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Flashcards in PNS Deck (11):
1

ANS

2 neurones outside CNS
- preganglionic (myelinated B fibres) arising from CNS
- postganglionic (non-myelinated C fibres) in ganglia

2

PNS output

Mid-brain, medulla leaving with cranial nerves + sacral part of SC. Parasympathetic ganglia - near to/ in innervated tissues

3

SNS output

T1-12, L1-3

4

ACh released from all ------ of ------- and -------

Preganglionic neurones, bot parasympathetic and sympathetic nerves + from postganglionic parasympathetic nerves

5

Most postganglionic sympathetic neurons release except

NA
cholinergic postganglionic sympatheric neurons in sweat glands of skin, adrenal medullary cells - N1

6

Pre: post ganglionic ration in sympathetically innervated organs and parasympathetically innverated organs excluding the gut

1: 20, 1:1

7

Co-transmission in ganglia

Slow excitatory effect - reduction in K+ permeability/ inhibitory effect

8

Examples of classical NANC's

DA, GABA, 5-HT

9

Puriergic transmission

NANC - ATP as transmitter Fast EPSP -> P1 or P2

10

Peptide transmitters

BIP, NPY, LHRH, prostaglandins, Substance P, CGRP, ANP, histamine, No, Ednothelin

11

NO

short-lived gas mediates relaxation of stomach induced by vagal PNS stimulation of other muscle from intrinsic NANC nerves