Platelet And Coagulation Flashcards
(35 cards)
Describe cat platelets
Clump easily, vary in size
Describe platelets of dogs (general)
Small, round - oval, 3 microns, light blue, purple or pink granules
Describe horses platelets
They don’t stain very well
Describe cows platelets
Small, oval - round, 3 microns, light blue, purple or pink granules
Describe llamas platelets
Very small
How can clumps affect automated analyzers?
False low count
How many platelets /hpf is normal?
8-10
How do you estimate platelets numbers from how many you see /hpf?
Multiply average of 10 fields
x
20,000
How can you minimize platelets clumping?
Draw from large vessel, 18-22g needle, anticoagulant ASAP, make slide ASAP
Platelet clumping often affects which species?
Cats
What are the normal platelets counts /uL for cats?
160,000-700,000
What are the normal platelets counts /uL for dogs?
160,000-625,000
Platelet counts under
1,000,000/uL
Thrombocytopenia
Platelet counts under 20,000-50,000/uL
Results in spontaneous bleeding
Platelet counts over 1,000,000
Thrombocytosis or thrombocythemia
What does MPV measure?
Average platelet size
What does PDW measure?
Variation in size
Hemostasis
Maintain integrity of blood and blood vessels
3 stages of hemostasis
Primary, secondary, tertiary
What 3 things are involved in the primary stage?
Vessel wall, platelets, VWB factor
What 3 actions do platelets make?
Adhesion, activation, aggregation
Where are most proteins produced?
Liver
What happens during tertiary hemostasis?
Plasmin
What is the most common inherited disease of hemostasis in dogs?
vWb disease