Pituatry clinical

Question 1

A hormone is?

Answer 1

secreted

bioactive messenger

Question 2

A hormone can

Answer 2

travel in blood
effect target cell
stimulate/inhibit
maintain physiological state

Question 3

how big is the thyroid gland

Answer 3

10-15g

Question 4

thyroxine is?

Answer 4

iodide + tyrosine

Question 5

thyroxine stored where

Answer 5

gland

Question 6

thyroxine secreted to

Answer 6

blood

Question 7

order, releasing factor…

Answer 7

Releasing factor
tropic hormone
target hormone
response

Question 8

name releasing factor.. Thyroid axis

Answer 8

Hypothalamus:
Thyrotropin releasing hormone
(TRH)

Pituitary:
Thyroid stimulating hormone
(TSH)

Thyroid:
Thyroxine and triiodothyronine
(T4 and T3)

End Organ(s):
Basal metabolic rate, pulse

Question 9

Hypothyroidism deficiency 1st

Answer 9

Thyroid (T3/T4)

Question 10

Hypothyroidism deficiency 2nd

Answer 10

pituitary (TSH)

Question 11

Hypothyroidism deficiency 3rd

Answer 11

Hypothalamus (TRH)

Question 12

Hypothyroidism Resistance

Answer 12

Periphery (P, BMR)

Question 13

Pituitary sits in

Answer 13

pituitary fossa

Question 14

pituitary fossa is in

Answer 14

in sphenoid bone

Question 15

Cavernous sinus contains

Answer 15

Internal carotid Artery

Question 16

Posterior Pituitary makes

Answer 16

ADH + Oxytocin

Question 17

Anterior pituitary makes

Answer 17

6 tropic hormones

Question 18

Lesion of the optic chiasm causes

Answer 18

Bitemporal hemianopia (visual field )

Question 19

bitemporal hemianopia caused by

Answer 19

optic chiasm is compressed

Question 20

Symptoms of endocrine diseases

Answer 20

Shave less freq
Libido decrease
Reduce energy
Gained weight

Question 21

Anterior pituitary is

Answer 21

Vascular network connected to hypothalamus

Question 22

Anterior pituitary hormones

Answer 22

TSH
ACTH
FSH+LH
GH
PROLACTIN

Question 23

TSH—>

Answer 23

thyroid—> thyroxine

influnces metabolic rate

Question 24

ACTH—->

Answer 24

adrenals–> cortisol

influences stress response

Question 25

FSH + LH--->

Answer 25

gonads---> testo/estadriol | sperm, ova

Question 26

GH--->

Answer 26

liver---> IGF-1 | vertical growth, bonemass, metabolism

Question 27

PRL --->

Answer 27

Breast --> lactation

Question 28

The bigger the tumour the more it..

Answer 28

compresses the stalk

Question 29

Test of hypofunction

Answer 29

Measure the pituitary and target hormone

Question 30

Endocrine evaluation

Answer 30

``` Clinical symptoms confirm abnormality of target hormone determine part of axis that's abnormal by measuring each level localise site of abnormality identify pathology ```

Question 31

What % of macro Adenomas are non secreting

Answer 31

50

Question 32

Ways in which pituitary tumours present

Answer 32

``` Mass effect Hypoventilation Incidental Hyper function Apoplexy/ haemorrhage ```

Question 33

Treatment-

Answer 33

Surveillance Surgery Medical Radiotherapy

Question 34

Principles of hormone replacement : | Goal of treating hypopituitarism is to

Answer 34

Replace hormones

Question 35

Replacement needs to

Answer 35

Recognise digital variations and natural evolution of hormones over time