Plural Effusions Flashcards

(44 cards)

1
Q

What does plural effusions result from

A

Imbalance between fluid formation and resorption within the plural space

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2
Q

symptoms of Plural effusions

A

dyspnea, trepopnea, orthopnea, cough, or chest pain

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3
Q

plural effusions imaging studies

A

chest radiographs, computed tomography [CT], ultrasonography and analyses of pleural fluid

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4
Q

physical examination are suggestive of pleural effusion

A

decreased breath sound with dullness on percussion

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5
Q

what is performed in the assessment of pleural effusion

A

Posteroanterior chest radiography

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6
Q

how do Pleural effusions ≥200 mL normally exhibit on chest radiographs

A

an abnormal opacity with decreased lung volume

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7
Q

what can effusions of as little as 50 mL cause on chest radiographs

A

blunting of the costophrenic angle

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8
Q

what is gold standard investigation to diagnose a pleural effusion

A

ultrasonography

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9
Q

what can Ultrasonography detect within the pleural space with greater sensitivity than CT

A

fibrin and septations

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10
Q

when can ultrasonography be used to minimizing procedure-related complications and increases the success rate

A

during thoracentesis

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11
Q

when is Chest CT with contrast is useful

A

for the evaluation of exudative pleural effusions

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12
Q

critical findings of Chest CT with contrast

A

malignant effusion, mesothelioma, complications of lung infection (parapneumonic effusion, empyema), and vascular or lymphatic obstruction

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13
Q

what is critical in characterizing the type of pleural effusion

A

Pleural fluid analysis

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14
Q

Pleural effusion may appear as

A

serous, serosanguinous, bloody, purulent, or milky

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15
Q

when is putrid purulent fluid seen

A

anaerobic empyema

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16
Q

when is milky fluid seen

A

chylothorax or pseudochylothorax

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17
Q

when is bile-stained fluid seen

A

biliary-pleural fistula

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18
Q

what are the Results of pleural fluid analysis are used for

A

categorize pleural effusion as transudative and exudative using Light’s criteria

19
Q

Light’s criteria

A

are highly sensitive for an exudative process (sensitivity, 98%; specificity, 83%)

20
Q

what are Pleural fluid differential cell counts helpful in

A

the differential diagnosis but not disease-specific

21
Q

Neutrophil predominance in Pleural fluid differential cell counts

A

– Parapneumonic effusion
– Pulmonary embolism
– Early tuberculous pleuritis
– Benign asbestos pleural effusion

22
Q

Lymphocyte predominance in Pleural fluid differential cell counts

A
– Malignancy
– Tuberculous pleuritis
– Lymphoma
– Cardiac failure
– After coronary bypass graft
– Rheumatoid effusion
– Chylothorax
– Uremic pleuritis
– Sarcoidosis
– Yellow nail syndrome
– Pulmonary embolism
23
Q
Eosinophilia (≥10% of nucleated cells) in Pleural fluid differential cell counts  
#Pleural eosinophilia is a relatively nonspecific finding.#
A
– Parapneumonic effusion
– Drug-induced pleuritis
– Benign asbestos pleural effusion
– Eosinophilic granulomatosis with polyangiitis
– Lymphoma
– Pulmonary embolism
– Parasitic infestation
– Malignancy
24
Q

what is Chylothorax

A

pleural effusion caused by the leakage of lymphatic fluid into the pleural space from a ruptured thoracic duct or obstruction of the lymphatic vessels.

25
what causes Chylothorax
Malignancy (most commonly lymphoma or metastases of other cancers); injury, including surgery (particularly of the esophagus), chest trauma, sometimes catheterization of the superior vena cava; lymphangioleiomyomatosis; obstruction of a vena cava; amyloidosis
26
on what basis is Chylothorax Diagnosis made
pleural fluid analysis
27
Chylothorax appearance
The fluid is milky-white and odorless and contains chylomicrons
28
Chylothorax level of triglycerides is
>1.24 mmol/L (110 mg/dL)
29
Chylothorax level of cholesterol is
<2.59 mmol/L (100 mg/dL).
30
does Chylothorax contain cholesterol crystals
no
31
Chylothorax has to be differentiated from
pseudochylothorax
32
what causes pseudochylothorax
it occurs very rarely and is a result of the accumulation of cholesterol in a chronic pleural effusion
33
examples of chronic pleural effusion that causes pseudochylothorax
tuberculosis or rheumatoid arthritis
34
pseudochylothorax appearance
has the same appearance as in chylothorax
35
pseudochylothorax level of cholesterol is
>5.18 mmol/L (200 mg/dL)
36
pseudochylothorax level of triglycerides is
<0.56 mmol/L (50 mg/dL).
37
does pseudochylothorax contain cholesterol crystals
yes
38
Treatment of chylothorax and pseudochylothorax
pleural drainage and management of the underlying disturbances
39
what diet is recommended for chylothorax
high-protein low-fat (<10 g/d) diet
40
why is Total parenteral nutrition used for chylothorax
to reduce lymph production
41
what is done when oral therapy is insufficient for chylothorax
close the fistula between the lymph vessel and the pleural space
42
adjunctive therapies for chylothorax
Somatostatin and octreotide
43
In two-thirds of patients chylothorax resolves after
12 to 14 days
44
what is is an indication for surgical treatment
A constant lymph outflow >500 mL/d