Physiology Immune System Flashcards

(45 cards)

1
Q

Immune system physical barriers

A

Skin

Mucous linings

Ciliated epithelium

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2
Q

Immune system chemical barriers

A

Lysozyme

Acids

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3
Q

Immune system mechanical barriers

A

Physical removal of pathogens

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4
Q

Innate immunity

A

Immediate response, responds to a range of signals

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5
Q

Adaptive immunity

A

Stronger response, attack specific pathogen or antigen and have memory of last illnesses

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6
Q

Four step in immune response

A

Detect and identify

Communicate with other immune cells

Recruit other immune cells and coordinate response

Destroy or suppress invader

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7
Q

Lymphoid tissues

A

Bone marrow, thymus, lymph nodes, spleen, appendix, and tonsils

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8
Q

Thymus

A

Glandular organ near the heart which activates T lymphocytes

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9
Q

Bone marrow

A

Blood-producing tissue located in certain bones

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10
Q

Spleen

A

Filter for the blood

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11
Q

Red pulp

A

Macrophages remove old and damaged red blood cells and trap and destroy infectious agents

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12
Q

White pulp

A

Lymphocytes

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13
Q

Lymphatic vessels

A

Collect fluid that has filtered out of the blood into the tissues and returns it to circulation

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14
Q

Lymph nodes

A

Permanent aggregate of immune cells that filter out dead cells and antigens to present to lymphocytes

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15
Q

Granulocytes

A

Eosinophils, basophils and mast cells, and neutrophils

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16
Q

Agranulocytes

A

Monocytes and macrophages

Lymphocytes

Dendritic cells

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17
Q

Morphological grouping

A

Granulocytes carry granules laden with killer chemicals

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18
Q

Phagocytes

A

Engulf and digest invaders

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19
Q

Cytotoxic

A

Attack and kill

20
Q

Antigen-presenting cells

A

Display foreign particles on surface

21
Q

Mononuclear phagocytes system

A

Macrophages in tissue and parent monocytes in blood

22
Q

Eosinophils

A

Allergic reactions and parasitic diseases

23
Q

Basophils and mast cells

A

Release histamine, inflammation, and innate immunity response

24
Q

Neutrophils

A

Phagocytic and release cytokines and inflammatory mediators

25
Monocytes
Mature to tissue macrophages, phagocytic, and antigen-presenting cells
26
Lymphocytes
Acquired immunity
27
Dendritic cells
Found at interface between external and internal environments and antigen-presenting cells
28
Myeloblast
Immature white blood cell in the bone marrow and becomes granulocytes
29
Lymphoblast
Precursor of lymphocytes
30
Development of T lymphocytes
Migrate from bone thymus to mature
31
Development of B lymphocytes
Mature in bone marrow
32
Development of natural killer cells
Develop in bone marrow and other tissues
33
What causes the development of lymphocytes
Adaptive immune response
34
Chemotaxins
Stimulate increased inflammatory cell migration in the tissues and increases the inflammatory cascade
35
Opsonins
Facilitate recognition, binding, ingestion, and killing of microorganisms by phagocytes
36
Phagocytosis
Ingest foreign cells and chemicals
37
Inflammation
Infection or tissue damage that stimulates local non-specific reactions
38
Innate immunity macrophage
Attracted to infection site by chemicals from dying cells After ingesting, they wear pieces of it so other immune system cells know what to target
39
Natural killer cells
Secrete interferons Protect against viral infections, cancer Kill cells by using perforin to make holes in cell membrane of target cell which then lyse the cell
40
Beneficial roles of inflammation
Attract immune cells and chemical mediators Create physical barriers to prevent infection spread Promote tissue repair
41
Acute-phase proteins
Help prevent tissue damage Increase supply during infection and inflammation
42
Interleukins
Communication between leukocytes through fever, increased vessel permeability, and stimulation of liver to produce acute phase proteins
43
Bradykinin
Pain and swelling
44
Complement proteins
Complement work of antibodies in destroying bacteria
45
Membrane attack complex
Complement proteins insert into membrane, creating pores Water and ions enter pathogen through pores Cell swells and lyses