Placenta Flashcards

(28 cards)

1
Q

The foetal and maternal circulations do not ,ix. T/F?

A

True

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2
Q

What is the name of the series of lobes into which the basal plate of the placenta is divided?

A

Cotyledons

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3
Q

What is the name of the maternal part of the placenta?

A

Basal plate

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4
Q

Dichorionic diamniotic twinning results from twinning which occurs between….?

A

Days 1-3

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5
Q

Monochorionic diamniotic twinning results from twinning which occurs between….?

A

Fays 4-8

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6
Q

Monochorionic monoamniotic twinning results from twinning which occurs between….?

A

Days 8-13

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7
Q

Conjoined twins results from twinning which occurred between days…?

A

13 and 15

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8
Q

Which layer of the embryonic part of the placenta proliferates and which layer is non-dividing?

A

Cytotrophpblast layer proliferates

Syncitiotrophoblast layer is non Dividing

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9
Q

Within which trophoblast layer do lacunae begin to form after day 8 of conception?

A

Syncitiotrophoblast

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10
Q

The lacunae of the syncitiotrophoblasts are the precursors of…?

A

Intervillous space

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11
Q

Towards the end if the second week small projections of the cytotrophoblast layer begin to expand into the syncitiotrophoblast. What do these form?

A

Primary chorionic villi

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12
Q

Extraembryonic mesoderm grows into the primary chorionic villi to form…?

A

Secondary chorionic villi

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13
Q

What happens to secondary chorionic villi to convert them to tertiary chorionic villi?

A

Small embryonic blood vessels start to grow into the villi

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14
Q

What is the function of the intervillous space of the placenta?

A

It is the site if exchange between foetal and maternal blood

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15
Q

The stroma is the villous core. What cells is it mainly composed of?

A

Fibroblast cells

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16
Q

The villous cytotrophoblast layer is only present in early pregnancy. T/F?

17
Q

How many main stem villi are contained within the placenta?

18
Q

At term, what is the only layer of the placenta which separates the endothelium of the villous capillaries from the maternal circulation?

A

Syncitiotrophoblasy

19
Q

The spiral arteries are remodelled from low flow high resistance to high flow low resistance during development of the placenta. T/F?

20
Q

Which vessel(s) carries deoxygeneated blood from the foetus?

A

Umbilical arteries

21
Q

Which vessel(s) carries oxygenated blood to the foetus fo the placenta?

A

Umbilical vein

22
Q

What vessels transport maternal blood to and from the placenta?

A

Uterine arteries supply placenta with oxygenated blood

Uterine veins drain deoxygenated blood from the placenta

23
Q

What substances diffuse or are transported from maternal to foetal blood?

A
Oxygen
Glucose
Fatty acids
Ionic substances
Antibodies
24
Q

In the placenta, glucose undergoes facilitated diffusion via which transporter to reaCh the foetal blood?

A

Hexose transporter

25
What is the barker hypothesis?
The hypothesis which states that babies which are too small at borth are predisposed to adult diseases
26
Preecmapsia is a disorder of late pregnancy. What blood pressure and level of proteinuria are diagnostic of preeeclampsia?
Bp over 140/90 mmHg | Proteinuria over 300mg in 24hours
27
What happens to cause preeclampsia?
There is invasion of trophoblasts into the maternal tissue and the spinal arteries do not undergo physiological change and blood flow to the placenta is reduced
28
What adult conditions are linked to low birth weight?
Obesity | Cardiovascular disease