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Plasma Membrane Flashcards

(17 cards)

0
Q

PM has NO _______________ bonds

A

NO TRANS DOUBLE BONDS IN PM

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1
Q

PM composed of

A

Lipids
Sterols
Proteins

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2
Q

PM functionality based on

A

Length and saturation of fatty acid

Hydrophilic head group composition

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3
Q

Phosphoglycerides

A

Glycerol (3C) base w 2 fatty acid chains
Common= both linked via ester
Plasmogen= 1 linked via ester linkage to glycerol
3rdC of glycerol= polar head group

Variable head group
PE-NH3
PC-NCH3
PS-carboxyl
PI- ring
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4
Q

Sphingolipids

A

Base= sphingosine - amino alcohol w 1 fatty acid gain
Link additional fatty acid chain via amide bond

Glycolipid= sugar head group

Variable head groups
SM-NCH3
GlcCer- ring

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5
Q

Sterol

A

4 ring hydrocarbon
Cholesterol
Intercalate between phospholipids and align polar group with polar head
Lipid composition can affect thickness and curvature of PM

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6
Q

Phospholipids can be what type if membrane lipids?

A

Phosphoglycerides or sphingolipids

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7
Q

Properties of bio membranes

A

Fluid
Closed compartments
Semi-permeable
Asymmetric

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8
Q

FRAP assay

A

Fluorescence recovery after photo bleaching assay

  1. Label membrane proteins w fluorescent reagent
  2. Bleach portion w laser
  3. At a later time pt, measure amount of fluorescence recovered in that area

%fluorescence recovered proportional to fluidity

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9
Q

Carbohydrates on what leaflet of PM?

A

Exoplasmic

Not cytosolic
Therefore, asymmetry

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10
Q

Passive diffusion does not require

A

A transmembrane protein

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11
Q
Primary Active transport 
P class pumps pump
A

H+
K+
Na+
Ca2+

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12
Q
Primary Active transport 
V and F class pumps pump
A

H+ only

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13
Q

Primary Active transport

ABC type pumps pump

A

Many small molecules

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14
Q

Secondary active transport

A

No E required

Requires primary active transport, uses conc gradient created by it

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15
Q

Voltage gates channel

A

Change in membrane potential opens channel
E.g. Ca2+ release channel on sarcoplasmic reticulum

Facilitated transport (driven by conc gradient)
Gates
16
Q

Facilitated transport-types

A

Pores
Channels
Gates
Uniporters