Pituitary Physiology Flashcards Preview

Endocrinology > Pituitary Physiology > Flashcards

Flashcards in Pituitary Physiology Deck (12):
1

microadenoma

pituitary tumour same size as or smaller than 1cm

2

macroadenoma

more than 1cm

3

what can a non-functioning pituitary adenoma cause?

Compression on optic chiasma
Compression on other structures eg cranial nerve 3,4,6
Hypoadrenalism
Hypothyroidism
Hypogonadism
(Diabetes Insipidus)
GH deficiency

4

what are the physiological causes of raised prolactin?

breast feeding
pregnancy
stress
sleep

5

what drugs can cause a raised prolactin?

dopamine antagonists
antipsychotics
antidepressants

6

what are the pathological causes of raised prolactin?

hypothyroidism
stalk lesions
prolactinoma

7

what is acromegaly due to an excess of?

GH

8

how is acromegaly diagnosed?

IGF-1
GTT
Visual field
CT/MRI pituitary scan
Pituitary function tests

9

what is bushings syndrome due to?

excess cortisol, mineralocorticoid & androgen

10

what is bushings characterised by?

Thin Skin
Proximal myopathy
Frontal balding in women
Conjunctival oedema (chemosis)
Osteoporosis

11

name some causes of hypopituitarism

pituitary tumours
secondary metastatic lesions
local brain tumours
granulomatous diseases
trauma

12

what are the risks of testosterone replacement?

prostate enlargement
polycythaemia
hepatitis