PhysioLec: NMJ

Question 1

TRUE OR FALSE: Serotonin is formed by the hydroxylation & decarboxylation of Tryptophan and is present in blood platelets, GI tract & brainstem.

Answer 1

True

Question 2

TRUE OR FALSE: Decrease in Ca++ presynaptically explains
habituation.

Answer 2

True

Question 3

TRUE OR FALSE: Kainate receptors are metabotropic receptors.

Answer 3

False

Question 4

TRUE OR FALSE: Histamine comes from Histidine.

Answer 4

True

Question 5

TRUE OR FALSE: Long-term memory can be explained by long-term potentiation.

Answer 5

True

Question 6

TRUE OR FALSE: The NMJ of smooth muscles have junctional folds.

Answer 6

False

Question 7

TRUE OR FALSE: ACh is formed from the combination of choline & acetate

Answer 7

False

Question 8

TRUE OR FALSE: The NMJ of skeletal muscles contain only one
neurotransmitter.

Answer 8

True

Question 9

TRUE OR FALSE: Mechanical response in muscle starts prior to the electrical response.

Answer 9

False

Question 10

TRUE OR FALSE: Norepinephrine comes from the amino acid Phenylalanine.

Answer 10

False

Question 11

TRUE OR FALSE: Studying in a room with closed window blinds can lead to habituation.

Answer 11

True

The stimulus is benign so the response of the post-synaptic cell will be decreased.

Question 12

TRUE OR FALSE: Having more specific receptors for a neurotransmitter makes them more selective to the transmitter.

Answer 12

True

Question 13

TRUE OR FALSE: Histamine is released by mast cells (heparin-containing cells) and is also released by the posterior hypothalamus.

Answer 13

True

Question 14

TRUE OR FALSE: Neurons that uses epinephrine as a neurotransmitter are called epinephergic neurons.

Answer 14

False

Question 15

TRUE OR FALSE: GABA B receptors are metabotoropic receptors that act via G – protein to increase K+ conductance. Potassium exits the postsynaptic cell and inhibits it

Answer 15

True

Question 16

TRUE OR FALSE: The partial, non-propagated potential at the NMJ of skeletal muscle is called an EPSP

Answer 16

False

Question 17

TRUE OR FALSE: Post-synaptic accumulation of Ca++ explains
long-term potentiation.

Answer 17

True

Question 18

TRUE OR FALSE: Epinephrine has more affinity to the α receptors.

Answer 18

False

Question 19

TRUE OR FALSE: End-plate potentials always produce a propagated action potential in skeletal muscles.

Answer 19

True

Question 20

TRUE OR FALSE: To inhibit a skeletal muscle, inhibitory end-plate
potentials will be generated at the NMJ

Answer 20

False

Question 21

TRUE OR FALSE: GABA A receptors are ionotropic receptors and act at Cl- channels. Chloride enters and hyperpolarizes the cell
which inhibits the post synaptic cell.

Answer 21

True

Question 22

TRUE OR FALSE: Feeling tired and sleepy at the end of the day,
the neurotransmitter secreted is Serotonin.

Answer 22

True

Question 23

TRUE OR FALSE: Glycine is excitatory in the brain but inhibitory in the spinal cord. It acts by an increase in Cl- conductance

Answer 23

True

Question 24

TRUE OR FALSE: The NMJ of smooth and cardiac muscles have
varicosities.

Answer 24

True

Question 25

TRUE OR FALSE: Stimulating the AMPA & kainate receptors can ‘kick off’ the Mg++ block of the NMDA.

Answer 25

True

Question 26

TRUE OR FALSE: Aspartate is one of the major inhibitory neurotransmitters in the brain.

Answer 26

False

Question 27

They have the inability to maintain contraction. A. EATON LAMBERT SYNDROME B. MYASTHENIA GRAVIS C. NONE

Answer 27

B. MYASTHENIA GRAVIS

Question 28

They are weak at first then become near normal strength. A. EATON LAMBERT SYNDROME B. MYASTHENIA GRAVIS C. NONE

Answer 28

A. EATON LAMBERT SYNDROME

Question 29

Antibodies against presynaptic ACh vesicles A. EATON LAMBERT SYNDROME B. MYASTHENIA GRAVIS C. NONE

Answer 29

C. NONE

Question 30

Antibodies against presynaptic voltage-gated Ca++ channels. A. EATON LAMBERT SYNDROME B. MYASTHENIA GRAVIS C. NONE

Answer 30

A. EATON LAMBERT SYNDROME

Question 31

Antibodies against ACh nicotinic receptors. A. EATON LAMBERT SYNDROME B. MYASTHENIA GRAVIS C. NONE

Answer 31

B. MYASTHENIA GRAVIS