Plaquetas, Coagulación, Fibrinólisis y Anticoagulantes Flashcards

1
Q

Cuales son las 2 principales proteínas asociadas a la activación de la fibrinólisis

A

Activador de plasminogeno tisular (TPA)
Uroquinasa (UPA)

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2
Q

Esta proteína es familia de la proteasa de serina y digiere la fibrina?

A

Plasminogeno

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3
Q

Que activa el activador del plasminogeno tisular?

A

Endotelio

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4
Q

Esta proteína activa el plasminogeno y es secretada por el riñon?

A

Uroquinasa

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5
Q

Inhibe a la Plasmina

A

a2- antiplasmina

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6
Q

Si la proteína C no funciona, se provoca un estado:

A

procoagulante

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7
Q

Inhiben la fibrinolisis uniéndose a los sitios de uno de TPA y plasminogeno

A

Medicamentos análogos de la lisisma.

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8
Q

La heparina se produce en

A

Células endoteliales y mastocitos

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9
Q

La heparina degrada

A

Factor X

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10
Q

F. Inhibidor de las proteasas coagulantes

A

Heparina

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11
Q

F. Bloquean multiples fases de coagulación (principalmente de vit k)

A

Cumarínicos (Warfina)

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12
Q

F. Degradan trombos

A

Fibrinolíticos (Estreptoquinasa y Uroquinasa)

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13
Q

F. Inhibe al factor II

A

Dabigratan

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