Pleh Flashcards

(30 cards)

1
Q

What’s the order of spermatogenesis?

A

Spermatogonia
Primary spermatocyte
Secondary spermatocyte
Soermatids
Spermatozoa

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2
Q

What’s the order of oogenesis?

A

Oogonia
Primary oocyte
Large primary oocyte
Secondary oocyte
Ovum

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3
Q

Where do primordial germ cells originate?

A

Extra embryonic tissue

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4
Q

How do primordial germ cells migrate into the embryo?

A

Via the gut and into the genital ridge, multiplying as they go

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5
Q
A
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6
Q

What does the genital ridge give rise to?

A

Somatic cells of the gonad

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7
Q

What do the primordial germ cells do once they reach the genital ridge?

A

Meiosis to produce gametes

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8
Q

How are spermatogonia produced?

A

PGCs multiply during migration

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9
Q

When are spermatogonia arrested?

A

G1

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10
Q

How are spermatocytes produced?

A

After birth and in adults, diploid spermatogonia undergo mitosis to generate spermatocytes

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11
Q

How are spermatids formed?

A

Spermatocytes undergo meiosis to produce haploid spermatids. Incomplete cytokinesis forms syncytia

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12
Q

What produces spermatozoa?

A

Spermatids differentiation

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13
Q

What do the carbohydrate lytic enzymes digest?

A

Beta-N-acetylglucosaminidase

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14
Q

What’s the arrangement of microtubules in the axoneme?

A

2 central singlet surrounded by 9 doublet microtubules

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15
Q

What’s the function of Dynein?

A

Use energy from ATP hydrolysis to slide microtubules in axoneme past one another

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16
Q

What’s the difference in meiosis between spermatogenesis and oogenesis?

A

Spermatogenesis: meiosis before differentiation
Oogenesis: meiosis after differentiation

16
Q

How are oogonia generated?

A

PGCs multiply during migration to generate diploid oogonia

18
Q

How are primary oocytes generated?

A

Diploid oogonia enter meiosis and arrest in prophase 1 as primary oocytes

19
Q

When do primary oocytes start to mature?

A

In adults, after puberty

20
Q

When does meiosis 1 complete in oogenesis?

A

Complete just before ovulation

21
Q

What condition must be met for secondary oocytes to finish metaphase II?

A

Fertilisation

22
Q

When is the first polar body produced in oogenesis?

A

When Primary oocyte completes meiosis 1 just before ovulation

23
Q

When is the second polar body produced in oogenesis?

A

After fertilisation when meiosis 2 is completed

24
What’s the function of beta-N-acetylglucosaminidase?
Digests N-acetylglucosamine residues from O-linked oligosaccharides on ZP3
25
What’s the function of acrosin
Serine protease which lyses the Zona pellucida
26
Function of CD9?
Facilitates structural changes for cytoplasmic fusion
27
How does the Ca2+ influx cause the completion of meiosis II?
Ca2+ activates a kinase that leads to proteolysis of cyclin
28
What did Driesch do?
Removed early embryo cells from sea urchins to show pre formation isn’t true and that cells retain developmental flexibility
29
What did Wolff do?
Observed progressive tissue growth and differentiation in chick embryos to disprove pre formation