

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A

cidal

Q

Penicillin spectrum

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A

narrow gram +

Q

Aminoglycosides spectrum

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A

narrow gram -

Q

tetracycline spectrum

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A

broad

Q

cephalosporin spectrum

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A

narrow gram +

Fluoroquinolones spectrum

broad

Macrolides spectrum

narrow gram + cocci

Polypeptides spectrum

narrow +/-

Chloromphenicol spectrum

broad

Sulfonimides spectrum

broad

Metronidazole spectrum

broad

Macrolide elimination

kidney and bile

aminglycosides adversive side effects

nephrotoxic, ototoxic

which can you not give to ruminants

tetracyclines

bad reactions of tetracyclines

brown teeth, bind to calcium in milk, nephrotoxic

cephalosporines bad effects

nephrotoxic in large doses, +/- skin rxn

macrolide side effects

gi upset, skin reaction

polypeptide bad reaction

toxic when given systemically

sulfonamides bad reactions

crystaluria, hypoproteinemia, -/+ skin reactions

first group of antimicrobials used

sulfonimides

heaviest used in the 50s

tetracycline

most toxic aminoglycoside

neomycin

most broadspectrum aminoglycoside

amikancin

route of polypeptide

topical

CPHC bad effects

gi upset, hepatic toxicity

fungizone administered

iv