Pig Enteritis

Question 1

Other names for porcine intestinal adenomatosis (PIA) complex

Answer 1

Necroproliferative enteritis, regional ileitis, proliferative hemorrhagic enteropathy, garden hose gut, necrotic enteritis

Question 2

Characteristics of PIA complex

Answer 2

Complex syndrome displaying a variety of pathologic changes; limited to SI and LI

• PIA: thickening of intestinal mucosa
• NE: deep coagulative necrosis of adenomatous surface
• RI: granulation tissue proliferation in lamina propria and submucosa of PIA w/ hypertrophy of the muscle
• PHE: massive hemorrhage into lumen w/o visible bleeding points in the thickened proliferated mucosa

Question 3

PIA Incidence, etiology, and epidemiology

Answer 3

Incidence: increased prevalence, hi health herds
Etiology: Campylobacter -> ileal symbiont, intracellularis -> Lawsonia***
Epidemiology: Carriers; fecal/oral, 6-20wk most common but can affect all ages

Question 4

PIA Complex

Answer 4

PIA: mild CS; weight loss, decreased appetite, diarrhea
NE/RI: more severe diarrhea and weight loss
PHE: Acute hemorrhagic anemia, melena, death
Incubation 3-6wk, spontaneous recovery in 4-6wk

Question 5

PIA pathogenesis

Answer 5

Oral ingestion -> infection -> proliferation of immature glandular epithelial cells -> elongation of glands
PHE: rupture of capillaries at tips of villi
NE: Necrosis of regressing mucosa
RI: Cycles of proliferation and necrosis

Question 6

PIA Pathology

Answer 6

Usually ileum, occasionally upper colon and cecum
NE: yellow masses of friable necrotic matter
RI: Wall is smooth and rigid, lining ulcerated or granulation
PHE: SI distended w/ blood, no bleeding points noticeable, melena, anemia
Histo: Silver staining, see organisms, proliferative enteritis

Question 7

PIA Dx

Answer 7

Hx/CS
PM/Histo
“Clean herd”
DDx: Salmonella, Swine dysentery

Question 8

PIA Tx

Answer 8

OTC/CTC
Tylan
mecadox
BMD
Parenteral, food, water
Control: feed meds, pulse therapy, vaccine, cost:benefit

Question 9

Gastric ulcers definition, etiology

Answer 9

Ulceration of the pars esophagus
Incidence: 2-100% of animals @ slaughter
Etiology: Copper, stress, gastric acidity, whey feeding, corn starch, feed processing, fatty acids, Vit E, Se, finely ground feed, off feed, etc.

Question 10

Gastric ulcer CS and path

Answer 10

CS: dead, melena, wt loss, anemia, abd pain
Path:
- Acute: blood in stomach, GIT, peritonitis
- Chronic: craters

Question 11

Gastric ulcers Dx and Tx

Answer 11

Dx: Hx, CS, melena, anemia, PM, Endoscope
DDx: PHE
Tx: Cost:benefit, cimetidine, ranitidine, gastroguard
Control: check factors, feed!!