Flashcards in Physiology Block 3 Week 16 15 Endocrine Case: Thyroid Case Deck (6)
How do you confirm diagnosis of Graves Disease?
How do you treat it?
Graves Disease is result of an autoimmune response which activates the TSH receptor on thyroid follicle cells resulting in excessive hormone production
-give radioactive iodine, taken up by thyroid and melts it down
-can block organification (incorporation of iodine into thyroglobulin for production of thyroid hormone) with medication
-can remove thyroid (last choice)
Components of Graves Disease
Thyromegaly and Hyperthyroidism
Risk Factors for Graves Orbitopathy
Use of radioactive iodine therapy
Nail grow away from the bed
Loss of skin pigmentation thought to be due to autoimmune damage of melanocytes