PME 2 Drugs Flashcards

(130 cards)

1
Q

Sodium chloride 0.9% Indications

A
  • Inadequate tissue perfusion/ shock
  • Hypovolaemia
  • Significant burns >20% adult >10% Paed
  • To dissolve and dilute drugs
  • As a flush for IV or IO drug administration
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2
Q

Sodium chloride 0.9% Contraindications

A

Nil

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3
Q

Sodium chloride 0.9% Presentations

A
  • Ampule, 10 mL
  • Bag, 100 mL
  • Bag, 500 mL
  • 10 mL pre-filled syringe
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4
Q

Salbutamol Indications

A
  • Bronchospasm
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5
Q

Salbutamol Contraindications

A
  • Allergy
  • Pt < 1 year of age
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6
Q

Salbutamol Presentations

A
  • MDI, 100 microg / puff
  • Nebule, 2.5 mg / 2.5 mL
  • Nebule, 5 mg / 2.5 mL
  • Ampule, 500 microg / 1 mL
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7
Q

Salbutamol MDI dose - Bronchospasm (ADULT)

A

12 (1.2 mg) puffs
Repeated every 10 mins
No max dose

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8
Q

Salbutamol NEB dose - Bronchospasm (ADULT)

A

5 mg
Repeated PRN
No max dose

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9
Q

Salbutamol MDI dose - Bronchospasm (PAED 1-5 years)

A

6 (600 microg) puffs
Repeated every 10 mins
No max dose

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10
Q

Salbutamol MDI dose - Bronchospasm (PAED > 6 years)

A

12 (1.2 mg) puffs
Repeated every 10 mins
No max dose

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11
Q

Salbutamol NEB dose - Bronchospasm (PAED 1-5 years)

A

2.5 mg
Repeated PRN
No max dose

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12
Q

Salbutamol NEB dose - Bronchospasm (PAED > 6 years)

A

5 mg
Repeated PRN
No max dose

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13
Q

Ipratropium bromide indications

A
  • Moderate bronchospasm (unresponsive to initial QAS salbutamol NEB)
  • Severe bronchospasm
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14
Q

Ipratropium bromide contraindications

A
  • Allergy
  • Pt < 1 year
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15
Q

Ipratropium bromide presentation

A

Nebule, 250 microg / 1 mL

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16
Q

Ipratropium bromide NEB dose - Moderate bronchospasm (ADULT)

A

500 microg
Repeated at 20 min intervals
1.5 mg total MAX dose

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17
Q

Ipratropium bromide NEB dose - Severe bronchospasm (ADULT)

A

500 microg
Repeated at 20 min intervals
1.5 mg total MAX dose

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18
Q

Ipratropium bromide NEB dose - Moderate bronchospasm (PAED 1-5 years)

A

250 microg
Repeated at 20 min intervals
750 microg total MAX dose

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19
Q

Ipratropium bromide NEB dose - Severe bronchospasm (PAED 1-5 years)

A

250 microg
Repeated at 20 min intervals
750 microg total MAX dose

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20
Q

Ipratropium bromide NEB dose - Moderate bronchospasm (PAED >6 years)

A

500 microg
Repeated at 20 min intervals
1.5 mg total MAX dose

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21
Q

Ipratropium bromide NEB dose - Severe bronchospasm (PAED >6 years)

A

500 microg
Repeated at 20 min intervals
1.5 mg total MAX dose

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22
Q

Paracetamol indications

A
  • Mild to moderate pain
  • Fever causing distress
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23
Q

Paracetamol contraindications

A
  • Allergy
  • Pt < 1 month of age
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24
Q

Paracetamol presentation

A
  • Tablet, 500 mg
  • Elixir, 120 mg / 5 mL
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25
Paracetamol PO dose - Mild to moderate pain (ADULT)
0.5 - 1 g Repeated every 4 hours 4 g max dose in 24 hours
26
Paracetamol PO dose - Fever causing distress (ADULT)
0.5 - 1 g Repeated every 4 hours 4 g max dose in 24 hours
27
Paracetamol PO dose - Fever causing distress (PAED > 1 month of age)
15 mg / kg Single max dose of 1 g Not to be administered with in 4 hours of previous paracetamol administration
28
Paracetamol PO dose - Mild to moderate pain (PAED > 1 month of age)
15 mg / kg Single max dose of 1 g Not to be administered within 4 hours of previous paracetamol administration
29
What is the formula for drug calculations
Dose x Volume / Stock strength
30
Ibuprofen indications
Moderate pain due to acute inflammation and tissue injury
31
Ibuprofen contraindications
- Allergy to any NSAID or aspirin - Concurrent NSAID treatment - Current GI bleed to peptic ulcers - Dehydration and/ or hypovolamemia - Renal impairment - NSAID induced asthma - Heart failure - Pregnancy - ACE or ARB treatment - Pt < 13 years - Pt taking anticoagulant medications - Diuretic treatment
32
Ibuprofen presentation
Tablet, 200 mg
33
Ibuprofen PO dose - Moderate pain due to acute inflammation and tissue injury
200 - 400 mg Must not be administered within 6 hours of previous dose
34
Ibuprofen PO dose (PEAD)
Ibuprofen is not indicated for paediatric patients
35
Methoyflurane indications
Pain
36
Methoxyflurane contraindications
- Allergy - Pts < 1 year - Hx of significant liver or renal disease - Hx of malignant hyperthermia
37
Methoxyflurane presentation
Bottle, 3 mL
38
Methoxyflurane INH dose - Pain (ADULT)
3 mL Repeat after 20 mins 6 mL total max dose
39
Methoxyflurane INH dose - Pain (PAED > 1 year)
3 mL Single dose only
40
Morphine indications
- Significant pain - Sedation - Autonomic dysreflexia
41
Morphine contraindications
- Allergy - Kidney disease (renal failure)
42
Morphine presentation
Ampule, 10 mg / 1 mL
43
Morphine IM dose - Significant pain & Autonomic Dysreflexia (ADULT > 70 years)
2.5 - 5 mg Repeated at up to 5 mg every 10 mins 10 mg total max dose
44
Morphine IM dose - Significant pain & Autonomic Dysreflexia (ADULT < 70 years)
2.5 - 5 mg Repeated at up to 5 mg every 10 mins 20 mg total max dose
45
Morphine IV dose - Significant pain & Autonomic Dysreflexia (ADULT < 70 years)
2.5 - 5 mg Repeated at up to 5 mg every 10 mins 20 mg total max dose
46
Morphine IV dose - Significant pain & Autonomic Dysreflexia (ADULT > 70 years)
2.5 - 5 mg Repeated at up to 5 mg every 10 mins 10 mg total max dose
47
Morphine IM dose - Significant pain & Autonomic Dysreflexia (PAED > 1 year)
100-200 microg / kg Single max dose 5 mg Total max dose 200 microg / kg
48
Morphine IV dose - Significant pain & Autonomic Dysreflexia (PAED > 1 year)
100 microg / kg Single max dose 2.5 mg Total max dose 200 microg / kg
49
Ondensetron indications
Significant neausa and/ or vomiting
50
Ondansetron contraindications
ABSOLUTE - Allergy - Congenital long QT syndrome - Apomorphine treatment - Pt < 2 years RELATIVE - First trimester pregnancy
51
Ondansetron presentation
- Ampule, 4 mg / 2 mL - ODT, 4 mg
52
Ondansetron IM dose - Significant nausea/ vomiting (ADULT)
4-8 mg 8 mg total max dose Not to be given within 8 hours of previous dose
53
Ondansetron PO dose - Significant nausea/ vomiting (ADULT)
4-8 mg 8 mg total max dose Not to be given within 8 hours of previous dose
54
Ondansetron IV dose - Significant nausea/ vomiting (ADULT)
4-8 mg Slow push over 2 - 3 mins 8 mg total max dose Not to be given within 8 hours of previous dose
55
Ondansetron PO dose - Significant nausea/ vomiting (PAED 2-4 years)
2 mg Single dose only
56
Ondansetron PO dose - Significant nausea/ vomiting (PAED > 5 years)
4 mg Single dose only
57
Ondansetron IM dose - Significant nausea/ vomiting (PAED > 2 years)
100 microg / kg (rounded to nearest 5 kg) Single dose only 4 mg total max dose
58
Ondansetron IV dose - Significant nausea/ vomiting (PAED > 2 years)
100 microg / kg Single dose only 4 mg total max dose
59
Hydrocortisone indications
- Asthma (excluding mild) - Acute exacerbation of COPD with signs of respiratory distress - Refractory Anaphylaxis with persistent wheeze (refractory to 3 x IM adrenaline) - Suspected or at risk of acute adrenal insufficiency
60
Hydrocortisone contra indications
Allergy
61
Hydrocortisone presentation
Vial (powder or powder and solvent), 100 mg
62
Hydrocortisone preparation
Each 100 mg vial is to be reconstituted with 2 mL of water for injection
63
Hydrocortisone IM dose - Asthma, acute exacerbation of COPD & adrenal crisis (ADULT)
100 mg Single dose only
64
Hydrocortisone IV dose - Asthma, acute exacerbation of COPD & adrenal crisis (ADULT)
100 mg Slow push over 1 min Single dose only
65
Hydrocortisone IM dose - Refractory anaphylaxis (ADULT)
200 mg Single dose only
66
Hydrocortisone IV dose - Refractory anaphylaxis (ADULT)
200 mg Slow push over 1 min Single dose only
67
Hydrocortisone IV dose - Asthma & Refractory anaphylaxis (PAED)
4 mg / kg Not to exceed 100 mg Single dose only
68
Hydrocortisone IV dose - Asthma & Refractory anaphylaxis (PAED)
4 mg / kg Not to exceed 100 mg Slow push over 1 min Single dose only
69
Hydrocortisone IM dose - Adrenal crisis (PAED 0 - 4 years)
25 mg Single dose only
70
Hydrocortisone IM dose - Adrenal crisis (PAED 5 - 10 years)
50 mg Single dose only
71
Hydrocortisone IM dose - Adrenal crisis (PAED > 10 years)
100 mg Single dose only
72
Hydrocortisone IV dose - Adrenal crisis (PAED 0 - 4 years)
25 mg Slow push over 1 min Single dose only
73
Hydrocortisone IV dose - Adrenal crisis (PAED 5 - 10 years)
50 mg Slow push over 1 min Single dose only
74
Hydrocortisone IV dose - Adrenal crisis (PAED > 10 years)
100 mg Slow push over 1 min Single dose only
75
Fentanyl indications
- Significant pain - Autonomic dysreflexia with systolic BP > 160 mmHg
76
Fentanyl contraindications
Allergy
77
Fentanyl presentation
Ampule, 100 microg / 2 mL
78
Fentanyl NAS dose - Significant pain & Autonomic dysreflexia systolic BP > 160 mmHg (ADULT > 70 years)
25 - 50 microg Repeated at up to 50 microg every 10 mins 100 microg total max dose
79
Fentanyl NAS dose - Significant pain & Autonomic dysreflexia systolic BP > 160 mmHg (ADULT < 70 years)
50 - 100 microg Repeated at up to 100 microg every 10 mins 200 microg total max dose
80
Fentanyl IM dose - Significant pain & Autonomic dysreflexia systolic BP > 160 mmHg (ADULT > 70 years)
25 - 50 microg Repeated at up to 50 microg every 10 mins 100 microg total max dose
81
Fentanyl IM dose - Significant pain & Autonomic dysreflexia systolic BP > 160 mmHg (ADULT > 70 years)
50 - 100 microg Repeated at up to 100 microg every 10 mins 200 microg total max dose
82
Fentanyl IV dose - Significant pain & Autonomic dysreflexia systolic BP > 160 mmHg (ADULT > 70 years)
25 microg Repeated at up to 25 microg every 10 mins 100 microg total max dose
83
Fentanyl IV dose - Significant pain & Autonomic dysreflexia systolic BP > 160 mmHg (ADULT > 70 years)
25 - 50 microg Repeated at up to 50 microg every 10 mins 200 microg total max dose
84
Fentanyl NAS dose - Significant pain (PAED > 1 year)
1.5 microg / kg Single max dose of 50 microg Repeated at 1 microg / kg at 10 mins 100 microg total max dose
85
Fentanyl IM dose - Significant pain (PAED > 1 year)
1 - 2 microg / kg Single max dose of 50 microg 2 microg / kg total max dose
86
Fentanyl IV dose - Significant pain (PAED > 1 year)
1 microg / kg Single max dose of 25 microg Repeated at 0.5 microg / kg (max 25 microg) at 5 mins 2 microg / kg total max dose of
87
Midazolam indications
- Generalised seizures / Focal seizure (GSC < 12) - Acute behavioural disturbances ( SAT score ≧ 2 )
88
Midazolam contraindications
Allergy
89
Midazolam presentation
Ampule, 5 mg / 1 mL
90
Midazolam NAS dose - Generalised/ focal seizure (ADULT)
5 mg Repeated every 5 mins 20mg total max dose
91
Midazolam IM dose - Generalised/ focal seizure (ADULT)
5 mg Repeated every 5 mins 20mg total max dose
92
Midazolam IV dose - Generalised/ focal seizure (ADULT)
5 mg Repeated every 5 mins 20mg total max dose
93
Midazolam NAS dose - Generalised/ focal seizure (PAED)
Refer to QAS DTP
94
Midazolam IM dose - Generalised/ focal seizure (PAED)
Refer to QAS DTP
95
Glyceryl trinitrate ( GTN ) indications
- Suspected ACS with pain - Acute cardiogenic pulmonary oedema - Autonomic dysreflexia ( SYS BP > 160 mmHg ) - Irukandji syndrome ( SYS BP > 160 mmHg )
96
Glyceryl trinitrate ( GTN ) contrindications
- Allergy - HR < 50 or > 150 BPM - SYS BP < 100 mmHg - Acute CVA - Head trauma - Viagra type drugs in the pas 48 hours
97
Glyceryl trinitrate ( GTN ) presentation
- Spray, 400 microg / dose - Ambule, 50 mg / 10 mL
98
Glyceryl trinitrate ( GTN ) dose (ADULT)
400 microg Repeated every 5 mins NO max dose
99
Glyceryl trinitrate ( GTN ) dose (PAED)
QAS Clinical consult for approval
100
Glucagon indications
- Symptomatic hypoglycaemia (with inability to self administer oral glucose) - Refractory Anaphylaxis with persistent hypotension/ shock (Unresponsive to 3 x IM adrenaline injections and adequate fluid challenges)
101
Glucagon contraindications
Allergy
102
Glucagon presentation
Vial (powder & solvent), 1 mg of glucagon
103
Glucagon IM dose - Symptomatic hypoglycaemia (ADULT)
1 mg Single dose only
104
Glucagon IV dose - Refractory anaphylaxis (ADULT)
1 mg Single dose only
105
Glucagon IM dose - Symptomatic hypoglycaemia (PAED)
> 25 kg 1 mg Single dose only ≦ 25 kg 0.5 mg Single dose only
106
Glucagon IM dose - Refractory anaphylaxis (PAED)
> 25 kg 1 mg Single dose only ≦ 25 kg 0.5 mg Single dose only
107
Glucagon IV dose - Refractory anaphylaxis (PAED)
> 25 kg 1 mg Single dose only ≦ 25 kg 0.5 mg Single dose only
108
Adrenaline indications
- Cardiac arrest - Anaphylaxis OR severe allergic reaction - Severe life-threatening bronchospasm OR silent chest - Shock unresponsive to adequate fluid resuscitation (CCP) - Bradycardia (unresponsive to atropine AND/ OR transcutaneous pacing) (CCP) - Croup (moderate to severe)
109
Adrenaline contraindications
NIL
110
Adrenaline presentation
- Ampule, 1 mg/ 1 mL (1:1,000) - Ampule, 1 mg/ 10 mL (1:10,000) - EpiPen, 300 microg auto-injector - EpiPen Jr 150 microg auto-injector
111
Adrenaline IV dose - Cardiac arrest (ADULT)
1 mg Repeat every 3 - 5 mins NO max dose
112
Adrenaline IM does - Anaphylaxis OR severe allergic reaction (ADULT)
500 microg Repeat every 5 mins NO max dose
113
Adrenaline NEB dose - Anaphylaxis OR severe allergic reaction (ADULT)
FOR UPPER AIRWAY OBSTRUCTION 5 mg Single dose only Refractory to 3 x IM adrenaline injections
114
Adrenaline IM dose - Severe life-threatening bronchospasm or silent chest (ADULT)
500 microg Repeat every 5 mins NO max dose
115
Adrenaline IV dose - Cardiac arrest (PAED)
10 kg or more (> 1 year) - 10 microg / kg Repeat every 3-5 mins NO max dose Less then 10 kg (excluding newly born) - 100 microg Repeated every 3-5 mins NO max dose Newly born - 50 microg Repeated every 3-5 mins NO max dose
116
Adrenaline IM dose - Anaphylaxis OR severe allergic reaction (PAED)
6 years or older - 300 microg Repeated every 5 mins NO max dose 1 to 6 years - 150 microg Repeated every 5 mins NO max dose 6 months to 1 year - 100 microg Repeated every 5 mins NO max dose Less than 6 months - 50 microg Repeated every 5 mins NO max dose
117
Adrenaline NEB dose - Anaphylaxis OR severe allergic reaction (PAED)
5 mg Single dose only May be administered for upper airway obstruction that is refractory to 3 x IM adrenaline injections
118
Adrenaline IM dose - Severe life-threatening bronchospasm OR silent chest (PAED)
6 years or older - 300 microg Repeated every 5 mins NO max dose 1 to 6 years - 150 microg Repeated every 5 mins NO max dose 6 months to 1 year - 100 microg Repeated every 5 mins NO max dose Less than 6 months - 50 microg Repeated every 5 mins NO max dose
119
Adrenaline NEB dose - Croup (PAED)
5 mg Single dose only
120
Amiodarone indications
Cardiac arrest refractory to 3 x DCCS
121
Amiodarone contraindications
Tricyclic antidepressant overdose
122
Amiodarone presentation
Ampule, 150 mg/ 3 mL
123
Amiodarone IV dose - Cardiac arrest Refractory to 3 x DCCS
300 mg first dose Slow push over 1-2 mins 150 mg second dose refractory to 5 x DCCS 450 mg total max dose
124
Ceftriaxone indications
Suspected meningococcal septicaemia
125
Ceftriaxone contraindications
ABSOLUTE Allergy Known immediate OR severe hypersensitivity to penicillin OR carbapenem base drugs RELATIVE PT < 1 month of age (QAS Clinical consult required)
126
Ceftraxone presentation
Vial (powder), 1 g
127
Ceftriaxone IM dose - Meningococcal septicaemia (ADULT)
2 g Single dose only
128
Ceftriaxone IV dose - Meningococcal septicaemia (ADULT)
2 g Single dose only Slow push over 5 mins
129
Ceftriaxone IM dose - Meningococcal septicaemia (PAED)
50 mg/ kg rounded to the nearest 5 kg 1 g total max dose Single dose only ≦ 5 kg - 250 mg > 5 - 10 kg - 500 mg > 10 - 15 kg - 750 mg > 15 kg - 1 g
130
Ceftriaxone IV dose - Meningococcal septicaemia (PAED)
Greater than 20 kg 50 mg/ kg rounded to the nearest 5 kg Slow push over 5 mins 2 g total max dose Single dose only > 20 - 25 kg - 1.25 g > 25 - 30 kg - 1.5 g > 30 - 35 kg - 1.75 g > 35 kg - 2 g