Physiology of the Spinal Cord Flashcards

(31 cards)

1
Q

what are the physiological functions of the spinal cord?

A

initial processing of somatosensory input by the CNS

primary processing of motor output by CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are spinal nerves?

A

highways for both somatosensory information traffic to the spinal cord (afferent) and motor information from the spinal cord to muscles (effect)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is the difference between sensation and perception?

A
sensation = detection by receptors
perception = interpretation by spinal cord and brain circuits
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are receptors?

A

neurons specialised in transduction of energy generated by external stimuli
specific for a narrow range of input

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what do neurons in sensory signal systems signal events by?

A

spatial
rate
temporal codes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

impact of convergence and divergence

A

high spatial resolution required: low convergence
detection of weak signals: high convergence
input used for complex/multiple functions: divergence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

2 main kinds of 1st order sensory neurons

A

bare nerve endings - neuron detects stimulus (most common)

mechanoreceptors - detect stimulus then transmit signal to sensory neuron (found in sense organs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

A beta fibre 1st order neurons

A

for touch, pressure and vibration
wide diameter, fast
receptor type: mecanoreceptors e.g. Merkell’s cells, Ruffini end-organs, Pacinian corpsucles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

A delta fibre 1st order neurons

A

for touch, pressure, vibration and pain
medium diameter and speed
bare nerve endings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

C fibre 1st order neurons

A

for pain
thin diameter, slow
bare nerve endings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

cutaneous mechanosensory receptors

A

Meissner’s corpuscle
Merkel disc
Ruffini’s corpuscle
Pacinian corpuscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what do Meissner’s corpuscles detect?

A

light tough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what do Merkel discs detect?

A

mechanical pressure and position

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what do Ruffini’s corpuscles detect?

A

tension, folding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what to Pacinian corpuscles detect?

A

vibration, gross pressure changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how can sensory stimulation be discriminated?

A

different types of receptors for same modality
spatial distribution of receptors
windows of response intensity

17
Q

what is 2 point discrimination?

A

measure variation in sensitivity of tactile discrimination as a function of location on the body surface
if there is a higher density of mechanoreceptors, smaller distance at which 2 tactile stimuli can be discriminated

18
Q

where is mechanoreceptor density greatest?

A

on hands on face

allows detection of stimuli at greater spatial resolution

19
Q

what is the motor system?

A

our muscles and neurons that command them

system that gives rise to behaviour

20
Q

what is the simplest motor system?

A

spinal cord can generate complex motor patterns independently of the brain

21
Q

what are lower motor neurons?

A

final common path for all signals from CNS to skeletal muscles
collected in longitudinally organised columns
each neuron receives motor fibres through more than one ventral root

22
Q

each (lower motor neuron) column …

A
  • contains larger alpha and smaller gamma motor neurons to one muscle
  • extends through more than one segment of the cord
23
Q

what is the difference between alpha and gamma motor neurons?

A

alpha: thick axon, high conductance velocity
gamma: thin axon, low conductance velocity

24
Q

what can destrution of a single ventral root/spinal nerve cause?

A

muscle weakness = paresis

not paralysis

25
what is a motor unit?
a single motor neuron and muscle fibre it innervates
26
what are the simplest reflex responses based on?
an interaction between proprioceptive sensory input and a motor unit
27
what do proprioceptive sensory neurons detect?
muscle spindles - negative feedback to regulate muscle length golgi tendon organs - negative feedback to regulate muscle tension
28
an example of a monosynaptic reflex pathway
stretch reflex - negative feedback loop to regulate muscle length
29
how does the monosynaptic reflex pathway work?
muscle spindle (sensory receptor) initiates reflex stretch increases afferent activity increases alpha motor neuron activity increases: muscle contracts
30
an example of a polysynaptic reflex pathway
flexion reflex
31
how does the polysynaptic reflex pathway work?
stimulation of cutaneous pain receptors in foot activation of spinal cord local circuits stimulated extremity is flexed other extremity extends to provide compensatory support