Physiology

Question 1

Diffusion

Answer 1

permeability constant: Kp= solubility / √MW

Q = Kp x (Area/thickness) x (C1-C2)

Question 2

Total blood volume

Answer 2

Plasma V x100 / (100 - HCT)

Question 3

Measure fluid compartments

Answer 3

volume of compartment = mass of indicator / concentration in compartment

Question 4

Osmotic pressure (van’t Hoff)

Answer 4

π = RTC

C = osmolality (mosm/kg H20

Question 5

Plasma osmolality

Answer 5

2 x [Na] +[glucose] + [urea}

Question 6

Gibbs-Donnan

Answer 6

[cation]a x [anion]a = [cation]a x [anion]b

Question 7

Nerst

Answer 7

capillary wall potential (mV) = RT /ZF loge conc in /Conc out

Question 8

Starling forces

Answer 8

π = colliod osmotic pressure
P = hydrostatic pressure
int = interstitial
c = capillary

Pressure gradient = (Pc + πint) - (Pint + πc)

Rate of filtration = K (Pc + πint) - (Pint +πc)

Question 9

Stroke volume

Answer 9

SV = EDV - ESV

Question 10

Ejection fraction

Answer 10

SV/ EDV

Question 11

Cardiac output

Answer 11

CO = HR xSV

Question 12

Cardiac Index

Answer 12

CO / BSA

Question 13

SVR

Answer 13

SVR = MAP - CVP /CO x80

Question 14

MAP

Answer 14

MAP - CVP = CO x SVR

Question 15

Fick

Answer 15

CO = V02 / (Ca02 - Cv02)

Question 16

Bohr

Answer 16

Vd/Vt = PAC02 -PeCO2/PAC02

Question 17

Alveolar gas equation

Answer 17

PA02 = Pi02 - (PAC02/R)

Question 18

RER

Answer 18

R = VC02/V02

Question 19

Shunt

Answer 19

Qs/Qt = Cc02 - Ca02 / Cc02 - Cv02

Question 20

Compliance

Answer 20

V/P

1/ resp compliance = 1/ lung compliance + 1/ wall compliance

Question 21

Oxygen content

Answer 21

([Hb] x sats x 1.34) + (0.023 x Pa02) kpa

Question 22

Clearance

Answer 22

urine conc x urine flow / plasma conce

Question 23

pKa

Answer 23

pH = pk + log (HC03) / (H2CO3)

Question 24

CPP

Answer 24

CPP = MAP - (ICP +CVP)