Physiological Changes of Aging Flashcards

1
Q

Changes in cardiovascular circulation

A
  • Decrease contractibility, increase fat and collagen
  • myocardial hypertrophy (esp. left ventricle)
  • decrease cardiac reserve
  • thickening and fibrosis of heart valves
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2
Q

What happens in cardiovascular circulation?

A
  • decrease cardiac output
  • decrease blood flow to vital organs and periphery
    -Incomplete closure of valves, therefore heart murmurs
  • Baroreceptors in the aortic arch & carotid sinus become less sensitive
  • Arterial blood vessels thicken, becoming more rigid and loosing elasticity
    -Blood supply to various organs decreases & peripheral resistance increases. Rigid arteries contribute to CAD, HTN & PVD
  • Lower extremity edema develops, risk for DVTs
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3
Q

Changes in cardiovascular electricity

A
  • Cellular aging and fibrosis, changes the conduction system

- There is a ↓ number of pacemaker cells in SA node (by 75, only 10% of normal # of pacemaker cells)

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4
Q

What happens in cardiovascular electricity?

A

-There is a ↓ in amplitude of the QRS complex & lengthening of the PR, QRS & QT intervals
(these are defined as cardiac arrhythmias = atrial fibrillation, atrial flutter, etc.)
-Sinus bradycardia, premature beats

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5
Q

Sinus Bradycardia

A
Rate			˂ 60
Regularity		regular rhythm
P wave			normal, upright, uniform
PR interval		0.12 – 0.20 seconds
QRS			0.06 – 0.10 seconds
T wave			normal
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6
Q

Atrial Fibrillation

A

Rate atrial rate 350–450, vent rate varies with AV conduction
Regularity irregularly irregular
P wave no P waves, replaced by fine fibrillatory waves
PR interval indiscernible
QRS 0.06 – 0.10 seconds
T wave indiscernible

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7
Q

Structural changes in respiratory system

A
  • ↑ anteroposterior diameter of the thoracic cage
  • ↓ elastic recoil of the lung and ↓ chest wall compliance
  • Alveolar ducts and bronchioles enlarge and the number of alveoli decreases
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8
Q

What happens in structural changes of respiratory system

A
  • Barrel chest appearance, displacement of apical pulse
  • ↓ vital capacity, ↑ residual volume; therefore diminished breath sounds particularly at lung bases
  • Reduced overall efficiency of ventilatory exchange, therefore a decrease in PaO2
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9
Q

Changes in respiratory defenses

A
  • A decline in cell-mediated immunity and formation n of antibodies (↓ in alveolar macrophages)
  • ↓ cough force and less functional cilia
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10
Q

What happens in changes in respiratory defenses

A
  • ↑ risk of respiratory infections

- ↓ cough effectiveness and ↓ secretion clearance

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11
Q

Changes in respiratory control

A
  • ↓PaO2

- ↑PaCO2

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12
Q

What happens in changes of respiratory control

A
  • ↓ response to hypoxemia
  • ↓ response to hypercapnia
  • Ability to maintain acid-base balance ↓
  • In addition, retained secretions, excessive sedation, or positioning that impairs chest expansion may substantially alter PaO2 or SpO2 values
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13
Q

Changes in muscle, ligaments, and tendons

A
  • Muscle fibers decrease and have atrophy of muscle cells
  • Loss of elasticity and ↓ flexibility in ligament/tendons
  • Gradual reduction in the speed and power of skeletal or -voluntary muscle contractions
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14
Q

What happens in changes in muscle, ligaments, and tendons

A
  • ↓ muscle mass, tone & strength
  • Movement is more rigid, changes in gait and ↓ in agility
  • Slowed reaction time and reflexes
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15
Q

Changes in joints

A
  • Deterioration of joint cartilage

- Loss of water from disk between vertebrae, therefore narrowing of intervertebral spaces

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16
Q

What happens in changes in joints

A
  • Osteoarthritis; pain & joint stiffness, ↓ ROM, and crepitation on movement
  • Loss of height from disk compression
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17
Q

Changes in bones

A
  • ↓ in bone density
  • Decalcification of bones
  • Osteoporosis
  • Posture and structural changes (deformities such as dowager’s hump)
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18
Q

Changes in mouth

A
  • Loss of teeth
  • ↓ taste buds, ↓ sense of smell
  • ↓ salivary production
  • Atrophy of gingival tissue
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19
Q

What happens in changes of mouth

A
  • Difficulty chewing may lead to decrease in appetite
  • Diminished sense of taste (esp. with salty & sweet) may leads to excessive use
  • Diminished sense of taste & smell may result in ↓ appetite and weight loss
  • Dry oral mucosa
  • Poor-fitting dentures
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20
Q

Changes in esophagus or stomach

A
  • ↓ tone & motility of the esophagus
  • Lower esophageal sphincter pressure is decrease (or becomes incompetent)
  • ↓ gastric acid secretion, atrophy of gastric mucosa and less resistant to damage
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21
Q

What happens in changes in esophagus or stomach

A
  • ↓ esophageal peristalsis, therefore propulsion of food is less effective, complaints of dysphagia & heartburn (GERD)
  • Entry of food is delayed into the stomach, causing a premature feeling of fullness
  • Food intolerance
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22
Q

Changes in small intestine

A
  • ↓ motility and ↓ secretions of digestive enzymes in the small intestines
  • Liver - ↓ hepatic blood flow, ↓ in actual size, and ↓ in production of enzymes
  • Pancreas - ↑ fibrosis, decreased secretion of enzymes and hormones
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23
Q

What happens in changes in small intestines

A
  • Slowed intestinal transit, delayed absorption
  • Impaired drug metabolism
  • Impaired fat absorption and decreased glucose intolerance
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24
Q

Changes of the bottom of the barrel or your ass

A
  • ↓ anal sphincter tone and nerve supply to rectal area
  • ↓ muscle tone, ↓ motility in large intestines
  • ↑ transit time
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25
What happens in changes of your ass
- Fecal incontinence - Flatulence, abdominal distension - Constipation, fecal impaction
26
Changes in kidneys
- ↓ number of nephrons, ↓ function of loop of Henle and tubules - ↓ renal blood flow, ↓ glomerular filtration rate
27
What happens in changes of the kidneys
- A reduced ability to concentrate urine and conserve water (potential for hydration is increased) - ↓ creatinine clearance – excretion of toxins/drugs is decreased, ↑ BUN level
28
Changes in urinary bladder
- ↓ elasticity and muscle tone of bladder, weakening of urinary sphincter - ↓ ability of bladder to completely empty - ↑ residual urine
29
What happens in changes of the urinary bladder
- Stress incontinence, frequency, urgency - Nocturia - Retention
30
Changes in male reproductive system
- ↓ testosterone levels - Prostate enlarges - Testes atrophy - ↓ sperm count - ↓ rate & force of ejaculation - ↑ refractory period after orgasm
31
Changes in female reproductive system
- ↓ estrogen levels - Ovaries, uterus, cervix slowly atrophy - ↓ in vaginal secretions - Vaginal pH becomes alkaline - Cessation of menses - ↑ refractory period after orgasm
32
Changes in skin
- ↓ subcutaneous fat, ↓ elasticity, collagen stiffens and ↓ thickness of epidermis - ↓ sebaceous and sweat gland activity - Skin tissue fluid ↓
33
What happens in changes of skin
- Appearance of wrinkles - Tendon, veins & knuckles are more prominent - Skin has transparent, tissue-like appearance and is fragile (prone to breakdown) - Day flaking skin with minimal to no perspiration - ↓ skin turgor (dehydration) - ↑ melanocytes - ↓ blood supply & sensory receptors in skin - ↑ capillary fragility - ↓ proliferative capacity - Lentigines on face & back of hands - Skin is cool to touch, ↓ awareness of pain, touch, temperature & vibration - Evidence of bruising - ↓ rate of wound healing
34
Changes in hair
-Melanin in hair is decreased -↓ oil -↓ density of hair follicles Cumulative androgen effect, ↓ estrogen levels
35
What happens in changes of hair
- Hair colour becomes gray or white - Dry, coarse hair with scaly scalp - Thinning/loss of hair - Older men have more nasal hair and hair in ears - Older women have increase facial hair
36
Changes in nails
- ↓ blood supply to nail beds | - Longitudinal ridges/striations increased
37
What happens in changes of nails
- Thick, brittle nails with diminished nail growth | - Nails prone to splitting – potential for fungal infection
38
Changes in central nervous system
- Reduction in cerebral blood flow - Brain weight decreases from loss of neurons - The number of synapses, axons and dendrites also decreases
39
What happens in changes of central nervous system
- Alterations in selected mental functions - Mild memory impairment - Intellectual performance without brain dysfunction remains constant, however the performance of tasks may take longer (fluid intelligence)
40
Changes in the nervous system
- ↓ neurotransmitters and ↓ in rate of nerve cell conduction impulses - ↓ motor response and ↓ reflexes - Decrease in efficiency of temperature regulating mechanism
41
What happens in changes of the nervous system
- Monoamine oxidase and norepinephrine production often increase with age while serotonin production may go up or down (depression may be the result) - Sluggish reflexes and ↓ reaction time (impaired response to imbalance = falls) - Less able to adapt to extremes in environmental temperatures
42
Changes in peripheral nervous system
- Diminished sense of touch and vibration | - Kinesthetic sense or proprioception (one’s position in space) is altered
43
What happens in changes of peripheral nervous system
- Decreased sensitivity is translated into delayed reactions to things such as hot surfaces, significant increasing the risk for burns - If one is less aware of body position and has less tactile awareness, the risk for falling is dramatically increased
44
Changes in sleep
- Modification of hypothalamic function, loss of deep sleep | - REM sleep is decreased in the elderly over 85
45
What happens in changes of sleep
- Increased frequency of spontaneous awaking (sleep is lighter) - Interrupted sleep, insomnia, tiredness
46
Changes in visual system
-Elasticity and tone of eyelid muscles is decrease and have loss of orbital fat (shrunken appearance of eyes) -Presbyopia – gradual decline in the ability to focus on close objects -Lens becomes less elastic, thickened, more dense and visual acuity decreases as the lens becomes more opaque (↑ sensitivity to glare) -Pupils become smaller and slower to react to changing levels of illumination -↓ colour perception especially to blue, green and violet -Tear production is decrease (dry eyes) -↓ peripheral vision & distorted depth perception ↑ risk for glaucoma
47
Changes in auditory system
- Presbycusis – hearing loss, ↓ ability to hear high-pitched sounds - ↑ production of and drier cerumen (ear wax) results in impacted wax - Atrophic changes of tympanic membrane - Hair cells degeneration, neuron degeneration in the auditory nerve and central pathway, reduced blood supply to cochlea - ↓ sensitivity to high-pitched sounds - Alterations in balance and body orientation due to less effective vestibular apparatus in semicircular canals
48
Changes in immune system
- Antibody function is impaired - Response to foreign antigens decrease - Thymus decreases in size and activity - Both T and B cells show deficiencies in activation - Increased prevalence of autoimmune disorders - Therefore: susceptibility to infections increases
49
Changes in endocrine system
- ↓ production of TSH - ↑ incidence of hypothyroidism - ↑ levels of PTH - ↑ calcium resorption (loss) from bone - ↑ glucose intolerance and ↓ sensitivity to insulin (contributes to increase incidence of DM) - Adrenal glands’ secretion of glucocorticoids decrease by -25% by age 70 (involved in reactions to stress) - Plasma renin levels and aldosterone concentrations decline (may have fluid and electrolytes abnormalities) - ↓ sensitivity of renal tubules to ADH (fluid deficits) - Defects in thermoregulation – poor perception of changes in temperature - Reduction of febrile response (fever not always present with infectious process)
50
Nursing interventions to promote drug therapies
- Monitor clinical responses and plasma drug levels to provide a rational basis for dosage adjustment - Employ the simplest regimen possible - Monitor for drug-drug interactions - Periodically review the need for continued drug therapy - Encourage the patient to dispose of expired medications
51
How to promote compliance
- Clear & concise verbal & written instructions - Suggest a dosette box - Evaluated if patient able to self-administer or not
52
Cardiovascular implications
- Irregular cardiac rhythms - Decrease capacity for physical work - Risk of orthostatic hypotension - Circulatory changes in periphery (PVD) - Possible anemia, dehydration
53
Cardiovascular interventions
- Monitor pulses (ECG) - Monitor for weakness, SOB, dizziness, chest pain - Assess BP supine vs. standing - Encourage rising slowly when getting up - Neurovascular assessment - Monitor labs –hemoglobin, hematocrit
54
Respiratory implications
- Exercise tolerance diminished - Cough and deep breathing diminished, dyspnea - Mucus thickens - Decreased ability to bring up secretions - Increase risk for infections
55
Respiratory interventions
- Monitor exercise, tailor to patient - Monitor RR, lung sounds, O2 saturation, encourage inspirometer, DB&C - Promote adequate fluid intake to keep secretions liquefied - Encourage influenza and pneumonia immunization
56
Musculoskeletal implications
- Muscle atrophy, ↓ strength - ↓ ROM and flexibility - ↓ ability to perform ADLs - Pain and joint stiffness - Changes in gait - Increase risk of falls
57
Muscoloskeletal interventions
- Exercise as per patient’s tolerance - Passive ROM, consult with PT - ADL assessment scales - Pain scale, pharm/non-pharm strategies - Encourage use of walking aids - Protect patient from injury (safe environment assistive device) - Morse fall scale, Timed up-and-go test
58
Consequences of immobility
- Muscle atrophy - Orthostatic hypotension - Recurrent sepsis - Pressure sores - Contractures - Risk for falls
59
Changes in sleep interventions
- Establish a bedtime ritual & wake-up time - Avoid long naps during the day - Avoid caffeine products after 16:00 - Relaxation methods
60
Nutrition implications
- ↓ taste can make eating less enjoyable - Difficulty chewing or swallowing - Possible malnutrition - Diabetes increasingly prevalent - Heartburn, indigestion & food intolerance
61
Nutrition interventions
- Promote herb seasoning & salt replacement - Cut food into small bites - Food diary, monitor albumin, BMI (weight) - Encourage smaller meals - Reduce acidic/spicy foods - The Nestle Mini Nutritional Assessment tool
62
Fluid and electrolytes implications
- Fluid imbalances - Risk of hypernatremia - Risk of hypokalemia
63
Fluid and electrolytes interventions
- Promote adequate fluids - Monitor I/Os, monitor for signs of fluid overload or dehydration - Monitor electrolytes
64
Urinary implications
- Decrease in GFR affects excretion of drugs - Nocturia - Urinary retention, risk of UTI - Urgency and frequency is common - Prone to fluid and electrolyte imbalances
65
Urinary interventions
- Monitor for toxicity – Cr clearance - Limit fluids prior to bed - Urinary analysis, promote cranberry juice - Encourage kegel exercises, absorbent products, assistive toileting equipment - Monitor I/Os, weight, electrolytes
66
Bowel implications
- Decrease motility in large intestines | - Risk for constipation, fecal impaction
67
Bowel interventions
- Explore bowel pattern - Explore diet - Encourage fluids & fiber intake with mobilizing - Assess need for stool softener
68
Protection implications
- Dry, fragile skin, prone to abrasions and skin lacerations - Decrease rate of wound healing - Less ability to control temperature - Risk for infections
69
Protection interventions
- Prevent skin breakdown - Positioning, lotions, bed sheet to be taut, Braden Scale - Keep extremities warm & room at moderate temperature - Monitor WBC, obtain baseline temp., encourage immunization
70
Neurological implications
- Slowed reaction time & reflexes (falls) - Kinesthetic sense is altered (falls) - Memory impairment - Fluid intelligence changes (takes longer to perform task)
71
Neurological interventions
- Schedule task so as to give patient enough time - Ensure safety (environment) - Offer orienting, leave notes - Allow time for the patient to process questions
72
Visual implications
- Presbyopia - Decreased capacity to adjust to changing levels of illumination - Diminished night vision - Increased sensitivity to glare - Decreased depth perception
73
Visual interventions
- Encourage eye exams and use of eye glasses - Write clearly and largely - Ensure appropriate lighting - Nightlights - Encourage non-glare lighting - First and last step of stairs can be marked
74
Auditory implications
- Generalised hearing loss - Risk of social isolation - Decrease in sebaceous gland causing cerumen to become dry - Alteration in balance & body orientation
75
Auditory interventions
- Reduce background noise, speak closely and clearly - Check ears for impacted wax and infection - Walking aids – walkers, canes
76
Taste, smell and sensations implications
- ↓ taste buds - ↓ sense of smell - Reduced tactile sensation, therefore ↓ ability to sense pressure, pain & temperature
77
Taste, smell, and sensation interventions
- Promote herb seasoning & salt replacement to enhance flavour - Promote safe environments, smoke detectors - Reduce environmental risks i.e. risk of burns
78
Teaching strategies
- Make sure patient is ready to learn - Sit facing the patient so that lips and facial expressions are readily seen by patient - Speak slowly - Keep your tone of voice low - Give the patient enough time to response - For concentration, focus on a single topic at a time - Keep environmental distractions to a minimum - With patient permission, invite another member of household to participate - Use auditory, visual, and tactile cues to enhance learning - Ask for feedback to ensure information has been understood - Refer to patient’s past experienced (connect new with old) - Compensate for physical discomfort and sensory alterations if needed