Poikilocytes Flashcards
(20 cards)
Deep staining large oval red cell associated with megaloblastic anemia and pernicious anemia
Macroovalocyte
Decreased surface area:volume ratio
Small, dense RBC with no central pallor
Loss of lipid membrane
Spherocyte / Bronze Cell
Disease associated with spherocyte/bronze cell
Hereditary Spherocytosis
AIHA
Severe Burns
Few irregularly spaced projections with varying lengths/widths
Acanthocytes / Thorn Cells / Spur Cells
Diseases associated with Acanthocytes / Thorn Cells / Spur Cells
Severe Liver Disease
McLeod Syndrome (Decreased expression of Kell)
Abetalipoproteinemia
RBC with blunt or pointed, short projections that are evenly spaced
Resembles crenated RBCs
Echinocytes / Burr Cells
Disease associated with Echinocytes / Burr Cells
Uremia due to kidney disease failure
Pyruvate kinase deficiency
Hb concentrated in the center and around the periphery with increased surface membrane ratio
Target Cell / Mexican Hat Cell / Codocyte / Leptocyte
Thin form of target cell
Leptocyte
Diseases associated with Target Cells
Liver disease
Hb C disease
Thalassemia
Slit-like / mouth-like area of central pallor
Stomatocyte
Disease associated with stomatocyte
Acute alcoholism
Rh null syndrome
Hereditary stomatocytosis
Narrow oval cells / egg-shaped / cigar-shaped cells
Elliptocytes
Disease associated with elliptocytes
Hereditary elliptocytosis
IDA
Thalassemia major
Fragmented RBCs caused by rupture in PERIPHERAL CIRCULATION usually involved in intravascular hemolysis
Schistocyte / Helmet / Keratocyte / RBC Fragment
Diseases associated with Schistocyte
MAHA, DIC, HUS, TTP
Severe Burns
Has single pointed extension resembling tear drop / pear
Dacryocte / Teardrop Cell
Disease associated with teardrop cell
Primary myelofibrosis
Thalassemia
Myelophthisic anemia
Megaloblastic anemia
Crescent-shaped cell
Caused by cryastallization of Hb S due to decreased O2 tension
Sickle Cell / Drepanocyte
Disease associated with Sickle Cell / Drepanocyte
Sickle Cell Anemia
Sickle Cell-beta thalassemia
