Pneumonia Drugs

Question 1

Outpt uncomplicated TXT

Answer 1

1. Macrolide or FQ

2. Tetracycline

Question 2

Outpt TXT w/ comorbids (No HCAP)

Answer 2

1. FQ

2. Beta-lactamase inhib + Macrolide

Question 3

Macrolide

Answer 3

(azithro/clarithro)

Question 4

Tetracycline

Answer 4

(Doxy)

Question 5

FQ

Answer 5

(New - Levoflox, Moxiflox, gemiflox)

Other - cipro)

Question 6

Beta-lactamase inhib

Answer 6

Amoxicillin-Clav
ampicillin/sulbactam
Piperacillin-tazobactam

Question 7

Inpt Non-ICU w/ CAP

Answer 7

1. FQ

2. Ceph or PCN (Beta inhib) + macrolide

Question 8

Empiric - pts w/ suspected HCAP (3 drug)

Answer 8

1. Antipseudomonal cephalosporin
   + FQ + MRSA (vancomycin)
2. Antipseudomonal carbapenem
   + FQ + MRSA (Vancomyin)
3. B-lactamase inhibitor
   + Antipseudomonal fluoroquinolone + MRSA (Vanc)

Question 9

Antipseudomonal cephalosporin

Answer 9

Cefepime

Ceftazidime

Question 10

Antipseudomonal carbapenem

Answer 10

Imipenem

Meropenem

Question 11

Inpt ICU

Answer 11

1. Ceph + Macrolide
2. Ceph + FQ
3. FQ + Monobactam OR lincosamide
   (Add Vanc or Linezolid if HCAP/MRSA)

Question 12

Inpt Psuedomonas risk

Answer 12

1. B-lactamase inhibitor + FQ
2 cefepime + FQ
ALT- carbapenem + FQ OR aminoglycoside
PCN allergy- Monobactam + FQ
(Add Vanc or Linezolid HCAP/MRSA)

Question 13

Eryhtromycin notes

Answer 13

Cheap, for CAP
GI SE
Photosensitivity

Question 14

Clarithromycin notes

Answer 14

fewer GI SE

Metallic taste

Question 15

Azithromycin

Answer 15

once-a-day or single-dose therapy

Question 16

New FQs

Answer 16

extend coverage to common and atypical agents + once-a-day dosing

Question 17

FQs are for

Answer 17

pts cant tolerate other agents,
documented pneumococcal resistance,
or failed other therapies

Question 18

CI for FQ

Answer 18

myasthenia gravis

Question 19

Broad Spec ABX increases risk for what?

Answer 19

Bacterial resistance if given w/in last 3 mo

Question 20

ICU pt - PCN-allergy

Answer 20

FQ + aztreonam OR clindamycin