Plasma Enzymes Flashcards
(33 cards)
Inherited abnormal variants of plasma cholinesterase with low biological activity
Decreased plasma cholinesterase
Hepatic disease
Decreased plasma cholinesterase synthesis
Ingestion of organophosphates or absorption via skin
Decreased cholinesterase activity (acts as irreversible inhibitor)
High levels of acetylcholine
Decreased plasma cholinesterase
Atropine sulfate
Decreased plasma cholinesterase (competitive antagonist)
Nephrotic syndrome
Increased plasma cholinesterase (excreted in urine)
Rapidly growing cells: liver recovery
Increased plasma cholinesterase
AST is normally high in what cells?
Cardiac and skeletal muscle, liver, kidney, erythrocytes
Artefactual (hemolysis) causes?
High AST
Myocardial infarction causes?
Very High AST
Circulatory failure causes?
Very High AST and Marked increases of ALT
Acute viral hepatitis causes?
Very High AST and Marked increases of ALT
Cells that have high concentrations of ALT?
Liver, skeletal muscle, kidney (lesser extent)
Liver cirrhosis causes?
Moderate increases of ALT
Cholestatic jaundice causes?
Moderate increases of ALT
Post cardiac surgery causes?
Moderate increases of ALT
Skeletal muscle disease causes?
Moderate increases of ALT
Pregnancy
Changes in ALP
Infancy and childhood causes?
Changes in ALP
High fat meals cause?
Changes in ALP
Diseases that affect the bile duct cause?
Changes in ALP
Bone diseases cause?
Changes in ALP
What cells acid acid phosphatase found in?
Prostate, liver, erythrocytes, platelets, bone
Which type of lactate dehydrogenase is indicative of myocardial infarction?
High LDH-1
